| The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells H Borges da Silva, LK Beura, H Wang, EA Hanse, R Gore, MC Scott, ... Nature 559 (7713), 264-268, 2018 | 249 | 2018 |
| EGLN1 inhibition and rerouting of α-ketoglutarate suffice for remote ischemic protection BA Olenchock, J Moslehi, AH Baik, SM Davidson, J Williams, WJ Gibson, ... Cell 164 (5), 884-895, 2016 | 158 | 2016 |
| α-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer TQ Tran, EA Hanse, AN Habowski, H Li, MB Ishak Gabra, Y Yang, ... Nature cancer 1 (3), 345-358, 2020 | 116 | 2020 |
| MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1 Y Yang, MB Ishak Gabra, EA Hanse, XH Lowman, TQ Tran, H Li, ... Nature communications 10 (1), 809, 2019 | 116 | 2019 |
| Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer EA Hanse, C Ruan, M Kachman, D Wang, XH Lowman, A Kelekar Oncogene 36 (27), 3915-3924, 2017 | 112 | 2017 |
| p53 promotes cancer cell adaptation to glutamine deprivation by upregulating Slc7a3 to increase arginine uptake XH Lowman, EA Hanse, Y Yang, MBI Gabra, TQ Tran, H Li, M Kong Cell reports 26 (11), 3051-3060. e4, 2019 | 100 | 2019 |
| Distinct proliferative and transcriptional effects of the D-type cyclins in vivo LK Mullany, P White, EA Hanse, CJ Nelsen, MM Goggin, JE Mullany, ... Cell Cycle 7 (14), 2215-2224, 2008 | 100 | 2008 |
| Genomewide microRNA down‐regulation as a negative feedback mechanism in the early phases of liver regeneration J Shu, BT Kren, Z Xia, PYP Wong, L Li, EA Hanse, MX Min, B Li, ... Hepatology 54 (2), 609-619, 2011 | 97 | 2011 |
| Digital transcriptome analysis indicates adaptive mechanisms in the heart of a hibernating mammal KM Brauch, ND Dhruv, EA Hanse, MT Andrews Physiological genomics 23 (2), 227-234, 2005 | 97 | 2005 |
| Cyclin D1 inhibits hepatic lipogenesis via repression of carbohydrate response element binding protein and hepatocyte nuclear factor 4α EA Hanse, DG Mashek, JR Becker, AD Solmonson, LK Mullany, ... Cell cycle 11 (14), 2681-2690, 2012 | 82 | 2012 |
| Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth MB Ishak Gabra, Y Yang, H Li, P Senapati, EA Hanse, XH Lowman, ... Nature communications 11 (1), 3326, 2020 | 77 | 2020 |
| Akt-mediated liver growth promotes induction of cyclin E through a novel translational mechanism and a p21-mediated cell cycle arrest LK Mullany, CJ Nelsen, EA Hanse, MM Goggin, CK Anttila, M Peterson, ... Journal of Biological Chemistry 282 (29), 21244-21252, 2007 | 70 | 2007 |
| Cdk2 plays a critical role in hepatocyte cell cycle progression and survival in the setting of cyclin D1 expression in vivo EA Hanse, CJ Nelsen, MM Goggin, CK Anttila, LK Mullany, C Berthet, ... Cell Cycle 8 (17), 2802-2809, 2009 | 55 | 2009 |
| Heme binding biguanides target cytochrome P450-dependent cancer cell mitochondria Z Guo, IF Sevrioukova, IG Denisov, X Zhang, TL Chiu, DG Thomas, ... Cell chemical biology 24 (10), 1259-1275. e6, 2017 | 52 | 2017 |
| Transcription factor C/EBP-β induces tumor-suppressor phosphatase PHLPP2 through repression of the miR-17–92 cluster in differentiating AML cells Y Yan, EA Hanse, K Stedman, JM Benson, XH Lowman, S Subramanian, ... Cell Death & Differentiation 23 (7), 1232-1242, 2016 | 39 | 2016 |
| Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration I Nakamura, MG Fernandez-Barrena, MC Ortiz-Ruiz, LL Almada, C Hu, ... Journal of Biological Chemistry 288 (29), 21389-21398, 2013 | 39 | 2013 |
| Co-deleting Pten with Rb in retinal progenitor cells in mice results in fully penetrant bilateral retinoblastomas C Xie, H Lu, A Nomura, EA Hanse, CL Forster, JB Parker, MA Linden, ... Molecular cancer 14, 1-11, 2015 | 37 | 2015 |
| In vitro induction of human regulatory T cells using conditions of low tryptophan plus kynurenines KL Hippen, RS O’Connor, AM Lemire, A Saha, EA Hanse, NC Tennis, ... American Journal of Transplantation 17 (12), 3098-3113, 2017 | 36 | 2017 |
| Cyclin D1 represses peroxisome proliferator-activated receptor alpha and inhibits fatty acid oxidation S Kamarajugadda, JR Becker, EA Hanse, DG Mashek, MT Mashek, ... Oncotarget 7 (30), 47674, 2016 | 31 | 2016 |
| Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation CB Karim, L Michel Espinoza-Fonseca, ZM James, EA Hanse, JS Gaynes, ... Scientific reports 5 (1), 14557, 2015 | 24 | 2015 |
