| Structure of the adenosine A1 receptor reveals the basis for subtype selectivity A Glukhova, DM Thal, AT Nguyen, EA Vecchio, M Jörg, PJ Scammells, ... Cell 168 (5), 867-877. e13, 2017 | 292 | 2017 |
| Synthesis and Pharmacological Evaluation of Dual Acting Ligands Targeting the Adenosine A2A and Dopamine D2 Receptors for the Potential Treatment of … M Jörg, LT May, FS Mak, KCK Lee, ND Miller, PJ Scammells, ... Journal of medicinal chemistry 58 (2), 718-738, 2015 | 60 | 2015 |
| The dopamine D2 and adenosine A2A receptors: past, present and future trends for the treatment of Parkinson's disease M Jorg, PJ Scammells, B Capuano Current medicinal chemistry 21 (27), 3188-3210, 2014 | 41 | 2014 |
| 4-Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of the M1 Muscarinic Acetylcholine Receptor SN Mistry, M Jörg, H Lim, NB Vinh, PM Sexton, B Capuano, ... Journal of Medicinal Chemistry 59 (1), 388-409, 2016 | 37 | 2016 |
| The dopamine D2 receptor dimer and its interaction with homobivalent antagonists: homology modeling, docking and molecular dynamics AA Kaczor, M Jörg, B Capuano Journal of Molecular Modeling 22, 1-14, 2016 | 34 | 2016 |
| A Structure–Activity Relationship Study of Bitopic N6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists L Aurelio, JA Baltos, L Ford, ATN Nguyen, M Jorg, SM Devine, C Valant, ... Journal of medicinal chemistry 61 (5), 2087-2103, 2018 | 28 | 2018 |
| Novel adenosine A2A receptor ligands: a synthetic, functional and computational investigation of selected literature adenosine A2A receptor antagonists for extending into … M Jörg, J Shonberg, FS Mak, ND Miller, E Yuriev, PJ Scammells, ... Bioorganic & medicinal chemistry letters 23 (11), 3427-3433, 2013 | 28 | 2013 |
| Probing the binding site of novel selective positive allosteric modulators at the M1 muscarinic acetylcholine receptor E Khajehali, C Valant, M Jörg, AB Tobin, PJ Conn, CW Lindsley, ... Biochemical pharmacology 154, 243-254, 2018 | 27 | 2018 |
| Novel Irreversible Agonists Acting at the A1 Adenosine Receptor M Jorg, A Glukhova, A Abdul-Ridha, EA Vecchio, ATN Nguyen, ... Journal of Medicinal Chemistry 59 (24), 11182-11194, 2016 | 27 | 2016 |
| Investigation of novel ropinirole analogues: synthesis, pharmacological evaluation and computational analysis of dopamine D 2 receptor functionalized congeners and homobivalent … M Jörg, AA Kaczor, FS Mak, KCK Lee, A Poso, ND Miller, PJ Scammells, ... MedChemComm 5 (7), 891-898, 2014 | 27 | 2014 |
| Guidelines for the Synthesis of Small‐Molecule Irreversible Probes Targeting G Protein‐Coupled Receptors M Jörg, PJ Scammells ChemMedChem 11 (14), 1488-1498, 2016 | 23 | 2016 |
| Probe dependence of allosteric enhancers on the binding affinity of adenosine A1‐receptor agonists at rat and human A1‐receptors measured using NanoBRET SL Cooper, M Soave, M Jörg, PJ Scammells, J Woolard, SJ Hill British Journal of Pharmacology 176 (7), 864-878, 2019 | 22 | 2019 |
| Synthesis, molecular structure, NMR spectroscopic and computational analysis of a selective adenosine A2A antagonist, ZM 241385 M Jörg, M Agostino, E Yuriev, FS Mak, ND Miller, JM White, PJ Scammells, ... Structural Chemistry 24, 1241-1251, 2013 | 22 | 2013 |
| Novel adenosine A2A receptor ligands: a synthetic, functional and computational investigation of selected literature adenosine A2A receptor antagonists for extending into … MT Jorg, J Shonberg, FS Mak, ND Miller, E Yuriev, PJ Scammells, ... Bioorganic and Medicinal Chemistry Letters 23 (11), 3427-3433, 2013 | 20 | 2013 |
| Synthesis and Pharmacological Evaluation of Heterocyclic Carboxamides: Positive Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor with Weak … JCC Dallagnol, E Khajehali, ET Van Der Westhuizen, M Jörg, C Valant, ... Journal of Medicinal Chemistry 61 (7), 2875-2894, 2018 | 17 | 2018 |
| Novel Fused Arylpyrimidinone Based Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor SN Mistry, H Lim, M Jörg, B Capuano, A Christopoulos, JR Lane, ... ACS Chemical Neuroscience 7 (5), 647-661, 2016 | 14 | 2016 |
| Assessment of the molecular mechanisms of action of novel 4-Phenylpyridine-2-one and 6-Phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptors ET van der Westhuizen, A Spathis, E Khajehali, M Jörg, SN Mistry, ... Molecular Pharmacology 94 (1), 770-783, 2018 | 12 | 2018 |
| The right tools for the job: The central role for next generation chemical probes and chemistry-based target deconvolution methods in phenotypic drug discovery M Jörg, KS Madden RSC Medicinal Chemistry 12 (5), 646-665, 2021 | 10 | 2021 |
| 6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity M Jorg, ET van der Westhuizen, E Khajehali, WAC Burger, JM White, ... ACS Chemical Neuroscience 10 (3), 1099-1114, 2018 | 9 | 2018 |
| New small molecule fluorescent probes for G protein-coupled receptors: valuable tools for drug discovery JW Conner, DP Poole, M Jörg, NA Veldhuis Future Medicinal Chemistry 13 (1), 63-90, 2021 | 7 | 2021 |
