The malin–laforin complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin–proteasome system P Garyali, P Siwach, PK Singh, R Puri, S Mittal, S Sengupta, R Parihar, ... Human molecular genetics 18 (4), 688-700, 2009 | 128 | 2009 |
Cerebellar ataxia and coenzyme Q deficiency through loss of unorthodox kinase activity JA Stefely, F Licitra, L Laredj, AG Reidenbach, ZA Kemmerer, ... Molecular cell 63 (4), 608-620, 2016 | 121 | 2016 |
Decreased O-linked GlcNAcylation protects from cytotoxicity mediated by huntingtin exon1 protein fragment A Kumar, PK Singh, R Parihar, V Dwivedi, SC Lakhotia, S Ganesh Journal of Biological chemistry 289 (19), 13543-13553, 2014 | 75 | 2014 |
Activation of serum/glucocorticoid-induced kinase 1 (SGK1) underlies increased glycogen levels, mTOR activation, and autophagy defects in Lafora disease PK Singh, S Singh, S Ganesh Molecular biology of the cell 24 (24), 3776-3786, 2013 | 46 | 2013 |
The laforin-malin complex negatively regulates glycogen synthesis by modulating cellular glucose uptake via glucose transporters PK Singh, S Singh, S Ganesh Molecular and cellular biology 32 (3), 652-663, 2012 | 45 | 2012 |
Coumarin–pyrene conjugate: synthesis, structure and Cu-selective fluorescent sensing in mammalian kidney cells MA Wani, PK Singh, R Pandey, MD Pandey Journal of Luminescence 171, 159-165, 2016 | 37 | 2016 |
Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux A Rai, PK Singh, V Singh, V Kumar, R Mishra, AK Thakur, A Mahadevan, ... Cell death & disease 9 (2), 201, 2018 | 36 | 2018 |
Lafora disease E3 ubiquitin ligase malin is recruited to the processing bodies and regulates the microRNA-mediated gene silencing process via the decapping enzyme Dcp1a S Singh, PK Singh, P Bhadauriya, S Ganesh RNA biology 9 (12), 1440-1449, 2012 | 24 | 2012 |
Changing shapes of glycogen–autophagy nexus in neurons: perspective from a rare epilepsy PK Singh, S Singh Frontiers in Neurology 6, 14, 2015 | 15 | 2015 |
Lysine l-lactylation is the dominant lactylation isomer induced by glycolysis D Zhang, J Gao, Z Zhu, Q Mao, Z Xu, PK Singh, CC Rimayi, ... Nature Chemical Biology, 1-9, 2024 | 10 | 2024 |
Interdependence of laforin and malin proteins for their stability and functions could underlie the molecular basis of locus heterogeneity in Lafora disease S Mittal, M Upadhyay, P Kumar Singh, R Parihar, S Ganesh Journal of biosciences 40, 863-871, 2015 | 10 | 2015 |
Biochemical characterization of spleen tyrosine kinase (SYK) isoforms in platelets P Kumar Singh, CA Dangelmaier, H Reddy Vari, AY Tsygankov, ... Platelets 34 (1), 2249549, 2023 | 4 | 2023 |
Phosphorylation of spleen tyrosine kinase at Y346 negatively regulates ITAM-mediated signaling and function in platelets CA Dangelmaier, M Patchin, DN Vajipayajula, HR Vari, PK Singh, ... Journal of Biological Chemistry 299 (7), 2023 | 3 | 2023 |
Coenzyme A governs proinflammatory macrophage metabolism GA Timblin, KM Tharp, J Hoeve, DS Kantner, I Baydemir, EA Noel, ... BioRxiv, 2022.08. 30.505732, 2022 | 2 | 2022 |
Neurological glycogen storage diseases and emerging therapeutics M Colpaert, PK Singh, KJ Donohue, NT Pires, DD Fuller, M Corti, ... Neurotherapeutics, e00446, 2024 | 1 | 2024 |
Alanine Modulates Lactyl‐CoA Abundance in HepG2 Cells PK Singh, A Bostwick, H Pepper, NW Snyder The FASEB Journal 36, 2022 | 1 | 2022 |
Cortical inhibitory parvalbumin interneurons exhibit metabolic specializations coordinated by PGC-1α that are lost in rodents and humans after traumatic brain injury S Quiñones, JC Wang, E Kim, S Bottom-Tanzer, M Armbruster, ... bioRxiv, 2024.06. 19.599637, 2024 | | 2024 |
Abstract 2334 Glycogen, a potential therapeutic target for Ewing Sarcoma Y Liu, L Young, P Singh, H Clarke, T Hawkinson, M McCall, R Sun, ... Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Autophagy Defects and Lafora Disease PK Singh, S Ganesh Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and …, 2016 | | 2016 |
Lysine l-lactylation is the dominant lactylation isomer induced by glycolysis Z Xu, PK Singh, CC Rimayi, C Moreno-Yruela, S Xu, G Li, YC Sin, Y Chen, ... | | |