Regulating gene drives KA Oye, K Esvelt, E Appleton, F Catteruccia, G Church, T Kuiken, ... Science 345 (6197), 626-628, 2014 | 432 | 2014 |
A comprehensive library of human transcription factors for cell fate engineering AHM Ng, P Khoshakhlagh, JE Rojo Arias, G Pasquini, K Wang, A Swiersy, ... Nature biotechnology 39 (4), 510-519, 2021 | 138 | 2021 |
An end-to-end workflow for engineering of biological networks from high-level specifications J Beal, R Weiss, D Densmore, A Adler, E Appleton, J Babb, S Bhatia, ... ACS synthetic biology 1 (8), 317-331, 2012 | 111 | 2012 |
Design automation in synthetic biology E Appleton, C Madsen, N Roehner, D Densmore Cold Spring Harbor perspectives in biology 9 (4), a023978, 2017 | 90 | 2017 |
Interactive assembly algorithms for molecular cloning E Appleton, J Tao, T Haddock, D Densmore Nature methods 11 (6), 657-662, 2014 | 71 | 2014 |
Building biosecurity for synthetic biology BD Trump, SE Galaitsi, E Appleton, DA Bleijs, MV Florin, JD Gollihar, ... Molecular systems biology 16 (7), e9723, 2020 | 40 | 2020 |
Needs and opportunities in bio-design automation: four areas for focus E Appleton, D Densmore, C Madsen, N Roehner Current Opinion in Chemical Biology 40, 111-118, 2017 | 36 | 2017 |
A computer-guided design tool to increase the efficiency of cellular conversions S Jung, E Appleton, M Ali, GM Church, A Del Sol Nature communications 12 (1), 1659, 2021 | 30 | 2021 |
Cell therapy strategies for COVID-19: Current approaches and potential applications MM Zaki, E Lesha, K Said, K Kiaee, L Robinson-McCarthy, H George, ... Science advances 7 (33), eabg5995, 2021 | 25 | 2021 |
helixCAM: a platform for programmable cellular assembly in bacteria and human cells G Chao, TM Wannier, C Gutierrez, NC Borders, E Appleton, A Chadha, ... Cell 185 (19), 3551-3567. e39, 2022 | 22 | 2022 |
Synthetic auxotrophy remains stable after continuous evolution and in coculture with mammalian cells AM Kunjapur, MG Napolitano, E Hysolli, K Noguera, EM Appleton, ... Science Advances 7 (27), eabf5851, 2021 | 20 | 2021 |
Suprathermal electron flux peaks at stream interfaces: Signature of solar wind dynamics or tracer for open magnetic flux transport on the Sun? NU Crooker, EM Appleton, NA Schwadron, MJ Owens Journal of Geophysical Research: Space Physics 115 (A11), 2010 | 19 | 2010 |
Targeted intracellular delivery of Cas13 and Cas9 nucleases using bacterial toxin-based platforms S Tian, Y Liu, E Appleton, H Wang, GM Church, M Dong Cell reports 38 (10), 2022 | 15 | 2022 |
An end-to-end workflow for engineering of biological networks from high-level specifications ACS Synth J Beal, R Weiss, D Densmore, A Adler, E Appleton, J Babb, S Bhatia, ... Biol 1 (8), 317331, 2012 | 13 | 2012 |
Designing safety policies to meet evolving needs: iGEM as a testbed for proactive and adaptive risk management J McNamara, SBY Lightfoot, K Drinkwater, E Appleton, K Oye ACS Synthetic Biology 3 (12), 983-985, 2014 | 12 | 2014 |
Experimentally driven verification of synthetic biological circuits B Yordanov, E Appleton, R Ganguly, EA Gol, SB Carr, S Bhatia, ... 2012 Design, Automation & Test in Europe Conference & Exhibition (DATE), 236-241, 2012 | 7 | 2012 |
Genetic design automation for autonomous formation of multicellular shapes from a single cell progenitor E Appleton, N Mehdipour, T Daifuku, D Briers, I Haghighi, M Moret, ... bioRxiv, 807107, 2019 | 5 | 2019 |
Owl: Electronic Datasheet Generator E Appleton, J Tao, FC Wheatley, DH Desai, TM Lozanoski, PD Shah, ... ACS Synthetic Biology 3 (12), 966-968, 2014 | 5 | 2014 |
Machine-guided cell-fate engineering E Appleton, J Tao, G Fonseca, S Liu, C Glass, G Church bioRxiv, 2022.10. 14.512279, 2022 | 3 | 2022 |
Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC S Liu, L Li, F Zhang, B van Sambeek, E Appleton, AHM Ng, ... BioRxiv, 2022.06. 03.494617, 2022 | 3 | 2022 |