Single-molecule spectroscopy of protein conformational dynamics in live eukaryotic cells I König, A Zarrine-Afsar, M Aznauryan, A Soranno, B Wunderlich, ... nAture methods 12 (8), 773-779, 2015 | 262 | 2015 |
Machine learning for biologics: opportunities for protein engineering, developability, and formulation H Narayanan, F Dingfelder, A Butté, N Lorenzen, M Sokolov, P Arosio Trends in pharmacological sciences 42 (3), 151-165, 2021 | 112 | 2021 |
Integrated view of internal friction in unfolded proteins from single-molecule FRET, contact quenching, theory, and simulations A Soranno, A Holla, F Dingfelder, D Nettels, DE Makarov, B Schuler Biophysical Journal 112 (3), 318a, 2017 | 108 | 2017 |
Design of biopharmaceutical formulations accelerated by machine learning H Narayanan, F Dingfelder, I Condado Morales, B Patel, KE Heding, ... Molecular Pharmaceutics 18 (10), 3843-3853, 2021 | 38 | 2021 |
Rapid microfluidic dilution for single‐molecule spectroscopy of low‐affinity biomolecular complexes N Zijlstra, F Dingfelder, B Wunderlich, F Zosel, S Benke, D Nettels, ... Angewandte Chemie International Edition 56 (25), 7126-7129, 2017 | 22 | 2017 |
Mapping an equilibrium folding intermediate of the cytolytic pore toxin ClyA with single-molecule FRET F Dingfelder, S Benke, D Nettels, B Schuler The Journal of Physical Chemistry B 122 (49), 11251-11261, 2018 | 20 | 2018 |
Rapid microfluidic double-jump mixing device for single-molecule spectroscopy F Dingfelder, B Wunderlich, S Benke, F Zosel, N Zijlstra, D Nettels, ... Journal of the American Chemical Society 139 (17), 6062-6065, 2017 | 19 | 2017 |
Slow escape from a helical misfolded state of the pore-forming toxin cytolysin A F Dingfelder, I Macocco, S Benke, D Nettels, P Faccioli, B Schuler JACS Au 1 (8), 1217-1230, 2021 | 9 | 2021 |
Measuring self-association of antibody lead candidates with dynamic light scattering F Dingfelder, A Henriksen, PO Wahlund, P Arosio, N Lorenzen Therapeutic Antibodies: Methods and Protocols, 241-258, 2022 | 6 | 2022 |
Microfluidic Stress Device to Decouple the Synergistic Effect of Shear and Interfaces on Antibody Aggregation MS Gerlt, EM Meier, F Dingfelder, D Zürcher, M Müller, P Arosio Journal of Pharmaceutical Sciences, 2024 | | 2024 |
Microfluidic Devices for Probing Protein Dynamics with Single-Molecule Spectroscopy F Dingfelder University of Zurich, 2018 | | 2018 |
RDC-basierte Strukturverfeinerung von NfeD-ß-Barrel-Domänen F Dingfelder | | 2011 |
Graduate School of Chemical and Molecular Sciences Zurich R Alberto, S Bienz, L Bigler, EC Böttger, H Braband, D Brühwiler, ... | | |