Guts and gall: bile acids in regulation of intestinal epithelial function in health and disease P Hegyi, J Maléth, JR Walters, AF Hofmann, SJ Keely Physiological reviews 98 (4), 1983-2023, 2018 | 241 | 2018 |
Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis J Maléth, A Balázs, P Pallagi, Z Balla, B Kui, M Katona, L Judák, I Németh, ... Gastroenterology 148 (2), 427-439. e16, 2015 | 215 | 2015 |
Translocation between PI(4,5)P2-poor and PI(4,5)P2-rich microdomains during store depletion determines STIM1 conformation and Orai1 gating J Maléth, S Choi, S Muallem, M Ahuja Nature communications 5 (1), 5843, 2014 | 145 | 2014 |
The STIM1 CTID domain determines access of SARAF to SOAR to regulate Orai1 channel function A Jha, M Ahuja, J Maléth, CM Moreno, JP Yuan, MS Kim, S Muallem Journal of Cell Biology 202 (1), 71-79, 2013 | 133 | 2013 |
CFTR: a new horizon in the pathomechanism and treatment of pancreatitis P Hegyi, M Wilschanski, S Muallem, GL Lukacs, M Sahin-Tóth, A Uc, ... Reviews of Physiology, Biochemistry and Pharmacology Vol. 170, 37-66, 2016 | 112 | 2016 |
Ca2+ toxicity and mitochondrial damage in acute pancreatitis: translational overview J Maléth, P Hegyi Philosophical Transactions of the Royal Society B: Biological Sciences 371 …, 2016 | 103 | 2016 |
Non-conjugated chenodeoxycholate induces severe mitochondrial damage and inhibits bicarbonate transport in pancreatic duct cells J Maléth, V Venglovecz, ZS Rázga, L Tiszlavicz, Z Rakonczay, P Hegyi Gut 60 (1), 136-138, 2011 | 100 | 2011 |
Trypsin reduces pancreatic ductal bicarbonate secretion by inhibiting CFTR Cl− channels and luminal anion exchangers P Pallagi, V Venglovecz, Z Rakonczay Jr, K Borka, A Korompay, B Ózsvári, ... Gastroenterology 141 (6), 2228-2239. e6, 2011 | 98 | 2011 |
cAMP and Ca2+ signaling in secretory epithelia: crosstalk and synergism M Ahuja, A Jha, J Maléth, S Park, S Muallem Cell calcium 55 (6), 385-393, 2014 | 87 | 2014 |
Central role of mitochondrial injury in the pathogenesis of acute pancreatitis J Maléth, Z Rakonczay Jr, V Venglovecz, NJ Dolman, P Hegyi Acta physiologica 207 (2), 226-235, 2013 | 81 | 2013 |
Calcium signaling in pancreatic ductal epithelial cells: an old friend and a nasty enemy J Maléth, P Hegyi Cell calcium 55 (6), 337-345, 2014 | 74 | 2014 |
Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells M Breunig, J Merkle, M Wagner, MK Melzer, TFE Barth, T Engleitner, ... Cell Stem Cell 28 (6), 1105-1124. e19, 2021 | 72 | 2021 |
Anoctamin 8 tethers endoplasmic reticulum and plasma membrane for assembly of Ca2+ signaling complexes at the ER/PM compartment A Jha, WY Chung, L Vachel, J Maleth, S Lake, G Zhang, M Ahuja, ... The EMBO journal 38 (12), e101452, 2019 | 70 | 2019 |
Cystic fibrosis of the pancreas: the role of CFTR channel in the regulation of intracellular Ca2+ signaling and mitochondrial function in the exocrine pancreas T Madácsy, P Pallagi, J Maleth Frontiers in Physiology 9, 417130, 2018 | 68 | 2018 |
Intracellular Ca2+ Signalling in the Pathogenesis of Acute Pancreatitis: Recent Advances and Translational Perspectives P Pallagi, T Madácsy, Á Varga, J Maléth International journal of molecular sciences 21 (11), 4005, 2020 | 65 | 2020 |
Ethanol and its non-oxidative metabolites profoundly inhibit CFTR function in pancreatic epithelial cells which is prevented by ATP supplementation L Judák, P Hegyi, Z Rakonczay, J Maléth, MA Gray, V Venglovecz Pflügers Archiv-European Journal of Physiology 466, 549-562, 2014 | 64 | 2014 |
Pancreatic ductal bicarbonate secretion: challenge of the acinar acid load P Hegyi, J Maléth, V Venglovecz, Z Rakonczay Jr Frontiers in physiology 2, 36, 2011 | 63 | 2011 |
The formin DAAM is required for coordination of the actin and microtubule cytoskeleton in axonal growth cones S Szikora, I Földi, K Tóth, E Migh, A Vig, B Bugyi, J Maléth, P Hegyi, ... Journal of cell science 130 (15), 2506-2519, 2017 | 61 | 2017 |
The role of pancreatic ductal secretion in protection against acute pancreatitis in mice P Pallagi, Z Balla, AK Singh, S Dósa, B Iványi, Z Kukor, A Tóth, B Riederer, ... Critical care medicine 42 (3), e177-e188, 2014 | 56 | 2014 |
The ER/PM microdomain, PI (4, 5) P2 and the regulation of STIM1–Orai1 channel function X Cao, S Choi, JJ Maléth, S Park, M Ahuja, S Muallem Cell calcium 58 (4), 342-348, 2015 | 54 | 2015 |