CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants LM Hesse, K Venkatakrishnan, C MH, von Moltke LL, D SX, S RI, ... Drug Metab Dispos 28 (10), 1176-1183, 2000 | 470* | 2000 |
Nonsteroidal anti-inflammatory drugs in cats: a review BDX Lascelles, MH Court, EM Hardie, SA Robertson Veterinary anaesthesia and analgesia 34 (4), 228-250, 2007 | 262 | 2007 |
Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes MH Hesse, L. M., He, P., Krishnaswamy, S., Hao, Q., Hogan, K., von Moltke, L ... Pharmacogenetics and genomics 14 (4), 225-238, 2004 | 238 | 2004 |
Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor LP Volak, S Ghirmai, JR Cashman Drug metabolism and disposition 36 (8), 1594-1605, 2008 | 235 | 2008 |
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing RS Gammal, MH Court, CE Haidar, OF Iwuchukwu, AH Gaur, M Alvarellos, ... Clinical Pharmacology & Therapeutics 99 (4), 363-369, 2016 | 187 | 2016 |
Evaluation of 3′-azido-3′-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and … S Krishnaswamy, Q Hao, SX Duan, CJ Patten, LL Von Moltke, ... Drug Metabolism and Disposition 31 (9), 1125-1133, 2003 | 186 | 2003 |
CYP2B6, CYP2A6 and UGT2B7 genetic polymorphisms are predictors of efavirenz mid-dose concentration in HIV-infected patients A Kwara, M Lartey, KWC Sagoe, E Kenu Aids 23 (16), 2101-2106, 2009 | 172 | 2009 |
Court, MH, & Dixon, R.(1987). Investigation into the use of narcotic antagonists in the treatment of a stereotypic behavior pattern (crib-biting) in the horse NH Dodman, L Shuster American Journal of Veterinary Research 48 (2), 311-318, 1987 | 171* | 1987 |
Comparison between cytochrome P450 (CYP) content and relative activity approaches to scaling from cDNA-expressed CYPs to human liver microsomes: ratios of accessory proteins as … K Venkatakrishnan, LL von Moltke, JS Harmatz, CL Crespi, DJ Greenblatt Drug metabolism and disposition 28 (12), 1493-1504, 2000 | 170 | 2000 |
Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues MH Court, X Zhang, X Ding, KK Yee, LM Hesse, M Finel Xenobiotica 42 (3), 266-277, 2012 | 163 | 2012 |
Genotype‐phenotype associations of cytochrome P450 3A4 and 3A5 polymorphism with midazolam clearance in vivo P He, MH Court, DJ Greenblatt, LL Von Moltke Clinical Pharmacology & Therapeutics 77 (5), 373-387, 2005 | 163 | 2005 |
Validation of serotonin (5-hydroxtryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6 S Krishnaswamy, SX Duan, LL Von Moltke, DJ Greenblatt Drug Metabolism and Disposition 31 (1), 133-139, 2003 | 152 | 2003 |
Court, MH, Yan, B., & Akhlaghi, F.(2011). Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus M Dostalek British Journal of Pharmacology 163 (5), 937-947, 2011 | 147* | 2011 |
CYP2B6 (c.516G→T) and CYP2A6 (*9B and/or *17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV‐infected patients A Kwara, M Lartey, KW Sagoe, NL Rzek, MH Court British journal of clinical pharmacology 67 (4), 427-436, 2009 | 146 | 2009 |
Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes MH Court, SX Duan, LM Hesse, K Venkatakrishnan, DJ Greenblatt The Journal of the American Society of Anesthesiologists 94 (1), 110-119, 2001 | 146 | 2001 |
Molecular basis for deficient acetaminophen glucuronidation in cats: An interspecies comparison of enzyme kinetics in liver microsomes MH Court, DJ Greenblatt Biochemical pharmacology 53 (7), 1041-1047, 1997 | 146 | 1997 |
UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: II. Functional impact of the three most common nonsynonymous UGT1A6 polymorphisms (S7A, T181A, and R184S) S Krishnaswamy, Q Hao, A Al-Rohaimi, LM Hesse, LL von Moltke, ... Journal of Pharmacology and Experimental Therapeutics 313 (3), 1340-1346, 2005 | 141 | 2005 |
COURT MH, DIAAN SX, HARMATZ JS, SHADER RI (1995) Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective … V MOLTKE, DJ Greenblatt J Clin Psychopharmacol 15, 125-131, 1995 | 141* | 1995 |
Midazolam and triazolam biotransformation in mouse and human liver microsomes: relative contribution of CYP3A and CYP2C isoforms MD Perloff, LL von Moltke, T Kotegawa, RI Shader, DJ Greenblatt Journal of Pharmacology and Experimental Therapeutics 292 (2), 618-628, 2000 | 139 | 2000 |
Isoform‐selective probe substrates for in vitro studies of human UDP‐glucuronosyltransferases MH Court Methods in enzymology 400, 104-116, 2005 | 138 | 2005 |