Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer H Huang, Z Wang, Y Zhang, RN Pradhan, D Ganguly, R Chandra, ... Cancer Cell 40 (6), 656-673. e7, 2022 | 231 | 2022 |
Targeting TGF βR2‐mutant tumors exposes vulnerabilities to stromal TGF β blockade in pancreatic cancer H Huang, Y Zhang, V Gallegos, N Sorrelle, MM Zaid, J Toombs, W Du, ... EMBO molecular medicine 11 (11), e10515, 2019 | 67 | 2019 |
Improved multiplex immunohistochemistry for immune microenvironment evaluation of mouse formalin-fixed, paraffin-embedded tissues N Sorrelle, D Ganguly, ATA Dominguez, Y Zhang, H Huang, LN Dahal, ... The Journal of Immunology 202 (1), 292-299, 2019 | 49 | 2019 |
Direct and indirect regulation of the tumor immune microenvironment by VEGF Y Zhang, RA Brekken Journal of leukocyte biology 111 (6), 1269-1286, 2022 | 40 | 2022 |
VEGFR2 activity on myeloid cells mediates immune suppression in the tumor microenvironment Y Zhang, H Huang, M Coleman, A Ziemys, P Gopal, SM Kazmi, ... JCI insight 6 (23), 2021 | 26 | 2021 |
The characteristics of naive-like T cells in tumor-infiltrating lymphocytes from human lung cancer SY Sheng, Y Gu, CG Lu, YY Tang, JY Zou, YQ Zhang, RF Wang, H Hong Journal of Immunotherapy 40 (1), 1-10, 2017 | 24 | 2017 |
Perspectives on hypoxia signaling in tumor stroma Y Zhang, M Coleman, RA Brekken Cancers 13 (12), 3070, 2021 | 19 | 2021 |
Cyclooxygenase-2 inhibition potentiates the efficacy of vascular endothelial growth factor blockade and promotes an immune stimulatory microenvironment in preclinical models of … Y Zhang, A Kirane, H Huang, NB Sorrelle, FJ Burrows, MT Dellinger, ... Molecular Cancer Research 17 (2), 348-355, 2019 | 18 | 2019 |
AXL is a key factor for cell plasticity and promotes metastasis in pancreatic cancer W Du, NZ Phinney, H Huang, Z Wang, J Westcott, JE Toombs, Y Zhang, ... Molecular Cancer Research 19 (8), 1412-1421, 2021 | 17 | 2021 |
Effects of glycogen synthase kinase-3β inhibitor TWS119 on proliferation and cytokine production of TILs from human lung cancer YY Tang, SY Sheng, CG Lu, YQ Zhang, JY Zou, YY Lei, Y Gu, H Hong Journal of Immunotherapy 41 (7), 319-328, 2018 | 16 | 2018 |
AXL inhibitor TP-0903 reduces metastasis and therapy resistance in pancreatic cancer Y Zhang, EN Arner, A Rizvi, JE Toombs, H Huang, SL Warner, JM Foulks, ... Molecular cancer therapeutics 21 (1), 38-47, 2022 | 11 | 2022 |
Are TEMs canceled? Questioning the functional relevance of tie2-expressing macrophages Y Zhang, RA Brekken Cancer research 82 (7), 1172-1173, 2022 | 2 | 2022 |
Selective inhibition of VEGF binding to VEGFR2 promotes an immune stimulatory microenvironment in murine models of breast cancer. Y Zhang, H Huang, N Sorrelle, R Brekken CANCER IMMUNOLOGY RESEARCH 9 (2), 2021 | | 2021 |
Abstract PR011: Selective inhibition of VEGF binding to VEGFR2 promotes an immune stimulatory microenvironment in murine models of breast cancer Y Zhang, H Huang, N Sorrelle, R Brekken Cancer Immunology Research 9 (2_Supplement), PR011-PR011, 2021 | | 2021 |
Immune toxicity and flow cytometry of circulating blood cells in cancer patients receiving immune therapy. SA Khan, N Sorrelle, RA Brekken, R Lu, MS von Itzstein, D Xie, D Hsieh, ... Journal of Clinical Oncology 38 (15_suppl), e15126-e15126, 2020 | | 2020 |
Abstract C092: Axl inhibitor TP-0903 augments chemo-and immunotherapy efficacy in pancreatic cancer Y Zhang, EN Arner, JE Toombs, JM Foulks, SL Warner, RA Brekken Molecular Cancer Therapeutics 18 (12_Supplement), C092-C092, 2019 | | 2019 |