Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF3 RB Seth, L Sun, CK Ea, ZJ Chen Cell 122 (5), 669-682, 2005 | 3803 | 2005 |
Activation of IKK by TNFα requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO CK Ea, L Deng, ZP Xia, G Pineda, ZJ Chen Molecular cell 22 (2), 245-257, 2006 | 1232 | 2006 |
TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains A Kanayama, RB Seth, L Sun, CK Ea, M Hong, A Shaito, YH Chiu, L Deng, ... Molecular cell 15 (4), 535-548, 2004 | 1088 | 2004 |
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes L Sun, L Deng, CK Ea, ZP Xia, ZJ Chen Molecular cell 14 (3), 289-301, 2004 | 864 | 2004 |
miR-146a controls the resolution of T cell responses in mice L Yang, MP Boldin, Y Yu, CS Liu, CK Ea, P Ramakrishnan, KD Taganov, ... Journal of Experimental Medicine 209 (9), 1655-1670, 2012 | 334 | 2012 |
Regulation of NF-κB activity through lysine monomethylation of p65 CK Ea, D Baltimore Proceedings of the National Academy of Sciences 106 (45), 18972-18977, 2009 | 266 | 2009 |
Increase of the resistance of human cervical carcinoma cells to cisplatin by inhibition of the MEK to ERK signaling pathway partly via enhancement of anticancer drug-induced … PY Yeh, SE Chuang, KH Yeh, YC Song, CK Ea, AL Cheng Biochemical pharmacology 63 (8), 1423-1430, 2002 | 185 | 2002 |
Inducible RasGEF1B circular RNA is a positive regulator of ICAM-1 in the TLR4/LPS pathway WL Ng, GK Marinov, ES Liau, YL Lam, YY Lim, CK Ea RNA biology 13 (9), 861-871, 2016 | 158 | 2016 |
TIFA activates IκB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6 CK Ea, L Sun, JI Inoue, ZJ Chen Proceedings of the National Academy of Sciences 101 (43), 15318-15323, 2004 | 158 | 2004 |
Nickel (II) complex of polyhydroxybenzaldehyde N4-thiosemicarbazone exhibits anti-inflammatory activity by inhibiting NF-κB transactivation HB Shawish, WY Wong, YL Wong, SW Loh, CY Looi, P Hassandarvish, ... PloS one 9 (6), e100933, 2014 | 82 | 2014 |
Ubiquitination and TRAF signaling G Pineda, CK Ea, ZJ Chen TNF Receptor Associated Factors (TRAFs), 80-92, 2007 | 75 | 2007 |
EHMT1 protein binds to nuclear factor-κB p50 and represses gene expression CK Ea, SL Hao, KS Yeo, D Baltimore Journal of Biological Chemistry 287 (37), 31207-31217, 2012 | 59 | 2012 |
Liquid phase separation of NEMO induced by polyubiquitin chains activates NF-κB M Du, CK Ea, Y Fang, ZJ Chen Molecular cell 82 (13), 2415-2426. e5, 2022 | 52 | 2022 |
Ubiquitin-like conjugation by bacterial cGAS enhances anti-phage defence JM Jenson, T Li, F Du, CK Ea, ZJ Chen Nature 616 (7956), 326-331, 2023 | 45 | 2023 |
Transcriptomic analysis of the role of RasGEF1B circular RNA in the TLR4/LPS pathway WL Ng, GK Marinov, YM Chin, YY Lim, CK Ea Scientific reports 7 (1), 12227, 2017 | 34 | 2017 |
JMJD8 is a positive regulator of TNF-induced NF-κB signaling KS Yeo, MC Tan, WY Wong, SW Loh, YL Lam, CL Tan, YY Lim, CK Ea Scientific reports 6 (1), 34125, 2016 | 29 | 2016 |
Inhibition of euchromatic histone methyltransferase 1 and 2 sensitizes chronic myeloid leukemia cells to interferon treatment SW Loh, WL Ng, KS Yeo, YY Lim, CK Ea PLoS One 9 (7), e103915, 2014 | 19 | 2014 |
JMJD8 is a novel endoplasmic reticulum protein with a JmjC domain KS Yeo, MC Tan, YY Lim, CK Ea Scientific reports 7 (1), 15407, 2017 | 15 | 2017 |
Identification and characterization of a novel Epstein-Barr Virus-encoded circular RNA from LMP-2 Gene KE Tan, WL Ng, GK Marinov, KHO Yu, LP Tan, ES Liau, SY Goh, KS Yeo, ... Scientific reports 11 (1), 14392, 2021 | 13 | 2021 |
A cell-based screening system for anti-influenza A virus agents WY Wong, SW Loh, WL Ng, MC Tan, KS Yeo, CY Looi, MJ Maah, CK Ea Scientific reports 5 (1), 8672, 2015 | 6 | 2015 |