The role of phage display in therapeutic antibody discovery CEZ Chan, APC Lim, PA MacAry, BJ Hanson International immunology 26 (12), 649-657, 2014 | 123 | 2014 |
The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal … CEZ Chan, SGK Seah, DH Chye, S Massey, M Torres, APC Lim, ... PLoS One 16 (6), e0253487, 2021 | 92 | 2021 |
The use of antibodies in the treatment of infectious diseases CE Chan, AHY Chan, BJ Hanson, EE Ooi Singapore Med J 50 (7), 663-672, 2009 | 78 | 2009 |
Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia D Asarnow, B Wang, WH Lee, Y Hu, CW Huang, B Faust, PML Ng, ... Cell 184 (12), 3192-3204. e16, 2021 | 67 | 2021 |
Neutralizing human monoclonal antibody against H5N1 influenza HA selected from a Fab-phage display library APC Lim, CEZ Chan, SKK Wong, AHY Chan, EE Ooi, BJ Hanson Virology journal 5, 1-10, 2008 | 63 | 2008 |
Comparison of the efficiency of antibody selection from semi-synthetic scFv and non-immune Fab phage display libraries against protein targets for rapid development of … CEZ Chan, AHY Chan, APC Lim, BJ Hanson Journal of immunological methods 373 (1-2), 79-88, 2011 | 58 | 2011 |
Enhancing vaccine antibody responses by targeting Clec9A on dendritic cells HY Park, PS Tan, R Kavishna, A Ker, J Lu, CEZ Chan, BJ Hanson, ... NPJ vaccines 2 (1), 31, 2017 | 48 | 2017 |
Optimized expression of full-length IgG1 antibody in a common E. coli strain CEZ Chan, APC Lim, AHY Chan, PA MacAry, BJ Hanson PLoS One 5 (4), e10261, 2010 | 36 | 2010 |
Label-free electronic detection of bio-toxins using aligned carbon nanotubes A Palaniappan, WH Goh, DWH Fam, G Rajaseger, CEZ Chan, BJ Hanson, ... Biosensors and Bioelectronics 43, 143-147, 2013 | 34 | 2013 |
The diagnostic targeting of a carbohydrate virulence factor from M.Tuberculosis CE Chan, S Götze, GT Seah, PH Seeberger, N Tukvadze, MR Wenk, ... Scientific reports 5 (1), 10281, 2015 | 33 | 2015 |
Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A* 11: 01 Y Gu, YH Wong, CW Liew, CEZ Chan, TM Murali, J Yap, CT Too, ... Nature communications 10 (1), 893, 2019 | 32 | 2019 |
IDentif. AI: Rapidly optimizing combination therapy design against severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐Cov‐2) with digital drug development A Blasiak, JJ Lim, SGK Seah, T Kee, A Remus, DH Chye, PS Wong, ... Bioengineering & translational medicine 6 (1), e10196, 2021 | 30 | 2021 |
Novel phage display-derived mycolic acid-specific antibodies with potential for tuberculosis diagnosis [S] CE Chan, BZ Zhao, A Cazenave-Gassiot, SW Pang, AK Bendt, MR Wenk, ... Journal of lipid research 54 (10), 2924-2932, 2013 | 28 | 2013 |
Epitope characterization of the protective monoclonal antibody VN04-2 shows broadly neutralizing activity against highly pathogenic H5N1 APC Lim, SKK Wong, AHY Chan, CEZ Chan, EE Ooi, BJ Hanson Virology Journal 5, 1-4, 2008 | 23 | 2008 |
The IDentif. AI-x pandemic readiness platform: Rapid prioritization of optimized COVID-19 combination therapy regimens A Blasiak, ATL Truong, A Remus, L Hooi, SGK Seah, P Wang, DH Chye, ... NPJ Digital Medicine 5 (1), 83, 2022 | 22 | 2022 |
TCR–like antibodies mediate complement and antibody-dependent cellular cytotoxicity against Epstein-Barr virus–transformed B lymphoblastoid cells expressing different HLA-A* 02 … J Lai, JAL Choo, WJ Tan, CT Too, MZ Oo, MA Suter, FB Mustafa, ... Scientific Reports 7 (1), 9923, 2017 | 16 | 2017 |
The molecular engineering of an anti-idiotypic antibody for pharmacokinetic analysis of a fully human anti-infective SY Lim, CEZ Chan, MM Lisowska, BJ Hanson, PA MacAry PLoS One 10 (12), e0145381, 2015 | 13 | 2015 |
Generation and characterization of a novel recombinant antibody against 15-ketocholestane isolated by phage-display MO Islam, YT Lim, CEZ Chan, A Cazenave-Gassiot, JL Croxford, ... International Journal of Molecular Sciences 13 (4), 4937-4948, 2012 | 11 | 2012 |
Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins PA Macary, CEZ Chan, BJ Hanson, MR Wenk US Patent 9,315,566, 2016 | 9 | 2016 |
Defining the specificity and function of a human neutralizing antibody for Hepatitis B virus S Jhajharia, F Lai, HB Low, K Purushotorman, BDO Shunmuganathan, ... npj Vaccines 7 (1), 121, 2022 | 7 | 2022 |