Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 647 | 2020 |
Structure of the toxic core of α-synuclein from invisible crystals JA Rodriguez, MI Ivanova, MR Sawaya, D Cascio, FE Reyes, D Shi, ... Nature 525 (7570), 486-490, 2015 | 632 | 2015 |
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... Science 370 (6523), 1473-1479, 2020 | 386 | 2020 |
Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS) S Sangwan, A Zhao, KL Adams, CK Jayson, MR Sawaya, EL Guenther, ... Proceedings of the National Academy of Sciences 114 (33), 8770-8775, 2017 | 118 | 2017 |
Crystal structures of IAPP amyloidogenic segments reveal a novel packing motif of out-of-register beta sheets AB Soriaga, S Sangwan, R Macdonald, MR Sawaya, D Eisenberg The Journal of Physical Chemistry B 120 (26), 5810-5816, 2016 | 72 | 2016 |
An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... BioRxiv, 2020 | 66 | 2020 |
Inhibition of synucleinopathic seeding by rationally designed inhibitors S Sangwan, S Sahay, KA Murray, S Morgan, EL Guenther, L Jiang, ... Elife 9, e46775, 2020 | 60 | 2020 |
Perspective on SOD1 mediated toxicity in Amyotrophic Lateral Sclerosis S Sangwan, DS Eisenberg Postępy Biochemii 62 (3), 362-369, 2016 | 38 | 2016 |
Factors that drive peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants TD Do, NE LaPointe, S Sangwan, DB Teplow, SC Feinstein, MR Sawaya, ... The Journal of Physical Chemistry B 118 (26), 7247-7256, 2014 | 31 | 2014 |
Atomic structures of corkscrew‐forming segments of SOD1 reveal varied oligomer conformations S Sangwan, MR Sawaya, KA Murray, MP Hughes, DS Eisenberg Protein Science 27 (7), 1231-1242, 2018 | 25 | 2018 |
Distal amyloid β‐protein fragments template amyloid assembly TD Do, S Sangwan, NEC de Almeida, AI Ilitchev, M Giammona, ... Protein Science 27 (7), 1181-1190, 2018 | 12 | 2018 |
Consortium QSB, Walter P, Manglik A M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... Science 370 (6523), 1473, 2020 | 10 | 2020 |
A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response A Subramanian, L Wang, T Moss, M Voorhies, S Sangwan, E Stevenson, ... Nature Cell Biology 25 (11), 1600-1615, 2023 | 6 | 2023 |
A Legionella toxin mimics tRNA and glycosylates the translation machinery to trigger a ribotoxic stress response A Subramanian, L Wang, T Moss, M Voorhies, S Sangwan, E Stevenson, ... bioRxiv, 2022.06. 10.495705, 2022 | 3 | 2022 |
Structure-based peptide inhibitors of alpha-synuclein aggregation DS Eisenberg, S Sangwan, L Jiang US Patent App. 17/848,736, 2023 | 2 | 2023 |
Full wwPDB X-ray Structure Validation Report i Y Kim, KH Kim | 1 | 2023 |
A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling RE Lawrence, SR Shoemaker, A Deal, S Sangwan, AA Anand, L Wang, ... Nature Chemical Biology 20 (4), 422-431, 2024 | | 2024 |
A central helical fulcrum in eIF2B coordinates allosteric regulation of Integrated Stress Response signaling RE Lawrence, S Shoemaker, A Deal, S Sangwan, A Anand, L Wang, ... bioRxiv, 2022.12. 22.521453, 2022 | | 2022 |
Structure-based peptide inhibitors of α-synuclein aggregation DS Eisenberg, S Sangwan, L Jiang US Patent 11,390,646, 2022 | | 2022 |
Structure-based peptide inhibitors of alpha-synuclein aggregation DS Eisenberg, S Sangwan, L Jiang | | 2018 |