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Eli J. Larson
Eli J. Larson
Senior Scientist, Merck & Co. Inc.
在 merck.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Novel strategies to address the challenges in top-down proteomics
JA Melby, DS Roberts, EJ Larson, KA Brown, EF Bayne, S Jin, Y Ge
Journal of the American Society for Mass Spectrometry 32 (6), 1278-1294, 2021
1632021
Simulation of elution profiles in liquid chromatography− II: Investigation of injection volume overload under gradient elution conditions applied to second dimension …
DR Stoll, RW Sajulga, BN Voigt, EJ Larson, LN Jeong, SC Rutan
Journal of Chromatography A 1523, 162-172, 2017
702017
Structural O-glycoform heterogeneity of the SARS-CoV-2 spike protein receptor-binding domain revealed by top-down mass spectrometry
DS Roberts, M Mann, JA Melby, EJ Larson, Y Zhu, AR Brasier, S Jin, Y Ge
Journal of the American Chemical Society 143 (31), 12014-12024, 2021
692021
High-throughput multi-attribute analysis of antibody-drug conjugates enabled by trapped ion mobility spectrometry and top-down mass spectrometry
EJ Larson, DS Roberts, JA Melby, KM Buck, Y Zhu, S Zhou, L Han, ...
Analytical chemistry 93 (29), 10013-10021, 2021
392021
Optimization of a two-dimensional liquid chromatography-supercritical fluid chromatography-mass spectrometry (2D-LC-SFC-MS) system to assess “in-vivo” inter-conversion of …
M Goel, E Larson, CJ Venkatramani, MA Al-Sayah
Journal of Chromatography B 1084, 89-95, 2018
372018
High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms
JA Melby, KA Brown, ZR Gregorich, DS Roberts, EA Chapman, LE Ehlers, ...
Proceedings of the National Academy of Sciences 120 (19), e2222081120, 2023
342023
Middle-down multi-attribute analysis of antibody-drug conjugates with electron transfer dissociation
B Chen, Z Lin, Y Zhu, Y Jin, E Larson, Q Xu, C Fu, Z Zhang, Q Zhang, ...
Analytical chemistry 91 (18), 11661-11669, 2019
302019
Implications of dispersion in connecting capillaries for separation systems involving post-column flow splitting
C Gunnarson, T Lauer, H Willenbring, E Larson, M Dittmann, ...
Journal of Chromatography A 1639, 461893, 2021
222021
MASH Native: a unified solution for native top-down proteomics data processing
EJ Larson, MR Pergande, ME Moss, KJ Rossler, RK Wenger, B Krichel, ...
Bioinformatics 39 (6), btad359, 2023
182023
Rapid analysis of reduced antibody drug conjugate by online LC-MS/MS with fourier transform Ion cyclotron resonance mass spectrometry
EJ Larson, Y Zhu, Z Wu, B Chen, Z Zhang, S Zhou, L Han, Q Zhang, Y Ge
Analytical chemistry 92 (22), 15096-15103, 2020
122020
Comprehensive characterization of endogenous phospholamban proteoforms enabled by photocleavable surfactant and top-down proteomics
HT Rogers, DS Roberts, EJ Larson, JA Melby, KJ Rossler, AV Carr, ...
Analytical Chemistry 95 (35), 13091-13100, 2023
52023
Rbm20 ablation is associated with changes in the expression of titin-interacting and metabolic proteins
EJ Larson, ZR Gregorich, Y Zhang, BH Li, TJ Aballo, JA Melby, Y Ge, ...
Molecular omics 18 (7), 627-634, 2022
52022
Small-Scale Serial Size Exclusion Chromatography (s3SEC) for High Sensitivity Top-Down Proteomics of Large Proteoforms
HT Rogers, JA Melby, LE Ehlers, MS Fischer, EJ Larson, Z Gao, ...
Analytical Chemistry 96 (7), 2748-2753, 2024
42024
Online mixed-bed ion exchange chromatography for native top-down proteomics of complex mixtures
MS Fischer, HT Rogers, EA Chapman, HJ Chan, B Krichel, Z Gao, ...
Journal of Proteome Research 23 (7), 2315-2322, 2024
22024
Automated multicolumn screening workflow in ultra-high pressure hydrophilic interaction chromatography for streamlined method development of polar analytes
M Hemida, RC Barrientos, AN Singh, GL Losacco, H Wang, D Guillarme, ...
Journal of Chromatography A 1733, 465266, 2024
12024
Integrated proteomics and transcriptomics analysis reveals insights into differences in premature mortality associated with disparate pathogenic RBM20 variants
ZR Gregorich, EJ Larson, Y Zhang, CU Braz, C Liu, Y Ge, W Guo
Journal of Molecular and Cellular Cardiology 197, 78-89, 2024
2024
Two-Dimensional Size Exclusion-Reversed Phase Liquid Chromatography for Quantitative Analysis of L1 Proteins in Complex Vaccine Matrices
AJ Arcinas, EJ Larson, EP Buchhalter, ZD Dunn, H Wang, AN Singh, ...
2024
New Front-end Separation Approaches for Top-down Proteomics
E Larson
University of Wisconsin--Madison, 2023
2023
Abstract P2070: Insights Into RBM20 Cardiomyopathy Revealed By Global Proteomics
ZR Gregorich, EJ Larson, Y Zhang, Y Ge, W Guo
Circulation Research 131 (Suppl_1), AP2070-AP2070, 2022
2022
Recent advances in two-dimensional liquid chromatography
D Stoll, J Halvorson, E Larson, D Harmes, S Rutan
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016
2016
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