Organocatalytic Asymmetric Synthesis of Six‐Membered Carbocycle‐Based Spiro Compounds X Xie, W Huang, C Peng, B Han Advanced Synthesis & Catalysis 360 (2), 194-228, 2018 | 118 | 2018 |
Asymmetric synthesis of a structurally and stereochemically complex spirooxindole pyran scaffold through an organocatalytic multicomponent cascade reaction X Xie, C Peng, G He, HJ Leng, B Wang, W Huang, B Han Chemical Communications 48 (85), 10487-10489, 2012 | 82 | 2012 |
Oridonin: a review of its pharmacology, pharmacokinetics and toxicity X Li, CT Zhang, W Ma, X Xie, Q Huang Frontiers in pharmacology 12, 645824, 2021 | 74 | 2021 |
Catalytic asymmetric synthesis of spiropyrazolones and their application in medicinal chemistry X Xie, L Xiang, C Peng, B Han The Chemical Record 19 (11), 2209-2235, 2019 | 73 | 2019 |
Naturally derived indole alkaloids targeting regulated cell death (RCD) for cancer therapy: from molecular mechanisms to potential therapeutic targets R Qin, FM You, Q Zhao, X Xie, C Peng, G Zhan, B Han Journal of hematology & oncology 15 (1), 133, 2022 | 47 | 2022 |
Recent advances in targeting the “undruggable” proteins: from drug discovery to clinical trials X Xie, T Yu, X Li, N Zhang, LJ Foster, C Peng, W Huang, G He Signal transduction and targeted therapy 8 (1), 335, 2023 | 42 | 2023 |
Role of licochalcone A in potential pharmacological therapy: a review MT Li, L Xie, HM Jiang, Q Huang, RS Tong, X Li, X Xie, HM Liu Frontiers in Pharmacology 13, 878776, 2022 | 37 | 2022 |
Organocatalytic tandem Morita–Baylis–Hillman–Michael reaction for asymmetric synthesis of a drug-like oxa-spirocyclic indanone scaffold X Li, L Yang, C Peng, X Xie, HJ Leng, B Wang, ZW Tang, G He, L Ouyang, ... Chemical communications 49 (77), 8692-8694, 2013 | 37 | 2013 |
Organocatalytic Morita–Baylis–Hillman/Michael/Acetalization Cascade: Procedure‐Controlled Diastereodivergence in the Asymmetric Synthesis of Fully Substituted Tetrahydropyrans B Han, X Xie, W Huang, X Li, L Yang, C Peng Advanced Synthesis & Catalysis 356 (17), 3676-3682, 2014 | 33 | 2014 |
Novel HSP90-PI3K dual inhibitor suppresses melanoma cell proliferation by interfering with HSP90-EGFR interaction and downstream signaling pathways Q Zhao, HP Zhu, X Xie, Q Mao, YQ Liu, XH He, C Peng, QL Jiang, ... International Journal of Molecular Sciences 21 (5), 1845, 2020 | 32 | 2020 |
Evodiamine alleviates lipopolysaccharide‐induced pulmonary inflammation and fibrosis by activating apelin pathway C Ye, N Zhang, Q Zhao, X Xie, X Li, HP Zhu, C Peng, W Huang, B Han Phytotherapy Research 35 (6), 3406-3417, 2021 | 21 | 2021 |
Discovery of spirooxindole–ferrocene hybrids as novel MDM2 inhibitors J Mu, X Xie, S Xiong, Y Zhang, Y Wang, Q Zhao, H Zhu, W Huang, G He Chinese Chemical Letters 32 (6), 1897-1901, 2021 | 19 | 2021 |
Computational analysis of spiro-oxindole inhibitors of the MDM2-p53 interaction: insights and selection of novel inhibitors W Huang, L Cai, C Chen, X Xie, Q Zhao, X Zhao, H Zhou, B Han, C Peng Journal of Biomolecular Structure and Dynamics 34 (2), 341-351, 2016 | 19 | 2016 |
Application of novel degraders employing autophagy for expediting medicinal research X Li, Q Liu, X Xie, C Peng, Q Pang, B Liu, B Han Journal of Medicinal Chemistry 66 (3), 1700-1711, 2023 | 17 | 2023 |
Design and organocatalytic synthesis of spirooxindole–cyclopentene–isoxazole hybrids as novel MDM2–p53 inhibitors X Xie, SS Xiong, X Li, H Huang, FB Wu, PF Shen, C Peng, G He, B Han Organic Chemistry Frontiers 8 (8), 1836-1843, 2021 | 13 | 2021 |
Asymmetric synthesis of oxa-spirocyclic indanones with structural complexity via an organocatalytic Michael–Henry–acetalization cascade X Xie, C Peng, HJ Leng, B Wang, ZW Tang, W Huang Synlett 25 (01), 143-147, 2014 | 10 | 2014 |
Targeting bromodomain-containing proteins: Research advances of drug discovery Z Pan, Y Zhao, X Wang, X Xie, M Liu, K Zhang, L Wang, D Bai, LJ Foster, ... Molecular Biomedicine 4 (1), 13, 2023 | 8 | 2023 |
Role of potential bioactive metabolites from traditional Chinese medicine for type 2 diabetes mellitus: An overview X Li, JJ Geng-Ji, YY Quan, LM Qi, Q Sun, Q Huang, HM Jiang, ZJ Sun, ... Frontiers in Pharmacology 13, 1023713, 2022 | 8 | 2022 |
Small-molecule dual inhibitors targeting heat shock protein 90 for cancer targeted therapy X Xie, N Zhang, X Li, H Huang, C Peng, W Huang, LJ Foster, G He, B Han Bioorganic Chemistry, 106721, 2023 | 7 | 2023 |
Unraveling the structures, functions and mechanisms of epithelial membrane protein family in human cancers N Zhang, HP Zhu, W Huang, X Wen, X Xie, X Jiang, C Peng, B Han, G He Experimental hematology & oncology 11 (1), 69, 2022 | 7 | 2022 |