Novel strategies to address the challenges in top-down proteomics JA Melby, DS Roberts, EJ Larson, KA Brown, EF Bayne, S Jin, Y Ge Journal of the American Society for Mass Spectrometry 32 (6), 1278-1294, 2021 | 163 | 2021 |
Simulation of elution profiles in liquid chromatography− II: Investigation of injection volume overload under gradient elution conditions applied to second dimension … DR Stoll, RW Sajulga, BN Voigt, EJ Larson, LN Jeong, SC Rutan Journal of Chromatography A 1523, 162-172, 2017 | 70 | 2017 |
Structural O-glycoform heterogeneity of the SARS-CoV-2 spike protein receptor-binding domain revealed by top-down mass spectrometry DS Roberts, M Mann, JA Melby, EJ Larson, Y Zhu, AR Brasier, S Jin, Y Ge Journal of the American Chemical Society 143 (31), 12014-12024, 2021 | 69 | 2021 |
High-throughput multi-attribute analysis of antibody-drug conjugates enabled by trapped ion mobility spectrometry and top-down mass spectrometry EJ Larson, DS Roberts, JA Melby, KM Buck, Y Zhu, S Zhou, L Han, ... Analytical chemistry 93 (29), 10013-10021, 2021 | 39 | 2021 |
Optimization of a two-dimensional liquid chromatography-supercritical fluid chromatography-mass spectrometry (2D-LC-SFC-MS) system to assess “in-vivo” inter-conversion of … M Goel, E Larson, CJ Venkatramani, MA Al-Sayah Journal of Chromatography B 1084, 89-95, 2018 | 37 | 2018 |
High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms JA Melby, KA Brown, ZR Gregorich, DS Roberts, EA Chapman, LE Ehlers, ... Proceedings of the National Academy of Sciences 120 (19), e2222081120, 2023 | 34 | 2023 |
Middle-down multi-attribute analysis of antibody-drug conjugates with electron transfer dissociation B Chen, Z Lin, Y Zhu, Y Jin, E Larson, Q Xu, C Fu, Z Zhang, Q Zhang, ... Analytical chemistry 91 (18), 11661-11669, 2019 | 30 | 2019 |
Implications of dispersion in connecting capillaries for separation systems involving post-column flow splitting C Gunnarson, T Lauer, H Willenbring, E Larson, M Dittmann, ... Journal of Chromatography A 1639, 461893, 2021 | 22 | 2021 |
MASH Native: a unified solution for native top-down proteomics data processing EJ Larson, MR Pergande, ME Moss, KJ Rossler, RK Wenger, B Krichel, ... Bioinformatics 39 (6), btad359, 2023 | 18 | 2023 |
Rapid analysis of reduced antibody drug conjugate by online LC-MS/MS with fourier transform Ion cyclotron resonance mass spectrometry EJ Larson, Y Zhu, Z Wu, B Chen, Z Zhang, S Zhou, L Han, Q Zhang, Y Ge Analytical chemistry 92 (22), 15096-15103, 2020 | 12 | 2020 |
Comprehensive characterization of endogenous phospholamban proteoforms enabled by photocleavable surfactant and top-down proteomics HT Rogers, DS Roberts, EJ Larson, JA Melby, KJ Rossler, AV Carr, ... Analytical Chemistry 95 (35), 13091-13100, 2023 | 5 | 2023 |
Rbm20 ablation is associated with changes in the expression of titin-interacting and metabolic proteins EJ Larson, ZR Gregorich, Y Zhang, BH Li, TJ Aballo, JA Melby, Y Ge, ... Molecular omics 18 (7), 627-634, 2022 | 5 | 2022 |
Small-Scale Serial Size Exclusion Chromatography (s3SEC) for High Sensitivity Top-Down Proteomics of Large Proteoforms HT Rogers, JA Melby, LE Ehlers, MS Fischer, EJ Larson, Z Gao, ... Analytical Chemistry 96 (7), 2748-2753, 2024 | 4 | 2024 |
Online mixed-bed ion exchange chromatography for native top-down proteomics of complex mixtures MS Fischer, HT Rogers, EA Chapman, HJ Chan, B Krichel, Z Gao, ... Journal of Proteome Research 23 (7), 2315-2322, 2024 | 2 | 2024 |
Automated multicolumn screening workflow in ultra-high pressure hydrophilic interaction chromatography for streamlined method development of polar analytes M Hemida, RC Barrientos, AN Singh, GL Losacco, H Wang, D Guillarme, ... Journal of Chromatography A 1733, 465266, 2024 | 1 | 2024 |
Integrated proteomics and transcriptomics analysis reveals insights into differences in premature mortality associated with disparate pathogenic RBM20 variants ZR Gregorich, EJ Larson, Y Zhang, CU Braz, C Liu, Y Ge, W Guo Journal of Molecular and Cellular Cardiology 197, 78-89, 2024 | | 2024 |
Two-Dimensional Size Exclusion-Reversed Phase Liquid Chromatography for Quantitative Analysis of L1 Proteins in Complex Vaccine Matrices AJ Arcinas, EJ Larson, EP Buchhalter, ZD Dunn, H Wang, AN Singh, ... | | 2024 |
New Front-end Separation Approaches for Top-down Proteomics E Larson University of Wisconsin--Madison, 2023 | | 2023 |
Abstract P2070: Insights Into RBM20 Cardiomyopathy Revealed By Global Proteomics ZR Gregorich, EJ Larson, Y Zhang, Y Ge, W Guo Circulation Research 131 (Suppl_1), AP2070-AP2070, 2022 | | 2022 |
Recent advances in two-dimensional liquid chromatography D Stoll, J Halvorson, E Larson, D Harmes, S Rutan ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |