Bortezomib combination therapy in multiple myeloma P Kapoor, V Ramakrishnan, SV Rajkumar Seminars in hematology 49 (3), 228-242, 2012 | 115 | 2012 |
Sorafenib, a dual Raf kinase/vascular endothelial growth factor receptor inhibitor has significant anti-myeloma activity and synergizes with common anti-myeloma drugs V Ramakrishnan, M Timm, JL Haug, TK Kimlinger, LE Wellik, TE Witzig, ... Oncogene 29 (8), 1190-1202, 2010 | 114 | 2010 |
PI3K/AKT/mTOR pathway in multiple myeloma: from basic biology to clinical promise V Ramakrishnan, S Kumar Leukemia & lymphoma 59 (11), 2524-2534, 2018 | 85 | 2018 |
TG101209, a novel JAK2 inhibitor, has significant in vitro activity in multiple myeloma and displays preferential cytotoxicity for CD45+ myeloma cells V Ramakrishnan, T Kimlinger, J Haug, M Timm, L Wellik, T Halling, ... American journal of hematology 85 (9), 675-686, 2010 | 82 | 2010 |
MRK003, a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma V Ramakrishnan, S Ansell, J Haug, D Grote, T Kimlinger, M Stenson, ... Leukemia 26 (2), 340-348, 2012 | 79 | 2012 |
Anti-myeloma activity of Akt inhibition is linked to the activation status of PI3K/Akt and MEK/ERK pathway V Ramakrishnan, T Kimlinger, J Haug, U Painuly, L Wellik, T Halling, ... PloS one 7 (11), e50005, 2012 | 75 | 2012 |
Clinical use and applications of histone deacetylase inhibitors in multiple myeloma N Tandon, V Ramakrishnan, SK Kumar Clinical pharmacology: advances and applications, 35-44, 2016 | 71 | 2016 |
Inhibitor of apoptosis proteins as therapeutic targets in multiple myeloma V Ramakrishnan, U Painuly, T Kimlinger, J Haug, SV Rajkumar, S Kumar Leukemia 28 (7), 1519-1528, 2014 | 60 | 2014 |
Amblyomma americanum salivary glands: double-stranded RNA-mediated gene silencing of synaptobrevin homologue and inhibition of PGE2 stimulated protein secretion S Karim, VG Ramakrishnan, JS Tucker, RC Essenberg, JR Sauer Insect biochemistry and molecular biology 34 (4), 407-413, 2004 | 59 | 2004 |
Glutamine-derived 2-hydroxyglutarate is associated with disease progression in plasma cell malignancies WI Gonsalves, V Ramakrishnan, T Hitosugi, T Ghosh, D Jevremovic, ... JCI insight 3 (1), 2018 | 55 | 2018 |
Sorafenib, a multikinase inhibitor, is effective in vitro against non‐hodgkin lymphoma and synergizes with the mTOR inhibitor rapamycin V Ramakrishnan, M Timm, JL Haug, TK Kimlinger, T Halling, LE Wellik, ... American journal of hematology 87 (3), 277-283, 2012 | 39 | 2012 |
Microarray analysis of gene expression changes in feeding female and male lone star ticks, Amblyomma americanum (L) MN Aljamali, VG Ramakrishnan, H Weng, JS Tucker, JR Sauer, ... Archives of Insect Biochemistry and Physiology: Published in Collaboration …, 2009 | 39 | 2009 |
Signaling pathways and emerging therapies in multiple myeloma V Ramakrishnan, A D’Souza Current hematologic malignancy reports 11, 156-164, 2016 | 35 | 2016 |
Histone deacetylase inhibition in combination with MEK or BCL-2 inhibition in multiple myeloma VG Ramakrishnan, KC Miller, EP Macon, TK Kimlinger, J Haug, S Kumar, ... Haematologica 104 (10), 2061, 2019 | 33 | 2019 |
Amblyomma americanum salivary gland homolog of nSec1 is essential for saliva protein secretion S Karim, VG Ramakrishnan, JS Tucker, RC Essenberg, JR Sauer Biochemical and biophysical research communications 324 (4), 1256-1263, 2004 | 33 | 2004 |
Smac mimetic LCL161 overcomes protective ER stress induced by obatoclax, synergistically causing cell death in multiple myeloma V Ramakrishnan, M Gomez, V Prasad, T Kimlinger, U Painuly, ... Oncotarget 7 (35), 56253, 2016 | 30 | 2016 |
Application of RNA interference in tick salivary gland research VG Ramakrishnan, MN Aljamali, JR Sauer, RC Essenberg Journal of Biomolecular Techniques: JBT 16 (4), 297, 2005 | 30 | 2005 |
Multiple mechanisms contribute to the synergistic anti-myeloma activity of the pan-histone deacetylase inhibitor LBH589 and the rapalog RAD001 V Ramakrishnan, T Kimlinger, M Timm, J Haug, SV Rajkumar, S Kumar Leukemia research 38 (11), 1358-1366, 2014 | 16 | 2014 |
In vitro and ex vivo gene expression profiling reveals differential kinetic response of HSPs and UPR genes is associated with PI resistance in multiple myeloma AK Mitra, H Kumar, V Ramakrishnan, L Chen, L Baughn, S Kumar, ... Blood cancer journal 10 (7), 78, 2020 | 14 | 2020 |
Natriuretic peptides, inflammation, and sounding the alarm V Ramakrishnan, JC Burnett Jr Circulation: Heart Failure 13 (7), e007208, 2020 | 11 | 2020 |