| Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly T Thakar, W Leung, CM Nicolae, KE Clements, B Shen, AK Bielinsky, ... Nature communications 11 (1), 2147, 2020 | 125 | 2020 |
| Activation of Wnt signaling promotes olaparib resistant ovarian cancer TM Yamamoto, A McMellen, ZL Watson, J Aguilera, R Ferguson, ... Molecular carcinogenesis 58 (10), 1770-1782, 2019 | 93 | 2019 |
| Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells KE Clements, T Thakar, CM Nicolae, X Liang, HG Wang, GL Moldovan Nucleic acids research 46 (17), 8898-8907, 2018 | 64 | 2018 |
| The emerging determinants of replication fork stability T Thakar, GL Moldovan Nucleic acids research 49 (13), 7224-7238, 2021 | 57 | 2021 |
| Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens KE Clements, EM Schleicher, T Thakar, A Hale, A Dhoonmoon, ... Nature communications 11 (1), 6118, 2020 | 48 | 2020 |
| PARP14 regulates cyclin D1 expression to promote cell-cycle progression MJ O’Connor, T Thakar, CM Nicolae, GL Moldovan Oncogene 40 (30), 4872-4883, 2021 | 41 | 2021 |
| WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells A Datta, K Biswas, JA Sommers, H Thompson, S Awate, CM Nicolae, ... Nature communications 12 (1), 6561, 2021 | 32 | 2021 |
| SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion G Leuzzi, A Vasciaveo, A Taglialatela, X Chen, TM Firestone, ... Cell 187 (4), 861-881. e32, 2024 | 24 | 2024 |
| Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly through PCNA-dependent CAF-1 recycling T Thakar, A Dhoonmoon, J Straka, EM Schleicher, CM Nicolae, ... Nature communications 13 (1), 5323, 2022 | 23 | 2022 |
| FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination W Leung, RM Baxley, E Traband, YC Chang, CB Rogers, L Wang, ... Cell reports 42 (12), 2023 | 9 | 2023 |
| Targeting Wnt signaling to overcome PARP inhibitor resistance TM Yamamoto, A McMellen, ZL Watson, J Aguilera, MJ Sikora, ... BioRxiv, 378463, 2018 | 8 | 2018 |
| Identification of regulators of poly-ADP-ribose polymerase (PARP) inhibitor response through complementary CRISPR knockout and activation screens KE Clements, A Hale, NJ Tolman, CM Nicolae, A Sharma, T Thakar, ... bioRxiv, 871970, 2019 | 7 | 2019 |
| PCNA-K164 ubiquitination facilitates origin licensing and mitotic DNA synthesis W Leung, R Baxley, T Thakar, C Rogers, J Buytendorp, L Wang, A Tella, ... BioRxiv, 2020 | 4 | 2020 |
| PCNA ubiquitination protects stalled replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly T Thakar, W Leung, CM Nicolae, KE Clements, B Shen, AK Bielinsky, ... BioRxiv, 759985, 2019 | 3 | 2019 |
| Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly by ensuring PCNA-dependent CAF-1 recycling T Thakar, J Straka, CM Nicolae, GL Moldovan bioRxiv, 2021.11. 08.467732, 2021 | 2 | 2021 |
| A PCNA-K164R mutation impinges on origin activation and mitotic DNA synthesis W Leung, RM Baxley, T Thakar, YC Chang, CB Rogers, L Wang, ... bioRxiv, 2020.06. 25.172361, 2020 | 2 | 2020 |
| Base-editing screens illuminate variant effects in human hematopoiesis A Vaitsiankova, T Thakar, A Ciccia Cell Reports Methods 3 (7), 2023 | | 2023 |
| Assessing the Role of Gap-Avoidance Mechanisms and Nucleosome Assembly Pathways as Guardians of DNA Replication Fork Stability T Thakar | | 2022 |
| Abstract GMM-040: TARGETING WNT SIGNALING TO OVERCOME PARP INHIBITOR RESISTANCE TM Yamamoto, A McMellen, ZL Watson, J Aguilera, MJ Sikora, ... Clinical Cancer Research 25 (22_Supplement), GMM-040-GMM-040, 2019 | | 2019 |
