The ensemble nature of allostery HN Motlagh, JO Wrabl, J Li, VJ Hilser Nature 508 (7496), 331-339, 2014 | 1244 | 2014 |
The heat capacity of proteins J Gomez, VJ Hilser, D Xie, E Freire Proteins: Structure, Function, and Bioinformatics 22 (4), 404-412, 1995 | 542 | 1995 |
Intrinsic disorder as a mechanism to optimize allosteric coupling in proteins VJ Hilser, EB Thompson Proceedings of the National Academy of Sciences 104 (20), 8311-8315, 2007 | 464 | 2007 |
The magnitude of the backbone conformational entropy change in protein folding JA D'aquino, J Gómez, VJ Hilser, KH Lee, LM Amzel, E Freire Proteins: Structure, Function, and Bioinformatics 25 (2), 143-156, 1996 | 363 | 1996 |
Structural and energetic basis of allostery VJ Hilser, JO Wrabl, HN Motlagh Annual review of biophysics 41, 585-609, 2012 | 332 | 2012 |
Structure-based calculation of the equilibrium folding pathway of proteins. Correlation with hydrogen exchange protection factors VJ Hilser, E Freire Journal of molecular biology 262 (5), 756-772, 1996 | 328 | 1996 |
Allostery in its many disguises: from theory to applications SJ Wodak, E Paci, NV Dokholyan, IN Berezovsky, A Horovitz, J Li, ... Structure 27 (4), 566-578, 2019 | 307 | 2019 |
Binding sites in Escherichia coli dihydrofolate reductase communicate by modulating the conformational ensemble H Pan, JC Lee, VJ Hilser Proceedings of the National Academy of Sciences 97 (22), 12020-12025, 2000 | 259 | 2000 |
The structural distribution of cooperative interactions in proteins: analysis of the native state ensemble VJ Hilser, D Dowdy, TG Oas, E Freire Proceedings of the National Academy of Sciences 95 (17), 9903-9908, 1998 | 252 | 1998 |
A statistical thermodynamic model of the protein ensemble VJ Hilser, B García-Moreno E, TG Oas, G Kapp, ST Whitten Chemical reviews 106 (5), 1545-1558, 2006 | 233 | 2006 |
Local conformational fluctuations can modulate the coupling between proton binding and global structural transitions in proteins ST Whitten, B García-Moreno E, VJ Hilser Proceedings of the National Academy of Sciences 102 (12), 4282-4287, 2005 | 191 | 2005 |
The enthalpy change in protein folding and binding: Refinement of parameters for structure‐based calculations VJ Hilser, J Gómez, E Freire Proteins: Structure, Function, and Bioinformatics 26 (2), 123-133, 1996 | 182 | 1996 |
Rational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteins TP Schrank, DW Bolen, VJ Hilser Proceedings of the National Academy of Sciences 106 (40), 16984-16989, 2009 | 178 | 2009 |
Dynamic allostery can drive cold adaptation in enzymes HG Saavedra, JO Wrabl, JA Anderson, J Li, VJ Hilser Nature 558 (7709), 324-328, 2018 | 176 | 2018 |
Direct access to the cooperative substructure of proteins and the protein ensemble via cold denaturation CR Babu, VJ Hilser, AJ Wand Nature structural & molecular biology 11 (4), 352-357, 2004 | 166 | 2004 |
An ensemble view of allostery VJ Hilser Science 327 (5966), 653-654, 2010 | 140 | 2010 |
The role of protein conformational fluctuations in allostery, function, and evolution JO Wrabl, J Gu, T Liu, TP Schrank, ST Whitten, VJ Hilser Biophysical chemistry 159 (1), 129-141, 2011 | 128 | 2011 |
Agonism/antagonism switching in allosteric ensembles HN Motlagh, VJ Hilser Proceedings of the National Academy of Sciences 109 (11), 4134-4139, 2012 | 118 | 2012 |
Coupled motion in proteins revealed by pressure perturbation Y Fu, V Kasinath, VR Moorman, NV Nucci, VJ Hilser, AJ Wand Journal of the American Chemical Society 134 (20), 8543-8550, 2012 | 104 | 2012 |
Predicting the equilibrium protein folding pathway: structure‐based analysis of staphylococcal nuclease VJ Hilser, E Freire Proteins: Structure, Function, and Bioinformatics 27 (2), 171-183, 1997 | 102 | 1997 |