The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR RM Chin, X Fu, MY Pai, L Vergnes, H Hwang, G Deng, S Diep, ... Nature 510 (7505), 397-401, 2014 | 639 | 2014 |
An antidepressant that extends lifespan in adult Caenorhabditis elegans M Petrascheck, X Ye, LB Buck Nature 450 (7169), 553-556, 2007 | 333 | 2007 |
Measuring Caenorhabditis elegans life span in 96 well microtiter plates GM Solis, M Petrascheck JoVE (Journal of Visualized Experiments), e2496, 2011 | 202 | 2011 |
The DrugAge database of aging‐related drugs D Barardo, D Thornton, H Thoppil, M Walsh, S Sharifi, S Ferreira, A Anžič, ... Aging cell 16 (3), 594-597, 2017 | 161 | 2017 |
Proton pump inhibitors accelerate endothelial senescence G Yepuri, R Sukhovershin, TZ Nazari-Shafti, M Petrascheck, YT Ghebre, ... Circulation research 118 (12), e36-e42, 2016 | 153 | 2016 |
A pharmacological network for lifespan extension in Caenorhabditis elegans X Ye, JM Linton, NJ Schork, LB Buck, M Petrascheck Aging cell 13 (2), 206-215, 2014 | 151 | 2014 |
The mitochondrial ATP synthase is a shared drug target for aging and dementia J Goldberg, A Currais, M Prior, W Fischer, C Chiruta, E Ratliff, ... Aging cell 17 (2), e12715, 2018 | 138 | 2018 |
DNA looping induced by a transcriptional enhancer in vivo M Petrascheck, D Escher, T Mahmoudi, CP Verrijzer, W Schaffner, ... Nucleic acids research 33 (12), 3743-3750, 2005 | 121 | 2005 |
Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality S Rangaraju, GM Solis, RC Thompson, RL Gomez-Amaro, L Kurian, ... Elife 4, e08833, 2015 | 110 | 2015 |
Metabolic drift in the aging brain J Ivanisevic, KL Stauch, M Petrascheck, HP Benton, AA Epstein, M Fang, ... Aging (Albany NY) 8 (5), 1000, 2016 | 106 | 2016 |
Elevating acetyl-CoA levels reduces aspects of brain aging A Currais, L Huang, J Goldberg, M Petrascheck, G Ates, A Pinto-Duarte, ... Elife 8, e47866, 2019 | 102 | 2019 |
Measuring Food Intake and Nutrient Absorption in Caenorhabditis elegans RL Gomez-Amaro, ER Valentine, M Carretero, SE LeBoeuf, S Rangaraju, ... Genetics 200 (2), 443-454, 2015 | 93 | 2015 |
A High‐Throughput Screen for Chemicals that Increase the Lifespan of Caenorhabditis elegans M Petrascheck, X Ye, LB Buck Annals of the New York Academy of Sciences 1170 (1), 698-701, 2009 | 73 | 2009 |
Organ polarity in Arabidopsis. NOZZLE physically interacts with members of the YABBY family P Sieber, M Petrascheck, A Barberis, K Schneitz Plant physiology 135 (4), 2172-2185, 2004 | 68 | 2004 |
C. elegans S6K mutants require a creatine-kinase-like effector for lifespan extension PR McQuary, CY Liao, JT Chang, C Kumsta, X She, A Davis, CC Chu, ... Cell reports 14 (9), 2059-2067, 2016 | 59 | 2016 |
Rapamycin‐mediated mouse lifespan extension: late‐life dosage regimes with sex‐specific effects R Strong, RA Miller, M Bogue, E Fernandez, MA Javors, S Libert, ... Aging Cell 19 (11), e13269, 2020 | 57 | 2020 |
C. elegans as model for drug discovery M Carretero, GM Solis, M Petrascheck Curr Top Med Chem 17 (18), 2067-76, 2017 | 55 | 2017 |
Translation attenuation by minocycline enhances longevity and proteostasis in old post-stress-responsive organisms GM Solis, R Kardakaris, ER Valentine, L Bar-Peled, AL Chen, MM Blewett, ... Elife 7, e40314, 2018 | 53 | 2018 |
Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan AL Chen, KM Lum, P Lara-Gonzalez, D Ogasawara, AB Cognetta III, A To, ... Nature chemical biology 15 (5), 453-462, 2019 | 44 | 2019 |
Geroneuroprotectors: effective geroprotectors for the brain D Schubert, A Currais, J Goldberg, K Finley, M Petrascheck, P Maher Trends in pharmacological sciences 39 (12), 1004-1007, 2018 | 42 | 2018 |