Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease CH Wiegman, C Michaeloudes, G Haji, P Narang, CJ Clarke, KE Russell, ... Journal of Allergy and Clinical Immunology 136 (3), 769-780, 2015 | 452 | 2015 |
TGF-β regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells C Michaeloudes, MB Sukkar, NM Khorasani, PK Bhavsar, KF Chung American Journal of Physiology-Lung Cellular and Molecular Physiology 300 (2 …, 2011 | 218 | 2011 |
Molecular mechanisms of oxidative stress in asthma C Michaeloudes, H Abubakar-Waziri, R Lakhdar, K Raby, P Dixey, ... Molecular aspects of medicine 85, 101026, 2022 | 138 | 2022 |
Mesenchymal stem cells alleviate oxidative stress–induced mitochondrial dysfunction in the airways X Li, C Michaeloudes, Y Zhang, CH Wiegman, IM Adcock, Q Lian, ... Journal of Allergy and Clinical Immunology 141 (5), 1634-1645. e5, 2018 | 128 | 2018 |
Hydrogen sulfide inhibits proliferation and release of IL-8 from human airway smooth muscle cells MM Perry, CK Hui, M Whiteman, ME Wood, I Adcock, P Kirkham, ... American journal of respiratory cell and molecular biology 45 (4), 746-752, 2011 | 110 | 2011 |
Corticosteroid insensitivity of chemokine expression in airway smooth muscle of patients with severe asthma PJ Chang, PK Bhavsar, C Michaeloudes, N Khorasani, KF Chung Journal of Allergy and Clinical Immunology 130 (4), 877-885. e5, 2012 | 95 | 2012 |
Transforming growth factor-β and nuclear factor E2–related factor 2 regulate antioxidant responses in airway smooth muscle cells: role in asthma C Michaeloudes, PJ Chang, M Petrou, KF Chung American journal of respiratory and critical care medicine 184 (8), 894-903, 2011 | 89 | 2011 |
Impaired nuclear translocation of the glucocorticoid receptor in corticosteroid-insensitive airway smooth muscle in severe asthma PJ Chang, C Michaeloudes, J Zhu, N Shaikh, J Baker, KF Chung, ... American journal of respiratory and critical care medicine 191 (1), 54-62, 2015 | 73 | 2015 |
Role of metabolic reprogramming in pulmonary innate immunity and its impact on lung diseases C Michaeloudes, PK Bhavsar, S Mumby, B Xu, CKM Hui, KF Chung, ... Journal of Innate Immunity 12 (1), 31-46, 2020 | 72 | 2020 |
Bromodomain and extraterminal proteins suppress NF-E2–related factor 2–mediated antioxidant gene expression C Michaeloudes, N Mercado, C Clarke, PK Bhavsar, IM Adcock, ... The Journal of Immunology 192 (10), 4913-4920, 2014 | 72 | 2014 |
Metabolic re-patterning in COPD airway smooth muscle cells C Michaeloudes, CH Kuo, G Haji, DK Finch, AJ Halayko, P Kirkham, ... European Respiratory Journal 50 (5), 2017 | 63 | 2017 |
Increased phenotypic differentiation and reduced corticosteroid sensitivity of fibrocytes in severe asthma CY Lo, C Michaeloudes, PK Bhavsar, CD Huang, CH Wang, HP Kuo, ... Journal of Allergy and Clinical Immunology 135 (5), 1186-1195. e6, 2015 | 48 | 2015 |
Mitochondrial dysfunction in airways and quadriceps muscle of patients with chronic obstructive pulmonary disease G Haji, CH Wiegman, C Michaeloudes, MS Patel, K Curtis, P Bhavsar, ... Respiratory Research 21, 1-11, 2020 | 44 | 2020 |
Bromodomain and extraterminal (BET) protein inhibition restores redox balance and inhibits myofibroblast activation CJW Stock, C Michaeloudes, P Leoni, AL Durham, S Mumby, AU Wells, ... BioMed Research International 2019 (1), 1484736, 2019 | 30 | 2019 |
DNA methylation modules in airway smooth muscle are associated with asthma severity MM Perry, P Lavender, CS Kuo, F Galea, C Michaeloudes, JM Flanagan, ... European Respiratory Journal 51 (4), 2018 | 28 | 2018 |
Dealing with stress: defective metabolic adaptation in chronic obstructive pulmonary disease pathogenesis C Michaeloudes, PK Bhavsar, S Mumby, KF Chung, IM Adcock Annals of the American Thoracic Society 14 (Supplement 5), S374-S382, 2017 | 21 | 2017 |
Mechanisms of airway epithelial injury and abnormal repair in asthma and COPD KL Raby, C Michaeloudes, J Tonkin, KF Chung, PK Bhavsar Frontiers in Immunology 14, 1201658, 2023 | 17 | 2023 |
Oxidants induce a corticosteroid-insensitive phosphorylation of histone 3 at serine 10 in monocytes JA Marwick, C Tudor, N Khorasani, C Michaeloudes, PK Bhavsar, ... PLoS One 10 (4), e0124961, 2015 | 14 | 2015 |
Study of mesenchymal stem cell-mediated mitochondrial transfer in in vitro models of oxidant-mediated airway epithelial and smooth muscle cell injury C Michaeloudes, X Li, JCW Mak, PK Bhavsar In Vitro Models for Stem Cell Therapy: Methods and Protocols, 93-105, 2021 | 11 | 2021 |
ORMDL3 regulates cigarette smoke–induced endoplasmic reticulum stress in airway smooth muscle cells R Chen, C Michaeloudes, Y Liang, PK Bhavsar, KF Chung, MSM Ip, ... Journal of Allergy and Clinical Immunology 149 (4), 1445-1457. e5, 2022 | 10 | 2022 |