Radiotherapy and immunotherapy promote tumoral lipid oxidation and ferroptosis via synergistic repression of SLC7A11 X Lang, MD Green, W Wang, J Yu, JE Choi, L Jiang, P Liao, J Zhou, ... Cancer discovery 9 (12), 1673-1685, 2019 | 712 | 2019 |
Inhibition of ATM increases interferon signaling and sensitizes pancreatic cancer to immune checkpoint blockade therapy Q Zhang, MD Green, X Lang, J Lazarus, JD Parsels, S Wei, LA Parsels, ... Cancer research 79 (15), 3940-3951, 2019 | 180 | 2019 |
The oncogenic role of Yin Yang 1 Q Zhang, DB Stovall, K Inoue, G Sui Critical Reviews™ in Oncogenesis 16 (3-4), 2011 | 163 | 2011 |
FBXW7 facilitates nonhomologous end-joining via K63-linked polyubiquitylation of XRCC4 Q Zhang, D Karnak, M Tan, TS Lawrence, MA Morgan, Y Sun Molecular cell 61 (3), 419-433, 2016 | 121 | 2016 |
Yin Yang 1 contains G-quadruplex structures in its promoter and 5′-UTR and its expression is modulated by G4 resolvase 1 W Huang, PJ Smaldino, Q Zhang, LD Miller, P Cao, K Stadelman, M Wan, ... Nucleic acids research 40 (3), 1033-1049, 2012 | 120 | 2012 |
PARP1 trapping and DNA replication stress enhance radiosensitization with combined WEE1 and PARP inhibitors LA Parsels, D Karnak, JD Parsels, Q Zhang, J Vélez-Padilla, ZR Reichert, ... Molecular Cancer Research 16 (2), 222-232, 2018 | 119 | 2018 |
Ezrin promotes invasion and metastasis of pancreatic cancer cells Y Meng, Z Lu, S Yu, Q Zhang, Y Ma, J Chen Journal of translational medicine 8, 1-14, 2010 | 115 | 2010 |
Sensitization of pancreatic cancer to chemoradiation by the Chk1 inhibitor MK8776 CG Engelke, LA Parsels, Y Qian, Q Zhang, D Karnak, JR Robertson, ... Clinical cancer research 19 (16), 4412-4421, 2013 | 114 | 2013 |
Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27 M Wan, W Huang, TE Kute, LD Miller, Q Zhang, H Hatcher, J Wang, ... The American journal of pathology 180 (5), 2120-2133, 2012 | 108 | 2012 |
LSD1 destabilizes FBXW7 and abrogates FBXW7 functions independent of its demethylase activity H Lan, M Tan, Q Zhang, F Yang, S Wang, H Li, X Xiong, Y Sun Proceedings of the National Academy of Sciences 116 (25), 12311-12320, 2019 | 73 | 2019 |
The regulation of SOX7 and its tumor suppressive role in breast cancer DB Stovall, M Wan, LD Miller, P Cao, D Maglic, Q Zhang, MR Stampfer, ... The American journal of pathology 183 (5), 1645-1653, 2013 | 72 | 2013 |
Myostatin induces p300 degradation to silence cyclin D1 expression through the PI3K/PTEN/Akt pathway M Ji, Q Zhang, J Ye, X Wang, W Yang, D Zhu Cellular signalling 20 (8), 1452-1458, 2008 | 69 | 2008 |
hSGT interacts with the N-terminal region of myostatin H Wang, Q Zhang, D Zhu Biochemical and biophysical research communications 311 (4), 877-883, 2003 | 67 | 2003 |
RNF13: a novel RING-type ubiquitin ligase over-expressed in pancreatic cancer Q Zhang, Y Meng, L Zhang, J Chen, D Zhu Cell research 19 (3), 348-357, 2009 | 66 | 2009 |
The role of YY1 in oncogenesis and its potential as a drug target in cancer therapies J Shi, A Hao, Q Zhang, G Sui Current cancer drug targets 15 (2), 145-157, 2015 | 65 | 2015 |
FBXO40, a gene encoding a novel muscle-specific F-box protein, is upregulated in denervation-related muscle atrophy J Ye, Y Zhang, J Xu, Q Zhang, D Zhu Gene 404 (1-2), 53-60, 2007 | 57 | 2007 |
Targeted Degradation of KRAS by an Engineered Ubiquitin Ligase Suppresses Pancreatic Cancer Cell Growth In Vitro and In Vivo Y Ma, Y Gu, Q Zhang, Y Han, S Yu, Z Lu, J Chen Molecular cancer therapeutics 12 (3), 286-294, 2013 | 54 | 2013 |
Neddylation inhibition upregulates PD‐L1 expression and enhances the efficacy of immune checkpoint blockade in glioblastoma S Zhou, X Zhao, Z Yang, R Yang, C Chen, K Zhao, W Wang, Y Ma, ... International journal of cancer 145 (3), 763-774, 2019 | 44 | 2019 |
Fbxw7 deletion accelerates KrasG12D-Driven pancreatic tumorigenesis via Yap accumulation Q Zhang, Y Zhang, JD Parsels, I Lohse, TS Lawrence, MP di Magliano, ... Neoplasia 18 (11), 666-673, 2016 | 42 | 2016 |
Fatty acid synthase is a primary target of MiR-15a and MiR-16-1 in breast cancer J Wang, X Zhang, J Shi, P Cao, M Wan, Q Zhang, Y Wang, SJ Kridel, ... Oncotarget 7 (48), 78566, 2016 | 40 | 2016 |