Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor JL Rogers, L Bayeh, TH Scheuermann, J Longgood, J Key, J Naidoo, ... Journal of medicinal chemistry 56 (4), 1739-1747, 2013 | 147 | 2013 |
Catalytic allylic oxidation of internal alkenes to a multifunctional chiral building block L Bayeh, PQ Le, UK Tambar Nature 547 (7662), 196-200, 2017 | 102 | 2017 |
Copper hydride catalyzed enantioselective synthesis of axially chiral 1, 3-disubstituted allenes L Bayeh-Romero, SL Buchwald Journal of the American Chemical Society 141 (35), 13788-13794, 2019 | 85 | 2019 |
Isoform-selective and stereoselective inhibition of hypoxia inducible factor-2 TH Scheuermann, D Stroud, CE Sleet, L Bayeh, C Shokri, H Wang, ... Journal of Medicinal Chemistry 58 (15), 5930-5941, 2015 | 83 | 2015 |
A new paradigm for GERD pathogenesis. Not acid injury, but cytokine-mediated inflammation driven by HIF-2α: a potential role for targeting HIF-2α to prevent and treat reflux … RF Souza, L Bayeh, SJ Spechler, UK Tambar, RK Bruick Current opinion in pharmacology 37, 93-99, 2017 | 63 | 2017 |
Synthesis and biochemical evaluation of thiochromanone thiosemicarbazone analogues as inhibitors of cathepsin L J Song, LM Jones, GDK Kumar, ES Conner, L Bayeh, GE Chavarria, ... ACS medicinal chemistry letters 3 (6), 450-453, 2012 | 46 | 2012 |
Small-molecule inhibitors of cathepsin L incorporating functionalized ring-fused molecular frameworks J Song, LM Jones, GE Chavarria, AK Charlton-Sevcik, A Jantz, ... Bioorganic & medicinal chemistry letters 23 (9), 2801-2807, 2013 | 43 | 2013 |
Catalytic asymmetric intermolecular allylic functionalization of unactivated internal alkenes L Bayeh, UK Tambar ACS catalysis 7 (12), 8533-8543, 2017 | 31 | 2017 |
Allylic functionalization of unactivated olefins with Grignard reagents H Bao, L Bayeh, UK Tambar Angewandte Chemie 126 (6), 1690-1694, 2014 | 30 | 2014 |
Catalytic chemo-, regio-, diastereo-, and enantioselective bromochlorination of unsaturated systems enabled by Lewis base-controlled chloride release AE Lubaev, MD Rathnayake, F Eze, L Bayeh-Romero Journal of the American Chemical Society 144 (29), 13294-13301, 2022 | 23 | 2022 |
Regioselective and diastereoselective aminoarylation of 1, 3-dienes H Bao, L Bayeh, UK Tambar Chemical Science 5 (12), 4863-4867, 2014 | 22 | 2014 |
Catalytic enantioselective allylic amination of olefins for the synthesis of ent-sitagliptin H Bao, L Bayeh, UK Tambar Synlett 24 (18), 2459-2463, 2013 | 20 | 2013 |
Expanding Zirconocene Hydride Catalysis: In Situ Generation and Turnover of ZrH Catalysts Enabling Catalytic Carbonyl Reductions RA Kehner, MC Hewitt, L Bayeh-Romero ACS catalysis 12 (3), 1758-1763, 2022 | 16 | 2022 |
Mild divergent semireductive transformations of secondary and tertiary amides via zirconocene hydride catalysis RA Kehner, G Zhang, L Bayeh-Romero Journal of the American Chemical Society 145 (9), 4921-4927, 2023 | 15 | 2023 |
Selective zirconocene hydride-catalyzed semi-hydrogenation of terminal alkynes RA Kehner, AE Lubaev, MD Rathnayake, R Loden, G Zhang, ... Tetrahedron 133, 133267, 2023 | 9 | 2023 |
ZrH-Catalyzed Semi-Reduction of Esters Enabled by an Imine/Enamine Trap R Kehner, L Bayeh-Romero | | 2024 |
Direct conversion of esters to imines/enamines and applications to polyester waste upcycling RA Kehner, W Huang, L Bayeh-Romero Chemical Science 15 (41), 16947-16953, 2024 | | 2024 |
Copper Hydride-Catalyzed Enantioselective Synthesis of Axially Chiral 1, 3-Disubstituted Allenes L Bayeh, SL Buchwald | | 2019 |
Synthetic Studies in the Selective Functionalization of Unsaturated Compounds: From Initial Applications in Medicinal Chemistry to General Applications in Unactivated Systems LA Bayeh | | 2016 |
Allylic functionalization of unactivated olefins with Grignard reagents L Bayeh, H Bao, U Tambar ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014 | | 2014 |