In-silico drug trials for precision medicine in atrial fibrillation: From ionic mechanisms to electrocardiogram-based predictions in structurally-healthy human atria A Dasi, A Roy, R Sachetto, J Camps, A Bueno-Orovio, B Rodriguez Frontiers in physiology 13, 966046, 2022 | 17 | 2022 |
What determines the optimal pharmacological treatment of atrial fibrillation? Insights from in silico trials in 800 virtual atria A Dasí, MTB Pope, RS Wijesurendra, TR Betts, R Sachetto, ... The Journal of Physiology 601 (18), 4013-4032, 2023 | 5 | 2023 |
Electrocardiogram metrics identify ionic current dysregulation relevant to atrial fibrillation A Dasi, A Roy, A Bueno-Orovio, B Rodriguez European Heart Journal 43 (Supplement_2), ehac544. 572, 2022 | 4 | 2022 |
In Silico TRials guide optimal stratification of ATrIal FIbrillation patients to Catheter Ablation and pharmacological medicaTION: the i-STRATIFICATION study A Dasí, C Nagel, MTB Pope, RS Wijesurendra, TR Betts, R Sachetto, ... EP Europace 26 (6), 2024 | 3 | 2024 |
Analysis of the response of human iPSC-derived cardiomyocyte tissue to ICaL block. A combined in vitro and in silico approach A Dasí, I Hernández-Romero, JF Gomez, AM Climent, JM Ferrero, ... Computers in biology and medicine 137, 104796, 2021 | 2 | 2021 |
Impact of effective refractory period personalization on prediction of atrial fibrillation vulnerability P Martinez Diaz, C Goetz, A Dasi, LA Unger, A Haas, O Doessel, A Luik, ... Europace 25 (Supplement_1), euad122. 542, 2023 | 1 | 2023 |
Combined SK and K2P channel block cardioverts atrial fibrillation in 82% of cases, doubling the efficacy of single channel block A Dasi, A Bueno-Orovio, B Rodriguez European Heart Journal 45 (Supplement_1), ehae666. 526, 2024 | | 2024 |
Impact of effective refractory period personalization on arrhythmia vulnerability in patient-specific atrial computer models P Martínez Díaz, A Dasí, C Goetz, LA Unger, A Haas, A Luik, B Rodríguez, ... Europace 26 (10), euae215, 2024 | | 2024 |
Impact of Effective Refractory Period Personalization on Arrhythmia Vulnerability in Patient-Specific Atrial Computer Models A Dasí, C Goetz, L Unger, A Haas, A Luik, B Rodríguez, O Dössel, ... | | 2024 |
Polypharmacological Modulation of Atrial Fibrillation: Rational Design, Synthesis, and Evaluation of Novel Compounds Targeting NaV1. 5, KV1. 5, and K2P Channels L Camargo-Ayala, M Bedoya, A Dasí, M Prüser, L Prent-Peñaloza, ... | | 2024 |
Early atrial remodelling drives arrhythmia in Fabry Disease A Roy, C O'Shea, A Dasi, L Patel, M Cumberland, D Nieves, ... bioRxiv, 2024.08. 13.607853, 2024 | | 2024 |
Towards prospective in-silico trials in atrial fibrillation: the case of polypharmacological SK and K2P channel block A Dasi, LA Berg, H Martinez-Navarro, A Bueno-Orovio, B Rodriguez bioRxiv, 2024.03. 30.586087, 2024 | | 2024 |
The novel left atrial anterior'seatbelt'line reduces sustained atrial arrhythmia by 72% compared to pulmonary vein isolation alone in a cohort of 400 virtual atria models A Dasi, C Nagel, R Wijesurendra, TR Betts, A Loewe, A Bueno-Orovio, ... Europace 25 (Supplement_1), euad122. 156, 2023 | | 2023 |
OPEN ACCESS EDITED BY O Berenfeld, EA Sobie, WR Giles, B Rodriguez, A Dasí, A Dasí¹, A Roy¹, ... Atrial fibrillation: Technologies for investigation, monitoring and …, 2023 | | 2023 |
Electrocardiogram Analysis Reveals Ionic Current Dysregulation Relevant for Atrial Fibrillation A Dasí, C Nagel, A Loewe, J Camps, A Bueno-Orovio, B Rodriguez 2022 Computing in Cardiology (CinC) 498, 1-4, 2022 | | 2022 |
Reduced Myofilament Contraction in Human Heart Failure. Insights From Electromechanical Simulations MT Mora, S Gutiérrez, A Dasí, JF Gomez, B Trenor 2020 Computing in Cardiology, 1-4, 2020 | | 2020 |
Blocking L-Type Calcium Current Reduces Vulnerability to Re-Entry in Human iPSC-Derived Cardiomyocytes Tissue A Dasi, AM Climent, L Martinez, JF Gomez, JM Ferrero, B Trenor 2019 Computing in Cardiology (CinC), Page 1-Page 4, 2019 | | 2019 |
Fibroblasts Induce Calcium Alternans When Coupled to Cardiomyocytes: A Simulation Study MT Mora, A Dasi, J Saiz, B Trenor, JM Ferrero 2018 Computing in Cardiology Conference (CinC) 45, 1-4, 2018 | | 2018 |