Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study L Hou, U Heilbronner, F Degenhardt, M Adli, K Akiyama, N Akula, ... The Lancet 387 (10023), 1085-1093, 2016 | 398 | 2016 |
Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder L Hou, SE Bergen, N Akula, J Song, CM Hultman, M Landén, M Adli, ... Human molecular genetics 25 (15), 3383-3394, 2016 | 227 | 2016 |
Plasma proteomic associations with genetics and health in the UK Biobank BB Sun, J Chiou, M Traylor, C Benner, YH Hsu, TG Richardson, ... Nature 622 (7982), 329-338, 2023 | 211 | 2023 |
Rare variants in neuronal excitability genes influence risk for bipolar disorder SA Ament, S Szelinger, G Glusman, J Ashworth, L Hou, N Akula, ... Proceedings of the National Academy of Sciences 112 (11), 3576-3581, 2015 | 200 | 2015 |
Assessment of response to lithium maintenance treatment in bipolar disorder: a Consortium on Lithium Genetics (ConLiGen) report M Manchia, M Adli, N Akula, R Ardau, JM Aubry, L Backlund, ... PloS one 8 (6), e65636, 2013 | 186 | 2013 |
Association of polygenic score for schizophrenia and HLA antigen and inflammation genes with response to lithium in bipolar affective disorder: a genome-wide association study AT Amare, KO Schubert, L Hou, SR Clark, S Papiol, U Heilbronner, ... JAMA psychiatry 75 (1), 65-74, 2018 | 143 | 2018 |
RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder N Akula, J Barb, X Jiang, JR Wendland, KH Choi, SK Sen, L Hou, ... Molecular psychiatry 19 (11), 1179-1185, 2014 | 130 | 2014 |
Associations of PLA2G7 gene polymorphisms with plasma lipoprotein-associated phospholipase A2 activity and coronary heart disease in a Chinese Han population: the Beijing … L Hou, S Chen, H Yu, X Lu, J Chen, L Wang, J Huang, Z Fan, D Gu Human genetics 125, 11-20, 2009 | 91 | 2009 |
Genetic regulation of the human plasma proteome in 54,306 UK Biobank participants BB Sun, J Chiou, M Traylor, C Benner, YH Hsu, TG Richardson, ... BioRxiv, 2022.06. 17.496443, 2022 | 80 | 2022 |
Association of polygenic score for major depression with response to lithium in patients with bipolar disorder AT Amare, KO Schubert, L Hou, SR Clark, S Papiol, M Cearns, ... Molecular psychiatry 26 (6), 2457-2470, 2021 | 64 | 2021 |
Race, genetic ancestry and response to antidepressant treatment for major depression E Murphy, L Hou, BS Maher, G Woldehawariat, L Kassem, N Akula, ... Neuropsychopharmacology 38 (13), 2598-2606, 2013 | 58 | 2013 |
Polymorphisms of tumor necrosis factor alpha gene and coronary heart disease in a Chinese Han population: interaction with cigarette smoking L Hou, J Huang, X Lu, L Wang, Z Fan, D Gu Thrombosis research 123 (6), 822-826, 2009 | 57 | 2009 |
Variant GADL1 and response to lithium in bipolar I disorder. L Hou, U Heilbronner, M Rietschel, T Kato, PH Kuo, FJ McMahon, ... The New England journal of medicine 370 (19), 1857, 2014 | 56 | 2014 |
A genome scan for loci shared by autism spectrum disorder and language impairment CW Bartlett, L Hou, JF Flax, A Hare, SY Cheong, Z Fermano, ... American Journal of Psychiatry 171 (1), 72-81, 2014 | 51 | 2014 |
Circadian genes and lithium response in bipolar disorders: associations with PPARGC1A (PGC‐1α) and RORA PA Geoffroy, B Etain, M Lajnef, EH Zerdazi, C Brichant‐Petitjean, ... Genes, Brain and Behavior 15 (7), 660-668, 2016 | 48 | 2016 |
Sodium valproate rescues expression of TRANK1 in iPSC-derived neural cells that carry a genetic variant associated with serious mental illness X Jiang, SD Detera-Wadleigh, N Akula, BS Mallon, L Hou, T Xiao, ... Molecular psychiatry 24 (4), 613-624, 2019 | 42 | 2019 |
Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients KO Schubert, A Thalamuthu, AT Amare, J Frank, F Streit, M Adl, N Akula, ... Translational Psychiatry 11 (1), 606, 2021 | 36 | 2021 |
Gene× gene interaction in shared etiology of autism and specific language impairment CW Bartlett, JF Flax, Z Fermano, A Hare, L Hou, SA Petrill, S Buyske, ... Biological psychiatry 72 (8), 692-699, 2012 | 36 | 2012 |
Analysis of the influence of microRNAs in lithium response in bipolar disorder CS Reinbold, AJ Forstner, J Hecker, JM Fullerton, P Hoffmann, L Hou, ... Frontiers in psychiatry 9, 207, 2018 | 33 | 2018 |
Exome sequencing of a large family identifies potential candidate genes contributing risk to bipolar disorder T Zhang, L Hou, DT Chen, FJ McMahon, JC Wang, JP Rice Gene 645, 119-123, 2018 | 33 | 2018 |