Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry GA Snyder, D Deredge, A Waldhuber, T Fresquez, DZ Wilkins, PT Smith, ... Journal of Biological Chemistry 289 (2), 669-679, 2014 | 90 | 2014 |
Conformational dynamics of a neurotransmitter: sodium symporter in a lipid bilayer S Adhikary, DJ Deredge, A Nagarajan, LR Forrest, PL Wintrode, SK Singh Proceedings of the National Academy of Sciences 114 (10), E1786-E1795, 2017 | 84 | 2017 |
Current trends and limitations in dengue antiviral research JO Obi, H Gutiérrez-Barbosa, JV Chua, DJ Deredge Tropical Medicine and Infectious Disease 6 (4), 180, 2021 | 71 | 2021 |
IL-1 family cytokines use distinct molecular mechanisms to signal through their shared co-receptor S Günther, D Deredge, AL Bowers, A Luchini, DA Bonsor, R Beadenkopf, ... Immunity 47 (3), 510-523. e4, 2017 | 68 | 2017 |
The Helicobacter pylori adhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA DA Bonsor, Q Zhao, B Schmidinger, E Weiss, J Wang, D Deredge, ... The EMBO journal 37 (13), e98664, 2018 | 61 | 2018 |
A dimer interface mutation in glyceraldehyde-3-phosphate dehydrogenase regulates its binding to AU-rich RNA MR White, MM Khan, D Deredge, CR Ross, R Quintyn, BE Zucconi, ... Journal of Biological Chemistry 290 (3), 1770-1785, 2015 | 59 | 2015 |
Evolution of structural biology through the lens of mass spectrometry U Kaur, DT Johnson, EE Chea, DJ Deredge, JA Espino, LM Jones Analytical chemistry 91 (1), 142-155, 2018 | 57 | 2018 |
Interlaboratory comparison of hydrogen–deuterium exchange mass spectrometry measurements of the Fab fragment of NISTmAb JW Hudgens, ES Gallagher, I Karageorgos, KW Anderson, JJ Filliben, ... Analytical chemistry 91 (11), 7336-7345, 2019 | 53 | 2019 |
Common coding variant in SERPINA1 increases the risk for large artery stroke R Malik, T Dau, M Gonik, A Sivakumar, DJ Deredge, EV Edeleva, ... Proceedings of the National Academy of Sciences 114 (14), 3613-3618, 2017 | 51 | 2017 |
Bacterial flagellar capping proteins adopt diverse oligomeric states S Postel, D Deredge, DA Bonsor, X Yu, K Diederichs, S Helmsing, ... Elife 5, e18857, 2016 | 50 | 2016 |
Gallium(III)–Salophen as a Dual Inhibitor of Pseudomonas aeruginosa Heme Sensing and Iron Acquisition G Centola, DJ Deredge, K Hom, Y Ai, AT Dent, F Xue, A Wilks ACS infectious diseases 6 (8), 2073-2085, 2020 | 45 | 2020 |
Structure and dynamics of FosA-mediated fosfomycin resistance in Klebsiella pneumoniae and Escherichia coli EH Klontz, AD Tomich, S Günther, JA Lemkul, D Deredge, Z Silverstein, ... Antimicrobial agents and chemotherapy 61 (11), 10.1128/aac. 01572-17, 2017 | 43 | 2017 |
The glutamate effect on DNA binding by pol I DNA polymerases: osmotic stress and the effective reversal of salt linkage DJ Deredge, JT Baker, K Datta, VJ LiCata Journal of molecular biology 401 (2), 223-238, 2010 | 36 | 2010 |
Molecular Basis of Broad Spectrum N-Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2 EH Klontz, B Trastoy, D Deredge, JK Fields, C Li, J Orwenyo, A Marina, ... ACS Central Science 5 (3), 524-538, 2019 | 33 | 2019 |
Structure and dynamics of an α-fucosidase reveal a mechanism for highly efficient IgG transfucosylation EH Klontz, C Li, K Kihn, JK Fields, D Beckett, GA Snyder, PL Wintrode, ... Nature Communications 11 (1), 6204, 2020 | 32 | 2020 |
Antigen-induced allosteric changes in a human IgG1 Fc increase low-affinity Fcγ receptor binding C Orlandi, D Deredge, K Ray, N Gohain, W Tolbert, AL DeVico, ... Structure 28 (5), 516-527. e5, 2020 | 31 | 2020 |
Ligand-induced allostery in the interaction of the Pseudomonas aeruginosa heme binding protein with heme oxygenase DJ Deredge, W Huang, C Hui, H Matsumura, Z Yue, P Moënne-Loccoz, ... Proceedings of the National Academy of Sciences 114 (13), 3421-3426, 2017 | 27 | 2017 |
Hydrogen/deuterium exchange kinetics demonstrate long range allosteric effects of thumb site 2 inhibitors of hepatitis C viral RNA-dependent RNA polymerase D Deredge, J Li, KA Johnson, PL Wintrode Journal of Biological Chemistry 291 (19), 10078-10088, 2016 | 26 | 2016 |
Small-molecule inhibitor of FosA expands fosfomycin activity to multidrug-resistant Gram-negative pathogens AD Tomich, EH Klontz, D Deredge, JP Barnard, CL McElheny, ... Antimicrobial agents and chemotherapy 63 (3), 10.1128/aac. 01524-18, 2019 | 19 | 2019 |
Thumb site 2 inhibitors of hepatitis C viral RNA-dependent RNA polymerase allosterically block the transition from initiation to elongation J Li, D Deredge, PL Wintrode, KA Johnson Biophysical Journal 110 (3), 202a, 2016 | 19 | 2016 |