The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 F Hayashi, KD Smith, A Ozinsky, TR Hawn, EC Yi, DR Goodlett, JK Eng, ... Nature 410 (6832), 1099-1103, 2001 | 4859 | 2001 |
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors A Ozinsky, DM Underhill, JD Fontenot, AM Hajjar, KD Smith, CB Wilson, ... Proceedings of the National Academy of Sciences 97 (25), 13766-13771, 2000 | 2840 | 2000 |
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens DM Underhill, A Ozinsky, AM Hajjar, A Stevens, CB Wilson, M Bassetti, ... Nature 401 (6755), 811-815, 1999 | 1851 | 1999 |
Phagocytosis of microbes: complexity in action DM Underhill, A Ozinsky Annual review of immunology 20 (1), 825-852, 2002 | 1489 | 2002 |
Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages DM Underhill, A Ozinsky, KD Smith, A Aderem Proceedings of the National Academy of Sciences 96 (25), 14459-14463, 1999 | 1121 | 1999 |
Pyogenic bacterial infections in humans with IRAK-4 deficiency C Picard, A Puel, M Bonnet, CL Ku, J Bustamante, K Yang, C Soudais, ... Science 299 (5615), 2076-2079, 2003 | 1098 | 2003 |
Toll-like receptors: key mediators of microbe detection DM Underhill, A Ozinsky Current opinion in immunology 14 (1), 103-110, 2002 | 1045 | 2002 |
Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism C Werts, RI Tapping, JC Mathison, TH Chuang, V Kravchenko, ... Nature immunology 2 (4), 346-352, 2001 | 959 | 2001 |
An overlapping protein-coding region in influenza A virus segment 3 modulates the host response BW Jagger, HM Wise, JC Kash, KA Walters, NM Wills, YL Xiao, ... Science 337 (6091), 199-204, 2012 | 820 | 2012 |
A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease TR Hawn, A Verbon, KD Lettinga, LP Zhao, SS Li, RJ Laws, SJ Skerrett, ... The Journal of experimental medicine 198 (10), 1563-1572, 2003 | 786 | 2003 |
Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin AM Hajjar, DS O’Mahony, A Ozinsky, DM Underhill, A Aderem, ... The Journal of Immunology 166 (1), 15-19, 2001 | 638 | 2001 |
Human TLR-7-,-8-, and-9-mediated induction of IFN-α/β and-λ is IRAK-4 dependent and redundant for protective immunity to viruses K Yang, A Puel, S Zhang, C Eidenschenk, CL Ku, A Casrouge, C Picard, ... Immunity 23 (5), 465-478, 2005 | 354 | 2005 |
Differential role of MyD88 in macrophage-mediated responses to opportunistic fungal pathogens KA Marr, S Arunmozhi Balajee, TR Hawn, A Ozinsky, U Pham, S Akira, ... Infection and immunity 71 (9), 5280-5286, 2003 | 165 | 2003 |
Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state DA Hume, DM Underhill, MJ Sweet, AO Ozinsky, FY Liew, A Aderem BMC immunology 2, 1-12, 2001 | 147 | 2001 |
Lethal synergism of 2009 pandemic H1N1 influenza virus and Streptococcus pneumoniae coinfection is associated with loss of murine lung repair responses JC Kash, KA Walters, AS Davis, A Sandouk, LM Schwartzman, BW Jagger, ... MBio 2 (5), 10.1128/mbio. 00172-11, 2011 | 142 | 2011 |
A microfluidic device for multiplexed protein detection in nano-liter volumes AH Diercks, A Ozinsky, CL Hansen, JM Spotts, DJ Rodriguez, A Aderem Analytical Biochemistry 386 (1), 30-35, 2009 | 134 | 2009 |
Co-operative induction of pro-inflammatory signaling by Toll-like receptors A Ozinsky, KD Smith, D Hume, DM Underhill Journal of endotoxin research 6 (5), 393-396, 2000 | 130 | 2000 |
Bright field microscopy as an alternative to whole cell fluorescence in automated analysis of macrophage images J Selinummi, P Ruusuvuori, I Podolsky, A Ozinsky, E Gold, O Yli-Harja, ... PloS one 4 (10), e7497, 2009 | 126 | 2009 |
Multiplexed, microfluidic molecular assay device and assay method A Diercks, A Ozinsky, C Hansen, A Aderem US Patent 8,124,015, 2012 | 115 | 2012 |
Toll-like receptor-5 and the innate immune response to bacterial flagellin KD Smith, A Ozinsky Toll-Like Receptor Family Members and Their Ligands, 93-108, 2002 | 101 | 2002 |