The roles of ROS in cancer heterogeneity and therapy PL de Sá Junior, DAD Câmara, AS Porcacchia, PMM Fonseca, SD Jorge, ... Oxidative medicine and cellular longevity 2017 (1), 2467940, 2017 | 258 | 2017 |
Design, synthesis, antimicrobial activity and molecular modeling studies of novel benzofuroxan derivatives against Staphylococcus aureus SD Jorge, A Masunari, CO Rangel-Yagui, KFM Pasqualoto, LC Tavares Bioorganic & medicinal chemistry 17 (8), 3028-3036, 2009 | 72 | 2009 |
Synthesis, molecular modeling and preliminary biological evaluation of a set of 3-acetyl-2, 5-disubstituted-2, 3-dihydro-1, 3, 4-oxadiazole as potential antibacterial, anti … M Ishii, SD Jorge, AA de Oliveira, F Palace-Berl, IY Sonehara, ... Bioorganic & medicinal chemistry 19 (21), 6292-6301, 2011 | 59 | 2011 |
Exploring 5-nitrofuran derivatives against nosocomial pathogens: synthesis, antimicrobial activity and chemometric analysis RR Zorzi, SD Jorge, F Palace-Berl, KFM Pasqualoto, L de Sá Bortolozzo, ... Bioorganic & medicinal chemistry 22 (10), 2844-2854, 2014 | 40 | 2014 |
Novel benzofuroxan derivatives against multidrug-resistant Staphylococcus aureus strains: Design using Topliss’ decision tree, synthesis and biological assay SD Jorge, F Palace-Berl, A Masunari, CA Cechinel, M Ishii, ... Bioorganic & medicinal chemistry 19 (16), 5031-5038, 2011 | 40 | 2011 |
5-Nitro-2-furfuriliden derivatives as potential anti-Trypanosoma cruzi agents: Design, synthesis, bioactivity evaluation, cytotoxicity and exploratory data analysis F Palace-Berl, SD Jorge, KFM Pasqualoto, AK Ferreira, DA Maria, ... Bioorganic & medicinal chemistry 21 (17), 5395-5406, 2013 | 33 | 2013 |
Designing and exploring active N′-[(5-nitrofuran-2-yl) methylene] substituted hydrazides against three Trypanosoma cruzi strains more prevalent in Chagas disease patients F Palace-Berl, KFM Pasqualoto, SD Jorge, B Zingales, RR Zorzi, MN Silva, ... European journal of medicinal chemistry 96, 330-339, 2015 | 29 | 2015 |
Ligand-based design, synthesis, and experimental evaluation of novel benzofuroxan derivatives as anti-Trypanosoma cruzi agents SD Jorge, F Palace-Berl, KFM Pasqualoto, M Ishii, AK Ferreira, CM Berra, ... European journal of medicinal chemistry 64, 200-214, 2013 | 29 | 2013 |
Molecular modeling studies and in vitro bioactivity evaluation of a set of novel 5-nitro-heterocyclic derivatives as anti-T. cruzi agents FR Paula, SD Jorge, LV de Almeida, KFM Pasqualoto, LC Tavares Bioorganic & medicinal chemistry 17 (7), 2673-2679, 2009 | 29 | 2009 |
Benzofuroxan derivatives N-Br and NI induce intrinsic apoptosis in melanoma cells by regulating AKT/BIM signaling and display anti metastatic activity in vivo CF Farias, MH Massaoka, N Girola, RA Azevedo, AK Ferreira, SD Jorge, ... BMC cancer 15, 1-11, 2015 | 18 | 2015 |
Preliminary in vitro evaluation of N′-(benzofuroxan-5-yl) methylene benzohydrazide derivatives as potential anti-Trypanosoma cruzi agents SD Jorge, M Ishii, F Palace-Berl, AK Ferreira, PL de Sa Junior, ... MedChemComm 3 (7), 824-828, 2012 | 17 | 2012 |
BFD-22 a new potential inhibitor of BRAF inhibits the metastasis of B16F10 melanoma cells and simultaneously increased the tumor immunogenicity AK Ferreira, KFM Pasqualoto, FAE Kruyt, F Palace-Berl, RA Azevedo, ... Toxicology and Applied Pharmacology 295, 56-67, 2016 | 14 | 2016 |
Synergistic anti-tumor effects of the combination of a benzofuroxan derivate and sorafenib on NCI-H460 human large cell lung carcinoma cells SF Teixeira, RA de Azevedo, MAC Salomon, SD Jorge, D Levy, ... Biomedicine & Pharmacotherapy 68 (8), 1015-1022, 2014 | 10 | 2014 |
Phosphoethanolamine induces caspase-independent cell death by reducing the expression of C-RAF and inhibits tumor growth in human melanoma model LI Mambelli, SF Teixeira, SD Jorge, B Kawamura, R Meneguelo, ... Biomedicine & Pharmacotherapy 103, 18-28, 2018 | 7 | 2018 |
Edelfosine: An antitumor drug prototype SF Teixeira, CP Rodrigues, CJS Costa, TN Pettinati, RA de Azevedo, ... Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018 | 7 | 2018 |
Evaluation of cytotoxic effect of the combination of a pyridinyl carboxamide derivative and oxaliplatin on NCI-H1299 human non-small cell lung carcinoma cells SF Teixeira, RA de Azevedo, AC Silva, RC Braga, SD Jorge, JAM Barbuto, ... Biomedicine & Pharmacotherapy 84, 1019-1028, 2016 | 5 | 2016 |
Síntese e avaliação da atividade antibacteriana de derivados 5-metilsulfonil-2-tiofilidênicos e de derivados 5 (6)-benzofuroxânicos frente a cepas padrão e multi-resistente de … SD Jorge Universidade de São Paulo, 2007 | 4 | 2007 |
Topliss decision-tree approach applied in the design of new benzofuroxan derivatives with antimicrobial activity against multidrug-resistant Staphylococcus aureus strains FP Berl, A Masunari, SD Jorge, CA Cechinel, M Ishii, LC Tavares Brazilian Journal of Pharmaceutical Sciences 45, 67, 2009 | 2 | 2009 |
Integrative modeling, molecular mechanics, and molecular dynamics evaluation of genomics variants in KMT2C (MLL3), a gene involved in Kleefstra Syndrome Type 2 SD Jorge, YI Chi, TM de Assuncao, AJ Mathison, B Volkman, B Smith, ... The FASEB Journal 36, 2022 | 1 | 2022 |
Deep computational phenotyping of genomic variants impacting the SET domain of KMT2C reveal molecular mechanisms for their dysfunction SD Jorge, YI Chi, JL Mazaba, N Haque, J Wagenknecht, BC Smith, ... Frontiers in Genetics 14, 1291307, 2023 | | 2023 |