Attaching and effacing bacterial effector NleC suppresses epithelial inflammatory responses by inhibiting NF-κB and p38 mitogen-activated protein kinase activation HP Sham, SR Shames, MA Croxen, C Ma, JM Chan, MA Khan, ... Infection and immunity 79 (9), 3552-3562, 2011 | 109 | 2011 |
Multiple Legionella pneumophila effector virulence phenotypes revealed through high-throughput analysis of targeted mutant libraries SR Shames, L Liu, JC Havey, WB Schofield, AL Goodman, CR Roy Proceedings of the National Academy of Sciences 114 (48), E10446-E10454, 2017 | 95 | 2017 |
Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17 K Arasaki, Y Mikami, SR Shames, H Inoue, Y Wakana, M Tagaya Nature communications 8 (1), 15406, 2017 | 91 | 2017 |
The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling SR Shames, W Deng, JA Guttman, CL De Hoog, Y Li, PR Hardwidge, ... Cellular microbiology 12 (9), 1322-1339, 2010 | 89 | 2010 |
Pathogenicity and Virulence of Legionella: Intracellular replication and host response D Chauhan, SR Shames Virulence 12 (1), 1122-1144, 2021 | 86 | 2021 |
Co-evolution and exploitation of host cell signaling pathways by bacterial pathogens SR Shames, SD Auweter, BB Finlay The international journal of biochemistry & cell biology 41 (2), 380-389, 2009 | 77 | 2009 |
The pathogenic Escherichia coli type III secreted protease NleC degrades the host acetyltransferase p300 SR Shames, AP Bhavsar, MA Croxen, RJ Law, SHC Mak, W Deng, Y Li, ... Cellular microbiology 13 (10), 1542-1557, 2011 | 68 | 2011 |
Bacterial effector interplay: a new way to view effector function SR Shames, BB Finlay Trends in microbiology 20 (5), 214-219, 2012 | 57 | 2012 |
The type III system-secreted effector EspZ localizes to host mitochondria and interacts with the translocase of inner mitochondrial membrane 17b SR Shames, MA Croxen, W Deng, BB Finlay Infection and immunity 79 (12), 4784-4790, 2011 | 43 | 2011 |
The Legionella pneumophila metaeffector Lpg2505 (MesI) regulates SidI-mediated translation inhibition and novel glycosyl hydrolase activity AM Joseph, AE Pohl, TJ Ball, TG Abram, DK Johnson, BV Geisbrecht, ... Infection and immunity 88 (5), 10.1128/iai. 00853-19, 2020 | 34 | 2020 |
Molecular basis of TCR selectivity, cross-reactivity, and allelic discrimination by a bacterial superantigen: integrative functional and energetic mapping of the SpeC-Vβ2. 1 … AKM Rahman, CA Herfst, B Moza, SR Shames, LA Chau, C Bueno, ... The Journal of Immunology 177 (12), 8595-8603, 2006 | 25 | 2006 |
Breaking the Stereotype: Virulence Factor–Mediated Protection of Host Cells in Bacterial Pathogenesis SR Shames, BB Finlay PLoS pathogens 6 (9), e1001057, 2010 | 24 | 2010 |
15-Deoxy-Δ12,14-Prostaglandin J2 Inhibits Macrophage Colonization by Salmonella enterica Serovar Typhimurium MMC Buckner, LCM Antunes, N Gill, SL Russell, SR Shames, BB Finlay PLoS One 8 (7), e69759, 2013 | 19 | 2013 |
Affecting the Effectors: Regulation of Legionella pneumophila Effector Function by Metaeffectors AM Joseph, SR Shames Pathogens 10 (2), 108, 2021 | 18 | 2021 |
Acyl Histidines: New N‐Acyl Amides from Legionella pneumophila T Tørring, SR Shames, W Cho, CR Roy, JM Crawford ChemBioChem 18 (7), 638-646, 2017 | 15 | 2017 |
Mechanisms of Effector-Mediated Immunity Revealed by the Accidental Human Pathogen Legionella pneumophila T Ngwaga, D Chauhan, SR Shames Frontiers in Cellular and Infection Microbiology 10, 593823, 2021 | 14 | 2021 |
Potentiation of Cytokine-Mediated Restriction of Legionella Intracellular Replication by a Dot/Icm-Translocated Effector T Ngwaga, AJ Hydock, S Ganesan, SR Shames Journal of Bacteriology 201 (14), 10.1128/jb. 00755-18, 2019 | 14 | 2019 |
Quantitative Mass Spectrometry Identifies Novel Host Binding Partners for Pathogenic Escherichia coli Type III Secretion System Effectors RJ Law, HT Law, JM Scurll, R Scholz, AS Santos, SR Shames, W Deng, ... Journal of proteome research 15 (5), 1613-1622, 2016 | 14 | 2016 |
High-polyphenol extracts from Sorghum bicolor attenuate replication of Legionella pneumophila within RAW 264.7 macrophages AK Gilchrist, D Smolensky, T Ngwaga, D Chauhan, S Cox, R Perumal, ... FEMS Microbiology Letters 367 (7), fnaa053, 2020 | 11 | 2020 |
Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17. Nat Commun 8: 15406 K Arasaki, Y Mikami, SR Shames, H Inoue, Y Wakana, M Tagaya | 11 | 2017 |