A first-in-human Phase I trial of the oral p-STAT3 inhibitor WP1066 in patients with recurrent malignant glioma J Groot, M Ott, J Wei, C Kassab, D Fang, H Najem, B O'Brien, ... CNS oncology 11 (02), CNS87, 2022 | 32 | 2022 |
Intratumoral delivery of STING agonist results in clinical responses in canine glioblastoma CE Boudreau, H Najem, M Ott, C Horbinski, D Fang, CM DeRay, ... Clinical Cancer Research 27 (20), 5528-5535, 2021 | 32 | 2021 |
New approaches to glioblastoma M Khasraw, Y Fujita, C Lee-Chang, IV Balyasnikova, H Najem, ... Annual review of medicine 73 (1), 279-292, 2022 | 20 | 2022 |
The eclectic nature of glioma-infiltrating macrophages and microglia VA Arrieta, H Najem, E Petrosyan, C Lee-Chang, P Chen, AM Sonabend, ... International journal of molecular sciences 22 (24), 13382, 2021 | 17 | 2021 |
Immune microenvironment landscape in CNS tumors and role in responses to immunotherapy H Najem, M Khasraw, AB Heimberger Cells 10 (8), 2032, 2021 | 15 | 2021 |
Central nervous system immune interactome is a function of cancer lineage, tumor microenvironment, and STAT3 expression H Najem, M Ott, C Kassab, A Rao, G Rao, A Marisetty, AM Sonabend, ... JCI insight 7 (9), 2022 | 13 | 2022 |
Macrophage–endothelial cell crosstalk orchestrates neutrophil recruitment in inflamed mucosa X Ren, LD Manzanares, EB Piccolo, JM Urbanczyk, DP Sullivan, ... The Journal of Clinical Investigation 133 (15), 2023 | 10 | 2023 |
Cell-directed aptamer therapeutic targeting for cancers including those within the central nervous system J Wei, R Song, A Sabbagh, A Marisetty, N Shukla, D Fang, H Najem, M Ott, ... Oncoimmunology 11 (1), 2062827, 2022 | 6 | 2022 |
Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas MW Youngblood, Z Erson-Omay, C Li, H Najem, S Coșkun, E Tyrtova, ... Nature communications 14 (1), 6279, 2023 | 5 | 2023 |
NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy A Choudhury, MA Cady, CHG Lucas, H Najem, JJ Phillips, B Palikuqi, ... bioRxiv, 2023 | 5 | 2023 |
Clinical management of supratentorial non-skull base meningiomas A Adekanmbi, MW Youngblood, CL Karras, EA Oyetunji, J Kalapurakal, ... Cancers 14 (23), 5887, 2022 | 5 | 2022 |
cGAS-STING pathway targeted therapies and their applications in the treatment of high-grade glioma S Tripathi, H Najem, AS Mahajan, P Zhang, JT Low, AH Stegh, MA Curran, ... F1000Research 11, 2022 | 5 | 2022 |
CD11c+ CD163+ Cells and signal transducer and activator of transcription 3 (STAT3) expression are common in melanoma leptomeningeal disease H Najem, A Marisetty, C Horbinski, J Long, JT Huse, IC Glitza Oliva, ... Frontiers in immunology 12, 745893, 2021 | 5 | 2021 |
Spatial genomic, biochemical, and cellular mechanisms drive meningioma heterogeneity and evolution CH Lucas, K Mirchia, K Seo, H Najem, W Chen, N Zakimi, A Choudhury, ... Research Square, 2023 | 4 | 2023 |
Immunobiology and Cytokine Modulation of the Pediatric Brain Tumor Microenvironment: A Scoping Review S Budhiraja, H Najem, S Tripathi, NR Wadhawani, C Horbinski, M McCord, ... Cancers 15 (14), 3655, 2023 | 3 | 2023 |
Myeloid cell classification and therapeutic opportunities within the glioblastoma tumor microenvironment in the single cell-omics era CJ Larkin, VA Arrieta, H Najem, G Li, P Zhang, J Miska, P Chen, ... Frontiers in immunology 13, 907605, 2022 | 3 | 2022 |
The Use of Targeted Cytokines as Cancer Therapeutics in Glioblastoma M Sooreshjani, S Tripathi, C Dussold, H Najem, J de Groot, RV Lukas, ... Cancers 15 (14), 3739, 2023 | 2 | 2023 |
Genome Characterization of Bird-Related Rhabdoviruses Circulating in Africa DS Luo, ZJ Zhou, XY Ge, H Bourhy, ZL Shi, M Grandadam, L Dacheux Viruses 13 (11), 2168, 2021 | 2 | 2021 |
Cancer-associated fibroblast–secreted collagen is associated with immune inhibitor receptor LAIR1 in gliomas S Tripathi, H Najem, C Dussold, S Pacheco, J Miska, K McCortney, ... Journal of Clinical Investigation 134 (4), e176613, 2024 | 1 | 2024 |
A Case Study of Chimeric Antigen Receptor T Cell Function: Donor Therapeutic Differences in Activity and Modulation with Verteporfin J Liang, D Fang, J Gumin, H Najem, M Sooreshjani, R Song, A Sabbagh, ... Cancers 15 (4), 1085, 2023 | 1 | 2023 |