Balancing Cationic and Hydrophobic Content of PEGylated siRNA Polyplexes Enhances Endosome Escape, Stability, Blood Circulation Time, and Bioactivity in Vivo CE Nelson, JR Kintzing, A Hanna, JM Shannon, MK Gupta, CL Duvall ACS nano 7 (10), 8870-8880, 2013 | 342 | 2013 |
Hedgehog signaling: modulation of cancer properies and tumor mircroenvironment A Hanna, LA Shevde Molecular cancer 15, 1-14, 2016 | 238 | 2016 |
T cells specific for α-myosin drive immunotherapy-related myocarditis ML Axelrod, WC Meijers, EM Screever, J Qin, MG Carroll, X Sun, ... Nature 611 (7937), 818-826, 2022 | 126 | 2022 |
Inhibition of Hedgehog signaling reprograms the dysfunctional immune microenvironment in breast cancer A Hanna, BJ Metge, SK Bailey, D Chen, DS Chandrashekar, ... Oncoimmunology 8 (3), 1548241, 2019 | 73 | 2019 |
Hedgehog signaling regulates metabolism and polarization of mammary tumor-associated macrophages DC Hinshaw, A Hanna, T Lama-Sherpa, B Metge, SC Kammerud, ... Cancer research 81 (21), 5425-5437, 2021 | 64 | 2021 |
The impact of hedgehog signaling pathway on DNA repair mechanisms in human cancer E Meng, A Hanna, RS Samant, LA Shevde Cancers 7 (3), 1333-1348, 2015 | 50 | 2015 |
Breast cancer resistance mechanisms: challenges to immunotherapy A Hanna, JM Balko Breast cancer research and treatment 190, 5-17, 2021 | 23 | 2021 |
STING-activating nanoparticles normalize the vascular-immune interface to potentiate cancer immunotherapy L Wang-Bishop, BR Kimmel, VM Ngwa, MZ Madden, JJ Baljon, ... Science immunology 8 (83), eadd1153, 2023 | 22 | 2023 |
O-GlcNAcylation of GLI transcription factors in hyperglycemic conditions augments Hedgehog activity S Das, SK Bailey, BJ Metge, A Hanna, DC Hinshaw, M Mota, ... Laboratory investigation 99 (2), 260-270, 2019 | 22 | 2019 |
Pharmacological activation of cGAS for cancer immunotherapy KM Garland, JC Rosch, CS Carson, L Wang-Bishop, A Hanna, S Sevimli, ... Frontiers in Immunology 12, 753472, 2021 | 19 | 2021 |
Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling S Das, WP Jackson, JK Prasain, A Hanna, SK Bailey, JA Tucker, S Bae, ... Scientific Reports 7 (1), 40773, 2017 | 8 | 2017 |
NKG2A Is a Therapeutic Vulnerability in Immunotherapy Resistant MHC-I Heterogeneous Triple-Negative Breast Cancer BC Taylor, X Sun, PI Gonzalez-Ericsson, V Sanchez, ME Sanders, ... Cancer Discovery 14 (2), 290-307, 2024 | 5 | 2024 |
Combined Dusp4 and p53 loss with Dbf4 amplification drives tumorigenesis via cell cycle restriction and replication stress escape in breast cancer A Hanna, MJ Nixon, MV Estrada, V Sanchez, Q Sheng, SR Opalenik, ... Breast Cancer Research 24 (1), 51, 2022 | 5 | 2022 |
Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8+ T cells in a mouse model of mammary carcinoma DC Hinshaw, CA Swain, D Chen, A Hanna, PA Molina, CL Maynard, ... Laboratory Investigation 102 (11), 1236-1244, 2022 | 4 | 2022 |
No rest for the wicked: Tumor cell senescence reshapes the immune microenvironment A Hanna, JM Balko Cancer Cell 41 (5), 831-833, 2023 | 1 | 2023 |
Programable Albumin-Hitchhiking Nanobodies Enhance the Delivery of STING Agonists to Potentiate Cancer Immunotherapy J Wilson, B Kimmel, K Arora, N Chada, V Bharti, A Kwiatkowski, ... Research Square, 2024 | | 2024 |
Epithelial Expressed B7-H4 Drives Differential Immunotherapy Response in Murine and Human Breast Cancer EC Wescott, X Sun, P Gonzalez-Ericsson, A Hanna, BC Taylor, ... Cancer Research Communications 4 (4), 1120-1134, 2024 | | 2024 |
1002 Intratumor heterogeneity in MHC-I expression drives immunotherapy resistance and exposes NKG2A as a therapeutic target in breast cancer BC Taylor, X Sun, PG Ericsson, V Sanchez, M Sanders, E Wescott, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
538 Longitudinal transcriptomic local and peripheral changes are associated with immunotherapy resistance in murine model of triple negative breast cancer A Hanna, X Sun, Q Sheng, PG Ericsson, EN Tran, S Opalenik, JM Balko Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
Longitudinal local and peripheral immunologic changes associated with PD-L1 response in a murine breast cancer model A Hanna, X Sun, E Tran, Q Sheng, BC Taylor, SR Opalenik, JM Balko Cancer Research 83 (7_Supplement), 4152-4152, 2023 | | 2023 |