Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism Y Zhao, H Liu, Z Liu, Y Ding, SP LeDoux, GL Wilson, R Voellmy, Y Lin, ... Cancer research 71 (13), 4585-4597, 2011 | 306 | 2011 |
Endoplasmic reticulum stress in disorders of myelinating cells W Lin, B Popko Nature neuroscience 12 (4), 379-385, 2009 | 271 | 2009 |
Interferon-γ inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress W Lin, A Kemper, JL Dupree, HP Harding, D Ron, B Popko Brain 129 (5), 1306-1318, 2006 | 246 | 2006 |
Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-γ W Lin, HP Harding, D Ron, B Popko The Journal of cell biology 169 (4), 603-612, 2005 | 229 | 2005 |
The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage W Lin, SL Bailey, H Ho, HP Harding, D Ron, SD Miller, B Popko The Journal of clinical investigation 117 (2), 448-456, 2007 | 222 | 2007 |
Interferon-γ induced medulloblastoma in the developing cerebellum W Lin, A Kemper, KD McCarthy, P Pytel, JP Wang, IL Campbell, MF Utset, ... Journal of Neuroscience 24 (45), 10074-10083, 2004 | 129 | 2004 |
Immunoregulatory protein B7-H3 reprograms glucose metabolism in cancer cells by ROS-mediated stabilization of HIF1α S Lim, H Liu, LM Da Silva, R Arora, Z Liu, JB Phillips, DC Schmitt, T Vu, ... Cancer research 76 (8), 2231-2242, 2016 | 128 | 2016 |
Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis W Lin, Y Lin, J Li, AG Fenstermaker, SW Way, B Clayton, S Jamison, ... Journal of Neuroscience 33 (14), 5980-5991, 2013 | 122 | 2013 |
Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-γ W Lin, PE Kunkler, HP Harding, D Ron, RP Kraig, B Popko The American journal of pathology 173 (5), 1508-1517, 2008 | 107 | 2008 |
The unfolded protein response in multiple sclerosis S Stone, W Lin Frontiers in neuroscience 9, 264, 2015 | 101 | 2015 |
ZFP191 is required by oligodendrocytes for CNS myelination SYB Howng, RL Avila, B Emery, M Traka, W Lin, T Watkins, S Cook, ... Genes & development 24 (3), 301-311, 2010 | 97 | 2010 |
Inducible production of interferon-γ in the developing brain causes cerebellar dysplasia with activation of the Sonic hedgehog pathway J Wang, W Lin, B Popko, IL Campbell Molecular and Cellular Neuroscience 27 (4), 489-496, 2004 | 85 | 2004 |
Sephin1, which prolongs the integrated stress response, is a promising therapeutic for multiple sclerosis Y Chen, JR Podojil, RB Kunjamma, J Jones, M Weiner, W Lin, SD Miller, ... Brain 142 (2), 344-361, 2019 | 74 | 2019 |
Role of nuclear factor κB in multiple sclerosis and experimental autoimmune encephalomyelitis Y Yue, S Stone, W Lin Neural regeneration research 13 (9), 1507-1515, 2018 | 73 | 2018 |
Interferon-γ activates nuclear factor-κ B in oligodendrocytes through a process mediated by the unfolded protein response Y Lin, S Jamison, W Lin PloS one 7 (5), e36408, 2012 | 60 | 2012 |
NF-κB activation protects oligodendrocytes against inflammation S Stone, S Jamison, Y Yue, W Durose, R Schmidt-Ullrich, W Lin Journal of Neuroscience 37 (38), 9332-9344, 2017 | 56 | 2017 |
Regulation of PERK–eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes M Jiang, L Liu, X He, H Wang, W Lin, H Wang, SO Yoon, TL Wood, QR Lu Nature communications 7 (1), 12185, 2016 | 56 | 2016 |
Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice Y Lin, X Pang, G Huang, S Jamison, J Fang, HP Harding, D Ron, W Lin Journal of Neuroscience 34 (36), 12182-12191, 2014 | 56 | 2014 |
PERK activation preserves the viability and function of remyelinating oligodendrocytes in immune-mediated demyelinating diseases Y Lin, G Huang, S Jamison, J Li, HP Harding, D Ron, W Lin The American journal of pathology 184 (2), 507-519, 2014 | 49 | 2014 |
Interferon‐γ inhibits central nervous system myelination through both STAT1‐dependent and STAT1‐independent pathways W Lin, Y Lin Journal of neuroscience research 88 (12), 2569-2577, 2010 | 48 | 2010 |