Physiologically based pharmacokinetic model qualification and reporting procedures for regulatory submissions: a consortium perspective M Shebley, P Sandhu, A Emami Riedmaier, M Jamei, R Narayanan, ... Clinical Pharmacology & Therapeutics 104 (1), 88-110, 2018 | 312 | 2018 |
Physiologically based pharmacokinetic modeling: methodology, applications, and limitations with a focus on its role in pediatric drug development F Khalil, S Läer BioMed Research International 2011 (1), 907461, 2011 | 169 | 2011 |
Physiologically based pharmacokinetic models in the prediction of oral drug exposure over the entire pediatric age range—sotalol as a model drug F Khalil, S Läer The AAPS journal 16, 226-239, 2014 | 91 | 2014 |
A physiologically based pharmacokinetic drug–disease model to predict carvedilol exposure in adult and Paediatric heart failure patients by incorporating pathophysiological … MF Rasool, F Khalil, S Läer Clinical pharmacokinetics 54, 943-962, 2015 | 49 | 2015 |
Optimizing the clinical use of carvedilol in liver cirrhosis using a physiologically based pharmacokinetic modeling approach MF Rasool, F Khalil, S Läer European journal of drug metabolism and pharmacokinetics 42, 383-396, 2017 | 36 | 2017 |
Predicting stereoselective disposition of carvedilol in adult and pediatric chronic heart failure patients by incorporating pathophysiological changes in organ blood flows–a … MF Rasool, F Khalil, S Läer Drug Metabolism and Disposition 44 (7), 1103-1115, 2016 | 19 | 2016 |
Pharmacotherapeutic management of paediatric heart failure and ACE-I use patterns: a European survey CC Díez, F Khalil, H Schwender, M Dalinghaus, I Jovanovic, N Makowski, ... BMJ paediatrics open 3 (1), 2019 | 14 | 2019 |
Relative bioavailability of enalapril administered as orodispersible minitablets in healthy adults A Van Hecken, BB Burckhardt, F Khalil, J de Hoon, I Klingmann, ... Clinical Pharmacology in Drug Development 9 (2), 203-213, 2020 | 9 | 2020 |
Question 1: How safe are ACE inhibitors for heart failure in children? M Van Der Meulen, M Dalinghaus, M Burch, A Szatmari, CC Diez, F Khalil, ... Archives of Disease in Childhood 103 (1), 106-109, 2018 | 7 | 2018 |
Population pharmacokinetics of tapentadol in children from birth to< 18 years old F Khalil, SL Choi, E Watson, TM Tzschentke, C Lefeber, M Eerdekens, ... Journal of Pain Research, 3107-3123, 2020 | 6 | 2020 |
Outcomes of the pediatric development plan of tapentadol M Eerdekens, T Radic, M Sohns, F Khalil, B Bulawa, C Elling Journal of Pain Research, 249-261, 2021 | 4 | 2021 |
Simultaneous Semi-Mechanistic Population Pharmacokinetic Modeling Analysis of Enalapril and Enalaprilat Serum and Urine Concentrations From Child Appropriate Orodispersible … M Faisal, W Cawello, BB Burckhardt, J De Hoon, S Laer, ... Frontiers in Pediatrics 7, 281, 2019 | 4 | 2019 |
Pharmacotherapy in paediatric heart failure: a Delphi process CC Díez, F Khalil, N Makowski, H Schwender, I Jovanovic, M Dalinghaus, ... Cardiology in the Young 29 (7), 869-876, 2019 | 1 | 2019 |
Multiple Dose Pharmacokinetics of Tapentadol Oral Solution for the Treatment of Moderate to Severe Acute Pain in Children Aged 2 to< 7 Years R Jończyk, C Beuter, B Bulawa, S Buller, C Eibl, C Elling, M Gautrois, ... Journal of Pain Research, 3103-3114, 2022 | | 2022 |
PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS FOR ADULT AND PAEDIATRIC CHRONIC HEART FAILURE PATIENTS USING THE EXAMPLE OF CARVEDILOL TREATED PATIENTS M Rasool, F Khalil, S Läer Archives of Disease in Childhood 101 (1), e1-e1, 2016 | | 2016 |
DESIGN OF A EUROPEAN SURVEY ON THE PHARMACOLOGICAL MANAGEMENT OF PAEDIATRIC HEART FAILURE CC Díez, F Khalil, M Dalinghaus, M van der Meulen, S de Wildt, ... Archives of Disease in Childhood 101 (1), e1-e1, 2016 | | 2016 |
SAFETY OF ACE INHIBITORS IN CHILDREN WITH HEART FAILURE M van der Meulen, S Läer, C Castro, F Khalil, S de Wildt, M Dalinghaus, ... Archives of Disease in Childhood 101 (1), e1-e1, 2016 | | 2016 |
Author’s Reply to Zheng et al.: A Physiologically Based Pharmacokinetic Drug–Disease Model to Predict Carvedilol Exposure in Adult and Paediatric Heart Failure Patients by … MF Rasool, F Khalil, S Läer Clinical pharmacokinetics 55, 139-141, 2016 | | 2016 |
Innovative tools in the individualized medical therapy for children with heart muscle disease F Khalil, R Lüpken, S Läer, D Bernstein Progress in Pediatric Cardiology 39 (1), 37-41, 2015 | | 2015 |
Modelling and Simulation to Support Neonatal Clinical Trials F Khalil, S Läer Neonatal Pharmacology and Nutrition Update 18, 58-69, 2015 | | 2015 |