Identification of the maturation factor for dual oxidase: evolution of an eukaryotic operon equivalent H Grasberger, S Refetoff Journal of Biological Chemistry 281 (27), 18269-18272, 2006 | 382 | 2006 |
Genetic causes of congenital hypothyroidism due to dyshormonogenesis H Grasberger, S Refetoff Current opinion in pediatrics 23 (4), 421-428, 2011 | 258 | 2011 |
Activation of dual oxidases Duox1 and Duox2 S Rigutto, C Hoste, H Grasberger, M Milenkovic, D Communi, JE Dumont, ... Journal of Biological Chemistry 284 (11), 6725-6734, 2009 | 249 | 2009 |
Functional characterization of inflammatory bowel disease–associated gut dysbiosis in gnotobiotic mice H Nagao-Kitamoto, AB Shreiner, MG Gillilland III, S Kitamoto, C Ishii, ... Cellular and molecular gastroenterology and hepatology 2 (4), 468-481, 2016 | 223 | 2016 |
DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses S Lipinski, A Till, C Sina, A Arlt, H Grasberger, S Schreiber, P Rosenstiel Journal of cell science 122 (19), 3522-3530, 2009 | 220 | 2009 |
Biallelic Inactivation of the Dual Oxidase Maturation Factor 2 (DUOXA2) Gene as a Novel Cause of Congenital Hypothyroidism I Zamproni, H Grasberger, F Cortinovis, MC Vigone, G Chiumello, S Mora, ... The Journal of Clinical Endocrinology & Metabolism 93 (2), 605-610, 2008 | 203 | 2008 |
Increased expression of DUOX2 is an epithelial response to mucosal dysbiosis required for immune homeostasis in mouse intestine H Grasberger, J Gao, H Nagao-Kitamoto, S Kitamoto, M Zhang, ... Gastroenterology 149 (7), 1849-1859, 2015 | 131 | 2015 |
Defects of thyroidal hydrogen peroxide generation in congenital hypothyroidism H Grasberger Molecular and cellular endocrinology 322 (1-2), 99-106, 2010 | 127 | 2010 |
A Familial Thyrotropin (TSH) Receptor Mutation Provides in Vivo Evidence that the Inositol Phosphates/Ca2+ Cascade Mediates TSH Action on Thyroid Hormone … H Grasberger, J Van Sande, A Hag-Dahood Mahameed, ... The journal of clinical endocrinology & metabolism 92 (7), 2816-2820, 2007 | 122 | 2007 |
Dietary l-serine confers a competitive fitness advantage to Enterobacteriaceae in the inflamed gut S Kitamoto, CJ Alteri, M Rodrigues, H Nagao-Kitamoto, K Sugihara, ... Nature Microbiology 5 (1), 116-125, 2020 | 117 | 2020 |
Dual oxidases control release of hydrogen peroxide by the gastric epithelium to prevent Helicobacter felis infection and inflammation in mice H Grasberger, M El–Zaatari, DT Dang, JL Merchant Gastroenterology 145 (5), 1045-1054, 2013 | 107 | 2013 |
Missense Mutations of Dual Oxidase 2 (DUOX2) Implicated in Congenital Hypothyroidism Have Impaired Trafficking in Cells Reconstituted with DUOX2 Maturation … H Grasberger, X De Deken, F Miot, J Pohlenz, S Refetoff Molecular Endocrinology 21 (6), 1408-1421, 2007 | 98 | 2007 |
Mice deficient in dual oxidase maturation factors are severely hypothyroid H Grasberger, X De Deken, OB Mayo, H Raad, M Weiss, XH Liao, ... Molecular endocrinology 26 (3), 481-492, 2012 | 96 | 2012 |
Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity H Grasberger, U Ringkananont, P LeFrancois, M Abramowicz, G Vassart, ... Molecular endocrinology 19 (7), 1779-1791, 2005 | 96 | 2005 |
The tumour necrosis factor-alpha induced vascular permeability is associated with a reduction of VE-cadherin expression. S Hofmann, H Grasberger, P Jung, M Bidlingmaier, J Vlotides, ... European journal of medical research 7 (4), 171-176, 2002 | 92 | 2002 |
A single copy of the recently identified dual oxidase maturation factor (DUOXA) 1 gene produces only mild transient hypothyroidism in a patient with a novel biallelic DUOXA2 … I Hulur, P Hermanns, C Nestoris, S Heger, S Refetoff, J Pohlenz, ... The Journal of Clinical Endocrinology & Metabolism 96 (5), E841-E845, 2011 | 75 | 2011 |
Dual oxidase regulates neutrophil recruitment in allergic airways S Chang, A Linderholm, L Franzi, N Kenyon, H Grasberger, R Harper Free Radical Biology and Medicine 65, 38-46, 2013 | 70 | 2013 |
Tryptophan catabolism restricts IFN-γ–expressing neutrophils and Clostridium difficile immunopathology M El-Zaatari, YM Chang, M Zhang, M Franz, A Shreiner, AJ McDermott, ... The Journal of Immunology 193 (2), 807-816, 2014 | 64 | 2014 |
Genetic complexity of Crohn’s disease in two large Ashkenazi Jewish families AP Levine, N Pontikos, ER Schiff, L Jostins, D Speed, LB Lovat, JC Barrett, ... Gastroenterology 151 (4), 698-709, 2016 | 61 | 2016 |
CD4+ Tissue-resident Memory T Cells Expand and Are a Major Source of Mucosal Tumour Necrosis Factor α in Active Crohn’s Disease S Bishu, M El Zaatari, A Hayashi, G Hou, N Bowers, J Kinnucan, ... Journal of Crohn's and Colitis 13 (7), 905-915, 2019 | 58 | 2019 |