Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease JV Andersen, SK Christensen, EW Westi, M Diaz-delCastillo, H Tanila, ... Neurobiology of disease 148, 105198, 2021 | 65 | 2021 |
Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease JV Andersen, NH Skotte, SK Christensen, FS Polli, M Shabani, ... Cell Death & Disease 12 (11), 954, 2021 | 51 | 2021 |
Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply JV Andersen, EW Westi, E Jakobsen, N Urruticoechea, K Borges, ... Molecular brain 14, 1-13, 2021 | 48 | 2021 |
Extensive astrocyte metabolism of γ‐aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex JV Andersen, E Jakobsen, EW Westi, MEK Lie, CM Voss, BI Aldana, ... Glia 68 (12), 2601-2612, 2020 | 35 | 2020 |
Neuronal loss of the glutamate transporter GLT-1 promotes excitotoxic injury in the hippocampus TS Rimmele, S Li, JV Andersen, EW Westi, A Rotenberg, J Wang, ... Frontiers in Cellular Neuroscience 15, 788262, 2021 | 18 | 2021 |
β-Hydroxybutyrate and medium-chain fatty acids are metabolized by different cell types in mouse cerebral cortex slices JV Andersen, EW Westi, ES Neal, BI Aldana, K Borges Neurochemical Research 48 (1), 54-61, 2023 | 13 | 2023 |
Divergent cellular energetics, glutamate metabolism, and mitochondrial function between human and mouse cerebral cortex EW Westi, E Jakobsen, CM Voss, LK Bak, LH Pinborg, BI Aldana, ... Molecular Neurobiology 59 (12), 7495-7512, 2022 | 10 | 2022 |
Using stable isotope tracing to unravel the metabolic components of neurodegeneration: Focus on neuron-glia metabolic interactions EW Westi, JV Andersen, BI Aldana Neurobiology of Disease 182, 106145, 2023 | 8 | 2023 |
Decreased glucose metabolism and glutamine synthesis in the retina of a transgenic mouse model of Alzheimer’s disease ALM Tams, B Sanz-Morello, EW Westi, ZA Mouhammad, JV Andersen, ... Cellular and Molecular Neurobiology 42, 291-303, 2022 | 6 | 2022 |
Deletion of CaMKIIα disrupts glucose metabolism, glutamate uptake, and synaptic energetics in the cerebral cortex JV Andersen, EW Westi, N Griem‐Krey, NH Skotte, A Schousboe, ... Journal of Neurochemistry 168 (5), 704-718, 2024 | 2 | 2024 |
Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3 H Haukedal, SS Lorenzen, EW Westi, GI Corsi, VP Gadekar, A McQuade, ... Brain, Behavior, and Immunity 113, 353-373, 2023 | 2 | 2023 |
Deficient brain GABA metabolism leads to widespread impairments of astrocyte and oligodendrocyte function JV Andersen, OC Marian, FL Qvist, EW Westi, BI Aldana, A Schousboe, ... Glia, 2024 | | 2024 |