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Feras Khalil
Feras Khalil
Grünenthal GmbH
在 grunenthal.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Physiologically based pharmacokinetic model qualification and reporting procedures for regulatory submissions: a consortium perspective
M Shebley, P Sandhu, A Emami Riedmaier, M Jamei, R Narayanan, ...
Clinical Pharmacology & Therapeutics 104 (1), 88-110, 2018
3122018
Physiologically based pharmacokinetic modeling: methodology, applications, and limitations with a focus on its role in pediatric drug development
F Khalil, S Läer
BioMed Research International 2011 (1), 907461, 2011
1692011
Physiologically based pharmacokinetic models in the prediction of oral drug exposure over the entire pediatric age range—sotalol as a model drug
F Khalil, S Läer
The AAPS journal 16, 226-239, 2014
912014
A physiologically based pharmacokinetic drug–disease model to predict carvedilol exposure in adult and Paediatric heart failure patients by incorporating pathophysiological …
MF Rasool, F Khalil, S Läer
Clinical pharmacokinetics 54, 943-962, 2015
492015
Optimizing the clinical use of carvedilol in liver cirrhosis using a physiologically based pharmacokinetic modeling approach
MF Rasool, F Khalil, S Läer
European journal of drug metabolism and pharmacokinetics 42, 383-396, 2017
362017
Predicting stereoselective disposition of carvedilol in adult and pediatric chronic heart failure patients by incorporating pathophysiological changes in organ blood flows–a …
MF Rasool, F Khalil, S Läer
Drug Metabolism and Disposition 44 (7), 1103-1115, 2016
192016
Pharmacotherapeutic management of paediatric heart failure and ACE-I use patterns: a European survey
CC Díez, F Khalil, H Schwender, M Dalinghaus, I Jovanovic, N Makowski, ...
BMJ paediatrics open 3 (1), 2019
142019
Relative bioavailability of enalapril administered as orodispersible minitablets in healthy adults
A Van Hecken, BB Burckhardt, F Khalil, J de Hoon, I Klingmann, ...
Clinical Pharmacology in Drug Development 9 (2), 203-213, 2020
92020
Question 1: How safe are ACE inhibitors for heart failure in children?
M Van Der Meulen, M Dalinghaus, M Burch, A Szatmari, CC Diez, F Khalil, ...
Archives of Disease in Childhood 103 (1), 106-109, 2018
72018
Population pharmacokinetics of tapentadol in children from birth to< 18 years old
F Khalil, SL Choi, E Watson, TM Tzschentke, C Lefeber, M Eerdekens, ...
Journal of Pain Research, 3107-3123, 2020
62020
Outcomes of the pediatric development plan of tapentadol
M Eerdekens, T Radic, M Sohns, F Khalil, B Bulawa, C Elling
Journal of Pain Research, 249-261, 2021
42021
Simultaneous Semi-Mechanistic Population Pharmacokinetic Modeling Analysis of Enalapril and Enalaprilat Serum and Urine Concentrations From Child Appropriate Orodispersible …
M Faisal, W Cawello, BB Burckhardt, J De Hoon, S Laer, ...
Frontiers in Pediatrics 7, 281, 2019
42019
Pharmacotherapy in paediatric heart failure: a Delphi process
CC Díez, F Khalil, N Makowski, H Schwender, I Jovanovic, M Dalinghaus, ...
Cardiology in the Young 29 (7), 869-876, 2019
12019
Multiple Dose Pharmacokinetics of Tapentadol Oral Solution for the Treatment of Moderate to Severe Acute Pain in Children Aged 2 to< 7 Years
R Jończyk, C Beuter, B Bulawa, S Buller, C Eibl, C Elling, M Gautrois, ...
Journal of Pain Research, 3103-3114, 2022
2022
PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS FOR ADULT AND PAEDIATRIC CHRONIC HEART FAILURE PATIENTS USING THE EXAMPLE OF CARVEDILOL TREATED PATIENTS
M Rasool, F Khalil, S Läer
Archives of Disease in Childhood 101 (1), e1-e1, 2016
2016
DESIGN OF A EUROPEAN SURVEY ON THE PHARMACOLOGICAL MANAGEMENT OF PAEDIATRIC HEART FAILURE
CC Díez, F Khalil, M Dalinghaus, M van der Meulen, S de Wildt, ...
Archives of Disease in Childhood 101 (1), e1-e1, 2016
2016
SAFETY OF ACE INHIBITORS IN CHILDREN WITH HEART FAILURE
M van der Meulen, S Läer, C Castro, F Khalil, S de Wildt, M Dalinghaus, ...
Archives of Disease in Childhood 101 (1), e1-e1, 2016
2016
Author’s Reply to Zheng et al.: A Physiologically Based Pharmacokinetic Drug–Disease Model to Predict Carvedilol Exposure in Adult and Paediatric Heart Failure Patients by …
MF Rasool, F Khalil, S Läer
Clinical pharmacokinetics 55, 139-141, 2016
2016
Innovative tools in the individualized medical therapy for children with heart muscle disease
F Khalil, R Lüpken, S Läer, D Bernstein
Progress in Pediatric Cardiology 39 (1), 37-41, 2015
2015
Modelling and Simulation to Support Neonatal Clinical Trials
F Khalil, S Läer
Neonatal Pharmacology and Nutrition Update 18, 58-69, 2015
2015
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