Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics MI Barton, SA MacGowan, MA Kutuzov, O Dushek, GJ Barton, ... Elife 10, e70658, 2021 | 305 | 2021 |
A generic cell surface ligand system for studying cell–cell recognition EM Denham, MI Barton, SM Black, MJ Bridge, B de Wet, RL Paterson, ... PLoS Biology 17 (12), e3000549, 2019 | 13 | 2019 |
Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity … SA MacGowan, MI Barton, M Kutuzov, O Dushek, PA van der Merwe, ... PLoS Computational Biology 18 (3), e1009922, 2022 | 12 | 2022 |
Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors A Patel, V Andre, SB Eguiguren, MI Barton, J Burton, EM Denham, ... The EMBO Journal 43 (1), 132-150, 2024 | 4* | 2024 |
A structure-function analysis shows SARS-CoV-2 BA. 2.86 balances antibody escape and ACE2 affinity C Liu, D Zhou, A Dijokaite-Guraliuc, P Supasa, HME Duyvesteyn, ... Cell Reports Medicine 5 (5), 2024 | 1 | 2024 |
Ligand requirements for immunoreceptor triggering MI Barton, RL Paterson, EM Denham, J Goyette, PA van der Merwe bioRxiv, 2023.09. 11.557203, 2023 | | 2023 |
Analysis of emergent bivalent antibody binding identifies the molecular reach as a critical determinant of SARS-CoV-2 neutralisation potency A Huhn, D Nissley, DB Wilson, M Kutuzov, R Donat, TK Tan, Y Zhang, ... bioRxiv, 2023.09. 06.556503, 2023 | | 2023 |
Studies on immunoreceptor activation and SARS-CoV-2 RBD/ACE2 interactions MI Barton University of Oxford, 2022 | | 2022 |