A three-base-pair deletion in the peripherin–RDS gene in one form of retinitis pigmentosa GJ Farrar, P Kenna, SA Jordan, R Kumar-Singh, MM Humphries, ... Nature 354 (6353), 478-480, 1991 | 492 | 1991 |
Encapsidated adenovirus minichromosomes allow delivery and expression of a 14 kb dystrophin cDNA to muscle cells R Kumar-Singh, JS Chamberlain Human Molecular Genetics 5 (7), 913-921, 1996 | 228 | 1996 |
Cell-penetrating peptide for enhanced delivery of nucleic acids and drugs to ocular tissues including retina and cornea LN Johnson, SM Cashman, R Kumar-Singh Molecular Therapy 16 (1), 107-114, 2008 | 181 | 2008 |
Encapsidated adenovirus mini-chromosome-mediated delivery of genes to the retina: application to the rescue of photoreceptor degeneration R Kumar-Singh, DB Farber Human molecular genetics 7 (12), 1893-1900, 1998 | 148 | 1998 |
A non membrane-targeted human soluble CD59 attenuates choroidal neovascularization in a model of age related macular degeneration SM Cashman, K Ramo, R Kumar-Singh PloS one 6 (4), e19078, 2011 | 133 | 2011 |
Mutation in CEP290 Discovered for Cat Model of Human Retinal Degeneration M Menotti-Raymond, VA David, AA Schäffer, R Stephens, D Wells, ... Journal of Heredity 98 (3), 211-220, 2007 | 127 | 2007 |
Localization of an autosomal dominant retinitis pigmentosa gene to chromosome 7q SA Jordan, GJ Farrar, P Kenna, MM Humphries, DM Sheils, ... Nature genetics 4 (1), 54-58, 1993 | 122 | 1993 |
Adenovirus vectors JS Chamberlain, R Kumar-Singh US Patent 5,994,132, 1999 | 114 | 1999 |
Cell penetrating peptide POD mediates delivery of recombinant proteins to retina, cornea and skin LN Johnson, SM Cashman, SP Read, R Kumar-Singh Vision research 50 (7), 686-697, 2010 | 92 | 2010 |
Autosomal dominant retinitis pigmentosa: localization of a disease gene (RP6) to the short arm of chromosome 6 GJ Farrar, SA Jordan, P Kenna, MM Humphries, R Kumar-Singh, ... Genomics 11 (4), 870-874, 1991 | 89 | 1991 |
Inhibition of choroidal neovascularization by adenovirus-mediated delivery of short hairpin RNAs targeting VEGF as a potential therapy for AMD SM Cashman, L Bowman, J Christofferson, R Kumar-Singh Investigative ophthalmology & visual science 47 (8), 3496-3504, 2006 | 82 | 2006 |
Intercellular trafficking of adenovirus-delivered HSV VP22 from the retinal pigment epithelium to the photoreceptors—implications for gene therapy SM Cashman, SL Sadowski, DJ Morris, J Frederick, R Kumar-Singh Molecular Therapy 6 (6), 813-823, 2002 | 80 | 2002 |
Autosomal dominant retinitis pigmentosa: a novel mutation at the peripherin/RDS locus in the original 6p-linked pedigree GJ Farrar, P Kenna, SA Jordan, R Kumar-Singh, MM Humphries, ... Genomics 14 (3), 805-807, 1992 | 76 | 1992 |
A mutation (Met→ Arg) in the type I keratin (K14) gene responsible for autosomal dominant epidermolysis bullosa simplex MM Humphries, DM Sheils, GJ Farrar, R Kumar‐Singh, PF Kenna, ... Human Mutation 2 (1), 37-42, 1993 | 72 | 1993 |
Towards mutation-independent silencing of genes involved in retinal degeneration by RNA interference SM Cashman, EA Binkley, R Kumar-Singh Gene Therapy 12 (15), 1223-1228, 2005 | 66 | 2005 |
Evidence of protein transduction but not intercellular transport by proteins fused to HIV tat in retinal cell culture and in vivo SM Cashman, DJ Morris, R Kumar-Singh Molecular Therapy 8 (1), 130-142, 2003 | 65 | 2003 |
Expression of complement component 3 (C3) from an adenovirus leads to pathology in the murine retina SM Cashman, A Desai, K Ramo, R Kumar-Singh Investigative ophthalmology & visual science 52 (6), 3436-3445, 2011 | 64 | 2011 |
POD nanoparticles expressing GDNF provide structural and functional rescue of light-induced retinal degeneration in an adult mouse SP Read, SM Cashman, R Kumar-Singh Molecular Therapy 18 (11), 1917-1926, 2010 | 64 | 2010 |
Adenovirus vectors JS Chamberlain, R Kumar-Singh US Patent 6,083,750, 2000 | 61 | 2000 |
The role of complement membrane attack complex in dry and wet AMD-From hypothesis to clinical trials R Kumar-Singh Experimental eye research 184, 266-277, 2019 | 57 | 2019 |