IL-7R-mediated signaling in T-cell acute lymphoblastic leukemia: An update ML Oliveira, P Akkapeddi, D Ribeiro, A Melão, JT Barata Advances in biological regulation 71, 88-96, 2019 | 98 | 2019 |
Adult B-cell acute lymphoblastic leukemia cells display decreased PTEN activity and constitutive hyperactivation of PI3K/Akt pathway despite high PTEN protein levels AM Gomes, MVD Soares, P Ribeiro, J Caldas, V Póvoa, LR Martins, ... Haematologica 99 (6), 1062, 2014 | 98 | 2014 |
STAT5 is essential for IL-7–mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells D Ribeiro, A Melão, R van Boxtel, CI Santos, A Silva, MC Silva, ... Blood Advances 2 (17), 2199-2213, 2018 | 87 | 2018 |
IL-7R-mediated signaling in T-cell acute lymphoblastic leukemia D Ribeiro, A Melão, JT Barata Advances in biological regulation 53 (2), 211-222, 2013 | 79 | 2013 |
Activity of the clinical-stage CK2-specific inhibitor CX-4945 against chronic lymphocytic leukemia LR Martins, P Lúcio, A Melao, I Antunes, BA Cardoso, R Stansfield, ... Leukemia 28 (1), 179-182, 2014 | 77 | 2014 |
Q192R polymorphism of the paraoxonase-1 gene as a risk factor for obesity in Portuguese women L Veiga, J Silva-Nunes, A Melao, A Oliveira, L Duarte, M Brito European journal of endocrinology 164 (2), 213-218, 2011 | 48 | 2011 |
Study of the antidiabetic capacity of the VO (dmpp) 2 complex M Passadouro, AM Metelo, AS Melão, JR Pedro, H Faneca, E Carvalho, ... Journal of inorganic biochemistry 104 (9), 987-992, 2010 | 42 | 2010 |
microRNAs regulate TAL1 expression in T-cell acute lymphoblastic leukemia NC Correia, A Melão, V Póvoa, L Sarmento, MG de Cedrón, M Malumbres, ... Oncotarget 7 (7), 8268, 2016 | 36 | 2016 |
Effects of cyclosporine and sirolimus on insulin-stimulated glucose transport and glucose tolerance in a rat model P Lopes, A Fuhrmann, J Sereno, MJ Pereira, P Nunes, J Pedro, A Melao, ... Transplantation proceedings 45 (3), 1142-1148, 2013 | 23 | 2013 |
Optimal interleukin-7 receptor-mediated signaling, cell cycle progression and viability of T-cell acute lymphoblastic leukemia cells rely on casein kinase 2 activity A Melão, M Spit, BA Cardoso, JT Barata Haematologica 101 (11), 1368, 2016 | 20 | 2016 |
Clinical-grade peptide-based inhibition of CK2 blocks viability and proliferation of T-ALL cells and counteracts IL-7 stimulation and stromal support Y Perera, A Melão, AC Ramón, D Vázquez, D Ribeiro, SE Perea, ... Cancers 12 (6), 1377, 2020 | 16 | 2020 |
Factors related with adiponectinemia in obese and normal-weight women and with its variation in weight loss programs J Silva-Nunes, A Oliveira, L Duarte, M Barradas, A Melão, M Brito, L Veiga Obesity facts 6 (2), 124-133, 2013 | 15 | 2013 |
In Vitro and in Vivo Targeting of Chronic Lymphocytic Leukemia Using CX-4945, a Clinical-Stage CK2-Specific Inhibitor. LR Martins, P Lúcio, A Melao, BA Cardoso, R Stansfield, D Drygin, ... Blood 120 (21), 2897, 2012 | 3 | 2012 |
IL-7 activates a STAT5/PIM1 axis to promote T-cell acute lymphoblastic leukemia proliferation and viability in a bcl-2-independent manner R Daniel, A Melão, R van Boxtel, C Santos, A Silva, MC Silva, ... Blood 132, 914, 2018 | 2 | 2018 |
CK2 Basal Activity Regulates IL-7-Mediated JAK/STAT and PI3K/Akt Pathway Activation and Pro-Survival Effects in T-Cell Acute Lymphoblastic Leukemia Cells A Melao, A Girio, JT Barata Blood 120 (21), 1242, 2012 | 1 | 2012 |
Anthropometric determinants of adiponectin levels in obese and non obese premenopausal women J Silva-Nunes, L Duarte, L Veiga, A Melao, M Brito, F Malheiro Endocrine Abstracts 20, 2009 | 1 | 2009 |
Dependence of IL-7R-Mediated Signaling on Sphingosine Kinase Activity in Acute Lymphoblastic Leukemia, but Not Healthy Lymphoid Cells, Is an Exploitable Therapeutic Vulnerability MB Fernandes, A Melão, T Araújo, A Cachucho, DR Adams, J Oh, ... Blood 142, 38, 2023 | | 2023 |
Exploring the role of IL-7, CK2, and SphK in T-cell acute lymphoblastic leukemia A Melão | | 2020 |
OptimalIL-7R-mediatedsignaling, cellcycleprogressionandviabilityofT-cellacute lymphoblasticleukemiacellsrelyonCK2activity A Melão, M Spit, BA Cardoso, JT Barata | | 2016 |
IL-7 ACTIVATES THE JAK/STAT5/PIM1 KINASE AXIS THEREBY MEDIATING VIABILITY AND GROWTH OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA CELLS D Ribeiro, A Melao, R van Boxtel, CI Santos, MC Silva, A Silva, ... HAEMATOLOGICA 100, 198-199, 2015 | | 2015 |