IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation KM Lin, W Hu, TD Troutman, M Jennings, T Brewer, X Li, S Nanda, ... Proceedings of the National Academy of Sciences 111 (2), 775-780, 2014 | 317 | 2014 |
Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt TD Troutman, W Hu, S Fulenchek, T Yamazaki, T Kurosaki, JF Bazan, ... Proceedings of the National Academy of Sciences 109 (1), 273-278, 2012 | 211 | 2012 |
Priming microenvironments dictate cytokine requirements for T helper 17 cell lineage commitment W Hu, TD Troutman, R Edukulla, C Pasare Immunity 35 (6), 1010-1022, 2011 | 137 | 2011 |
Location, location, location: tissue-specific regulation of immune responses W Hu, C Pasare Journal of leukocyte biology 94 (3), 409-421, 2013 | 102 | 2013 |
Expression of Foxp3 by T follicular helper cells in end-stage germinal centers JT Jacobsen, W Hu, TB R. Castro, S Solem, A Galante, Z Lin, SJ Allon, ... Science 373 (6552), eabe5146, 2021 | 81 | 2021 |
Differential outcome of TRIF-mediated signaling in TLR4 and TLR3 induced DC maturation W Hu, A Jain, Y Gao, IM Dozmorov, R Mandraju, EK Wakeland, C Pasare Proceedings of the National Academy of Sciences 112 (45), 13994-13999, 2015 | 76 | 2015 |
The transcription factor Foxp3 shapes regulatory T cell identity by tuning the activity of trans-acting intermediaries J van der Veeken, A Glasner, Y Zhong, W Hu, ZM Wang, R Bou-Puerto, ... Immunity 53 (5), 971-984. e5, 2020 | 75 | 2020 |
Genetic tracing reveals transcription factor Foxp3-dependent and Foxp3-independent functionality of peripherally induced Treg cells J van der Veeken, C Campbell, Y Pritykin, M Schizas, J Verter, W Hu, ... Immunity 55 (7), 1173-1184. e7, 2022 | 49 | 2022 |
Regulatory T cells function in established systemic inflammation and reverse fatal autoimmunity W Hu, ZM Wang, Y Feng, M Schizas, BE Hoyos, J van der Veeken, ... Nature immunology 22 (9), 1163-1174, 2021 | 49 | 2021 |
ARC syndrome-linked Vps33B protein is required for inflammatory endosomal maturation and signal termination MA Akbar, R Mandraju, C Tracy, W Hu, C Pasare, H Krämer Immunity 45 (2), 267-279, 2016 | 38 | 2016 |
The solution structure of Escherichia coli Wzb reveals a novel substrate recognition mechanism of prokaryotic low molecular weight protein-tyrosine phosphatases E Lescop, Y Hu, H Xu, W Hu, J Chen, B Xia, C Jin Journal of Biological Chemistry 281 (28), 19570-19577, 2006 | 37 | 2006 |
Solution Structure and Backbone Dynamics of an Endopeptidase HycI from scherichia coli: IMPLICATIONS FOR MECHANISM OF THE [NiFe] HYDROGENASE MATURATION F Yang, W Hu, H Xu, C Li, B Xia, C Jin Journal of Biological Chemistry 282 (6), 3856-3863, 2007 | 23 | 2007 |
Distinct metabolic requirements regulate B cell activation and germinal center responses R Sharma, RM Smolkin, P Chowdhury, KC Fernandez, Y Kim, M Cols, ... Nature Immunology 24 (8), 1358-1369, 2023 | 19 | 2023 |
Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies A Glasner, SA Rose, R Sharma, H Gudjonson, T Chu, JA Green, ... Nature immunology 24 (6), 1020-1035, 2023 | 15 | 2023 |
Enhancement of anti-tumor CD8 immunity by IgG1-mediated targeting of Fc receptors SN Furlan, R Mandraju, T Brewer, K Roybal, TD Troutman, W Hu, ... MAbs 6 (1), 108-118, 2014 | 6 | 2014 |