| Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development K Giannikou, IA Malinowska, TJ Pugh, R Yan, YY Tseng, C Oh, J Kim, ... PLoS genetics 12 (8), e1006242, 2016 | 118 | 2016 |
| TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism N Alesi, EW Akl, D Khabibullin, HJ Liu, AS Nidhiry, ER Garner, ... Nature communications 12 (1), 4245, 2021 | 75 | 2021 |
| TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti–PD-1/anti–CTLA-4 immunotherapy HJ Liu, PH Lizotte, H Du, MC Speranza, HC Lam, S Vaughan, N Alesi, ... JCI insight 3 (8), 2018 | 63 | 2018 |
| p62/SQSTM1 cooperates with hyperactive mTORC1 to regulate glutathione production, maintain mitochondrial integrity, and promote tumorigenesis HC Lam, CV Baglini, AL Lope, AA Parkhitko, HJ Liu, N Alesi, ... Cancer research 77 (12), 3255-3267, 2017 | 59 | 2017 |
| Clinical pharmacogenetics of methotrexate P Castaldo, S Magi, A Assunta Nasti, S Arcangeli, V Lariccia, N Alesi, ... Current drug metabolism 12 (3), 278-286, 2011 | 32 | 2011 |
| Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells HC Lam, HJ Liu, CV Baglini, H Filippakis, N Alesi, J Nijmeh, H Du, ... Oncotarget 8 (39), 64714, 2017 | 25 | 2017 |
| TFEB drives mTORC1 hyperactivation and kidney disease in Tuberous Sclerosis Complex N Alesi, D Khabibullin, DM Rosenthal, EW Akl, PM Cory, M Alchoueiry, ... Nature Communications 15 (1), 406, 2024 | 17 | 2024 |
| Lysosomal regulation of cholesterol homeostasis in tuberous sclerosis complex is mediated via NPC1 and LDL-R H Filippakis, N Alesi, B Ogorek, J Nijmeh, D Khabibullin, C Gutierrez, ... Oncotarget 8 (24), 38099, 2017 | 16 | 2017 |
| Vps34-mediated macropinocytosis in Tuberous Sclerosis Complex 2-deficient cells supports tumorigenesis H Filippakis, A Belaid, B Siroky, C Wu, N Alesi, T Hougard, J Nijmeh, ... Scientific reports 8 (1), 14161, 2018 | 15 | 2018 |
| Basic aspects of osteoclast differentiation and function N Alesi, JF Charles, MC Nakamura Osteoporosis: Pathophysiology and Clinical Management, 17-41, 2020 | 9 | 2020 |
| Keeping up with the Rag GTPases N Alesi, EP Henske Nature Cell Biology 24 (9), 1330-1331, 2022 | 6 | 2022 |
| The Spectrum of Renal “TFEopathies”: Flipping the mTOR Switch in Renal Tumorigenesis N Alesi, K Asrani, TL Lotan, EP Henske Physiology 39 (6), 347-359, 2024 | | 2024 |
| Low Serum Progranulin Levels as a Biomarker in the First Reported Case of Progranulin (GRN) Variant Associated Fibrotic Lung and Liver Disease JC Kennedy, S Vargas, MP Fishman, C Garcia De Alba Rivas, SH Baek, ... C60. CHILDHOOD INTERSTITIAL LUNG DISEASE (chILD), A5481-A5481, 2023 | | 2023 |
| Integration of Clinical Exome Sequencing with In-Situ RNA Expression Profiling< strike> t o Diagnosis and Guide Therapy of a New Cause of Rapidly Progressive Fibrotic Childhood … JC Kennedy, SO Vargas, MP Fishman, N Alesi, N Carmichael, AR Bolivar, ... AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 205, 2022 | | 2022 |
Integration of Clinical Exome Sequencing with In-Situ RNA Expression Profiling to Diagnosis and Guide Therapy of a New Cause of Rapidly Progressive Fibrotic …JC Kennedy, SO Vargas, MP Fishman, N Alesi, N Carmichael, ... A15. A BEAUTIFUL MIND: BIG DATA APPROACHES TO PEDIATRIC LUNG DISEASE, A1018 …, 2022 | | 2022 |
| Identification of Loss-of-Function Granulin Mutation as a New Cause of Childhood Interstitial Lung Disease Responsive to Anti-TNF-Alpha Biologics JC Kennedy, N Alesi, S Vargas, MP Fishman, EW Akl, D Khabibullin, ... TP70. TP070 DIFFUSE LUNG DISEASE AND RARE DISEASE, A3268-A3268, 2021 | | 2021 |
| Correction: p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis HC Lam, CV Baglini, AL Lope, AA Parkhitko, HJ Liu, N Alesi, ... Cancer Research 80 (23), 5424-5424, 2020 | | 2020 |
| Abstract A01: Vps34 promotes macropinocytosis in Tsc2-deficient cells C Filippakis, A Belaid, B Siroky, C Wu, N Alesi, T Alesi, J Nijmeh, HC Lam, ... Molecular Cancer Research 18 (10_Supplement), A01-A01, 2020 | | 2020 |
| Vps34 promotes macropinocytosis in Tsc2-deficient cells. C Filippakis, A Belaid, B Siroky, C Wu, N Alesi, T Alesi, J Nijmeh, HC Lam, ... MOLECULAR CANCER RESEARCH 18 (10), 30-30, 2020 | | 2020 |
| Osteoclast-specific Tsc2 deletion in mice increases bone mass: a model for the study of sclerotic bone lesions in Tuberous Sclerosis N Alesi Università Politecnica delle Marche, 2017 | | 2017 |
