关注
Kevin J Barnham
Kevin J Barnham
未知所在单位机构
在 unimelb.edu.au 的电子邮件经过验证
标题
引用次数
引用次数
年份
Neurodegenerative diseases and oxidative stress
KJ Barnham, CL Masters, AI Bush
Nature reviews Drug discovery 3 (3), 205-214, 2004
39402004
Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice
RA Cherny, CS Atwood, ME Xilinas, DN Gray, WD Jones, CA McLean, ...
Neuron 30 (3), 665-676, 2001
18412001
Alzheimer's disease amyloid-β binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits
CC Curtain, F Ali, I Volitakis, RA Cherny, RS Norton, K Beyreuther, ...
Journal of Biological Chemistry 276 (23), 20466-20473, 2001
8352001
Metals in Alzheimer's and Parkinson's diseases
KJ Barnham, AI Bush
Current opinion in chemical biology 12 (2), 222-228, 2008
7972008
The redox chemistry of the Alzheimer's disease amyloid β peptide
DG Smith, R Cappai, KJ Barnham
Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (8), 1976-1990, 2007
7932007
Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease
JA Duce, A Tsatsanis, MA Cater, SA James, E Robb, K Wikhe, SL Leong, ...
Cell 142 (6), 857-867, 2010
7892010
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Aβ
PA Adlard, RA Cherny, DI Finkelstein, E Gautier, E Robb, M Cortes, ...
Neuron 59 (1), 43-55, 2008
7812008
Biological metals and metal-targeting compounds in major neurodegenerative diseases
KJ Barnham, AI Bush
Chemical Society Reviews 43 (19), 6727-6749, 2014
4852014
Cisplatin binding sites on human albumin
AI Ivanov, J Christodoulou, JA Parkinson, KJ Barnham, A Tucker, ...
Journal of Biological Chemistry 273 (24), 14721-14730, 1998
4671998
18F-THK523: a novel in vivo tau imaging ligand for Alzheimer’s disease
MT Fodero-Tavoletti, N Okamura, S Furumoto, RS Mulligan, AR Connor, ...
Brain 134 (4), 1089-1100, 2011
3982011
Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-β1-42
PJ Crouch, R Blake, JA Duce, GD Ciccotosto, QX Li, KJ Barnham, ...
Journal of Neuroscience 25 (3), 672-679, 2005
3982005
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain: a regulator of neuronal copper homeostasis
KJ Barnham, WJ McKinstry, G Multhaup, D Galatis, CJ Morton, CC Curtain, ...
Journal of Biological Chemistry 278 (19), 17401-17407, 2003
3782003
Degradation of the Alzheimer disease amyloid β-peptide by metal-dependent up-regulation of metalloprotease activity
AR White, T Du, KM Laughton, I Volitakis, RA Sharples, ME Xilinas, ...
Journal of Biological Chemistry 281 (26), 17670-17680, 2006
3522006
Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106− 126
MF Jobling, X Huang, LR Stewart, KJ Barnham, C Curtain, I Volitakis, ...
Biochemistry 40 (27), 8073-8084, 2001
3282001
Dopamine promotes α‐synuclein aggregation into SDS‐resistant soluble oligomers via a distinct folding pathway
R Cappai, SL Leck, DJ Tew, NA Williamson, DP Smith, D Galatis, ...
The FASEB journal 19 (10), 1377-1379, 2005
3242005
Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease β‐amyloid
KJ Barnham, F Haeffner, GD Ciccotosto, CC Curtain, D Tew, C Mavros, ...
The FASEB Journal 18 (12), 1427-1429, 2004
3142004
Increasing Cu bioavailability inhibits Aβ oligomers and tau phosphorylation
PJ Crouch, LW Hung, PA Adlard, M Cortes, V Lal, G Filiz, KA Perez, ...
Proceedings of the National Academy of Sciences 106 (2), 381-386, 2009
3122009
Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics
CL Masters, R Cappai, KJ Barnham, VL Villemagne
Journal of neurochemistry 97 (6), 1700-1725, 2006
3002006
Pleomorphic copper coordination by Alzheimer’s disease amyloid-β peptide
SC Drew, CJ Noble, CL Masters, GR Hanson, KJ Barnham
Journal of the American Chemical Society 131 (3), 1195-1207, 2009
2742009
Inhibition of γ‐secretase causes increased secretion of amyloid precursor protein C‐terminal fragments in association with exosomes
RA Sharples, LJ Vella, RM Nisbet, R Naylor, K Perez, KJ Barnham, ...
The FASEB Journal 22 (5), 1469-1478, 2008
2702008
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