Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 1768 | 2019 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 808 | 2017 |
New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 414 | 2022 |
Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study L Hou, U Heilbronner, F Degenhardt, M Adli, K Akiyama, N Akula, ... The Lancet 387 (10023), 1085-1093, 2016 | 344 | 2016 |
Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder L Hou, SE Bergen, N Akula, J Song, CM Hultman, M Landén, M Adli, ... Human molecular genetics 25 (15), 3383-3394, 2016 | 198 | 2016 |
Assessment of response to lithium maintenance treatment in bipolar disorder: a Consortium on Lithium Genetics (ConLiGen) report M Manchia, M Adli, N Akula, R Ardau, JM Aubry, L Backlund, ... PloS one 8 (6), e65636, 2013 | 169 | 2013 |
Realities and expectations of pharmacogenomics and personalized medicine: impact of translating genetic knowledge into clinical practice A Squassina, M Manchia, VG Manolopoulos, M Artac, C Lappa-Manakou, ... Pharmacogenomics 11 (8), 1149-1167, 2010 | 163 | 2010 |
The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatment TG Schulze, M Alda, M Adli, N Akula, R Ardau, ET Bui, C Chillotti, ... Neuropsychobiology 62 (1), 72-78, 2010 | 156 | 2010 |
Association of polygenic score for schizophrenia and HLA antigen and inflammation genes with response to lithium in bipolar affective disorder: a genome-wide association study AT Amare, KO Schubert, L Hou, SR Clark, S Papiol, U Heilbronner, ... JAMA psychiatry 75 (1), 65-74, 2018 | 124 | 2018 |
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores I De Rojas, S Moreno-Grau, N Tesi, B Grenier-Boley, V Andrade, ... Nature communications 12 (1), 3417, 2021 | 118 | 2021 |
A European spectrum of pharmacogenomic biomarkers: implications for clinical pharmacogenomics C Mizzi, E Dalabira, J Kumuthini, N Dzimiri, I Balogh, N Başak, R Böhm, ... PloS one 11 (9), e0162866, 2016 | 108 | 2016 |
Evidence for association of an ACCN1 gene variant with response to lithium treatment in Sardinian patients with bipolar disorder A Squassina, M Manchia, J Borg, D Congiu, M Costa, M Georgitsi, ... Pharmacogenomics 12 (11), 1559-1569, 2011 | 98 | 2011 |
SIRT1, miR-132 and miR-212 link human longevity to Alzheimer’s Disease A Hadar, E Milanesi, M Walczak, M Puzianowska-Kuźnicka, J Kuźnicki, ... Scientific reports 8 (1), 8465, 2018 | 85 | 2018 |
Association study in a Sardinian sample between bipolar disorder and the nuclear receptor REV‐ERBα gene, a critical component of the circadian clock system G Severino, M Manchia, P Contu, A Squassina, S Lampus, R Ardau, ... Bipolar disorders 11 (2), 215-220, 2009 | 84 | 2009 |
Insulin-like growth factor 1 (IGF-1) expression is up-regulated in lymphoblastoid cell lines of lithium responsive bipolar disorder patients A Squassina, M Costa, D Congiu, M Manchia, A Angius, V Deiana, ... Pharmacological research 73, 1-7, 2013 | 74 | 2013 |
Alzheimer Disease Genetics Consortium (ADGC); European Alzheimer’s Disease Initiative (EADI); Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE … BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nat Genet 51 (3), 414-430, 2019 | 72 | 2019 |
Linkage of M5 muscarinic and α7-nicotinic receptor genes on 15q13 to schizophrenia V De Luca, H Wang, A Squassina, GWH Wong, J Yeomans, JL Kennedy Neuropsychobiology 50 (2), 124-127, 2004 | 69 | 2004 |
Association study of brain‐derived neurotrophic factor (BDNF) and LIN‐7 homolog (LIN‐7) genes with adult attention‐deficit/hyperactivity disorder M Lanktree, A Squassina, M Krinsky, J Strauss, U Jain, F Macciardi, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147 …, 2008 | 68 | 2008 |
Cellular models to study bipolar disorder: a systematic review B Viswanath, SP Jose, A Squassina, J Thirthalli, M Purushottam, ... Journal of affective disorders 184, 36-50, 2015 | 66 | 2015 |
New insights on the genetic etiology of Alzheimer’s and related dementia C Bellenguez, F Küçükali, I Jansen, V Andrade, S Moreno-Grau, N Amin, ... MedRxiv, 2020.10. 01.20200659, 2020 | 65 | 2020 |