| Angiotensin receptor blockade attenuates cigarette smoke–induced lung injury and rescues lung architecture in mice M Podowski, C Calvi, S Metzger, K Misono, H Poonyagariyagorn, ... The Journal of clinical investigation 122 (1), 229-240, 2012 | 163 | 2012 |
| Pro-2-PAM therapy for central and peripheral cholinesterases JC DeMar, ED Clarkson, RH Ratcliffe, AJ Campbell, SG Thangavelu, ... Chemico-biological interactions 187 (1-3), 191-198, 2010 | 79 | 2010 |
| New drugs, old targets: tweaking the dopamine system to treat psychostimulant use disorders AH Newman, T Ku, CJ Jordan, A Bonifazi, ZX Xi Annual Review of Pharmacology and Toxicology 61, 609-628, 2021 | 48 | 2021 |
| Thiophene-expanded guanosine analogues of Gemcitabine Z Chen, TC Ku, KL Seley-Radtke Bioorganic & medicinal chemistry letters 25 (19), 4274-4276, 2015 | 43 | 2015 |
| Critical transition in tissue homeostasis accompanies murine lung senescence CL Calvi, M Podowski, FR D'Alessio, SL Metzger, K Misono, ... PLoS One 6 (6), e20712, 2011 | 36 | 2011 |
| VIP down‐regulates the inflammatory potential and promotes survival of dying (neural crest‐derived) corneal endothelial cells ex vivo: necrosis to apoptosis switch … SWM Koh, J Cheng, RM Dodson, CYT Ku, CJ Abbondandolo Journal of neurochemistry 109 (3), 792-806, 2009 | 31 | 2009 |
| A tropane-based ibogaine analog rescues folding-deficient SERT and DAT S Bhat, DA Guthrie, A Kasture, A El-Kasaby, J Cao, A Bonifazi, T Ku, ... ACS Pharmacology & Translational Science, 2020 | 22 | 2020 |
| Structure–Activity Relationships for a Series of (Bis (4-fluorophenyl) methyl) sulfinyl Alkyl Alicyclic Amines at the Dopamine Transporter: Functionalizing the Terminal … RD Slack, TC Ku, J Cao, JLB Giancola, A Bonifazi, CJ Loland, A Gadiano, ... Journal of medicinal chemistry 63 (5), 2343-2357, 2019 | 20 | 2019 |
| Flexibility as a Strategy in Nucleoside Antiviral Drug Design H L Peters, T C Ku, K L Seley-Radtke Current medicinal chemistry 22 (34), 3910-3921, 2015 | 18 | 2015 |
| Toward reducing hERG affinities for DAT inhibitors with a combined machine learning and molecular modeling approach KH Lee, AD Fant, J Guo, A Guan, J Jung, M Kudaibergenova, ... Journal of Chemical Information and Modeling 61 (9), 4266-4279, 2021 | 14 | 2021 |
| Bicyclic and Tricyclic “Expanded” Nucleobase Analogues of Sofosbuvir: New Scaffolds for Hepatitis C Therapies Z Chen, D Jochmans, T Ku, J Paeshuyse, J Neyts, KL Seley-Radtke ACS infectious diseases 1 (8), 357-366, 2015 | 14 | 2015 |
| Structure-activity relationships for a series of (Bis (4-fluorophenyl) methyl) sulfinylethyl-aminopiperidines and-piperidine amines at the dopamine transporter: Bioisosteric … JLB Giancola, A Bonifazi, J Cao, T Ku, AJ Haraczy, J Lam, R Rais, ... European Journal of Medicinal Chemistry, 112674, 2020 | 13 | 2020 |
| An expedient synthesis of flexible nucleosides through enzymatic glycosylation of proximal and distal fleximer bases. S Vichier-Guerre, T Ku, S Pochet, KL Seley-Radtke ChemBioChem, 2020 | 13 | 2020 |
| Novel Fluorescent Ligands Enable Single-Molecule Localization Microscopy of the Dopamine Transporter DA Guthrie, C Klein Herenbrink, MD Lycas, T Ku, A Bonifazi, BT DeVree, ... ACS Chemical Neuroscience 11 (20), 3288-3300, 2020 | 12 | 2020 |
| Synthesis of distal and proximal fleximer base analogues and evaluation in the nucleocapsid protein of HIV-1 T Ku, N Lopresti, M Shirley, M Mori, J Marchant, X Heng, M Botta, ... Bioorganic & medicinal chemistry 27 (13), 2883-2892, 2019 | 12 | 2019 |
| Oxidative mechanisms for the biotransformation of 1-methyl-1, 6-dihydropyridine-2-carbaldoxime to pralidoxime chloride FA Khan, AJ Campbell, B Hoyt, C Herdman, T Ku, S Thangavelu, ... Life sciences 89 (25-26), 911-917, 2011 | 12 | 2011 |
| Illuminating the norepinephrine transporter: fluorescent probes based on nisoxetine and talopram GA Camacho-Hernandez, A Casiraghi, D Rudin, D Luethi, TC Ku, ... RSC Medicinal Chemistry, 2021 | 10 | 2021 |
| Synthetic Approaches to the Fleximer Class of Nucleosides–A Historic Perspective TC Ku, K Seley-Radtke Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives, 195-235, 2019 | 2 | 2019 |
| Discovery of non-oxime reactivators using an in silico pharmacophore model of reactivators for tabun-inhibited acetylcholinesterase AK Bhattacharjee, E Marek, HT Le, T Ku, RK Gordon The FASEB Journal 25 (1_supplement), 962.1-962.1, 2011 | 1 | 2011 |
| Cover Feature: An Expedient Synthesis of Flexible Nucleosides through Enzymatic Glycosylation of Proximal and Distal Fleximer Bases (ChemBioChem 10/2020) S Vichier‐Guerre, TC Ku, S Pochet, KL Seley‐Radtke ChemBioChem 21 (10), 1385-1385, 2020 | | 2020 |
