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Jeffrey A Willy
Jeffrey A Willy
在 vrtx.com 的电子邮件经过验证
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Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver
ME Fusakio, JA Willy, Y Wang, ET Mirek, RJT Al Baghdadi, CM Adams, ...
Molecular biology of the cell 27 (9), 1536-1551, 2016
2282016
CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis
JA Willy, SK Young, JL Stevens, HC Masuoka, RC Wek
Molecular biology of the cell 26 (12), 2190-2204, 2015
1362015
Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα
TD Baird, LR Palam, ME Fusakio, JA Willy, CM Davis, JN McClintick, ...
Molecular biology of the cell 25 (10), 1686-1697, 2014
1322014
Ribosome reinitiation directs gene-specific translation and regulates the integrated stress response
SK Young, JA Willy, C Wu, MS Sachs, RC Wek
Journal of Biological Chemistry 290 (47), 28257-28271, 2015
962015
Toxicogenomic module associations with pathogenesis: a network-based approach to understanding drug toxicity
JJ Sutherland, YW Webster, JA Willy, GH Searfoss, KM Goldstein, ...
The pharmacogenomics journal 18 (3), 377-390, 2018
862018
Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential
JJ Kwon, JA Willy, KA Quirin, RC Wek, M Korc, XM Yin, J Kota
Oncotarget 7 (44), 71635, 2016
702016
Function of inhibitor of Bruton's tyrosine kinase isoform α (IBTKα) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response
JA Willy, SK Young, AL Mosley, S Gawrieh, JL Stevens, HC Masuoka, ...
Journal of Biological Chemistry 292 (34), 14050-14065, 2017
222017
FcγRIIIa-dependent IFN-γ release in whole blood assay is predictive of therapeutic IgG1 antibodies safety
NS Alakhras, J Qiu, GV Rocha, DR Witcher, A Koester, J You, DA Schaer, ...
MAbs 10 (6), 913-921, 2018
72018
The integrated stress response regulates cell health of cardiac progenitors
GH Searfoss, BM Paisley, KM Goldstein, TK Baker, JA Willy
Toxicological Sciences 167 (1), 202-210, 2019
52019
In Vitro L6 Irritation Assay Predicts Clinical Injection Site Reactions for Small Molecules
JA Willy, NE Schulte, EL Kreklau, JL Walgren, ML Renninger, TK Baker
Toxicological Sciences 151 (2), 302-311, 2016
52016
Discover Toxicology: An Early Safety Assessment Approach
TK Baker, SK Engle, BW Halstead, BM Paisley, GH Searfoss, JA Willy
Translating Molecules into Medicines: Cross-Functional Integration at the …, 2017
12017
ER Stress Regulates Autophagy and Protein Secretion through IBTK alpha during the Pathogenesis of Non-Alcoholic Steatohepatitis
JA Willy, S Gawrieh, JL Stevens, HC Masuoka, RC Wek
HEPATOLOGY 63 (1 SUPP), 796A-797A, 2016
2016
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