Tuning the cis/trans Conformer Ratio of Xaa–Pro Amide Bonds by Intramolecular Hydrogen Bonds: The Effect on PPII Helix Stability M Kuemin, YA Nagel, S Schweizer, FW Monnard, C Ochsenfeld, ... Angewandte Chemie 122 (36), 6468-6471, 2010 | 121 | 2010 |
Effect of preorganized charge‐display on the cell‐penetrating properties of cationic peptides YA Nagel, PS Raschle, H Wennemers Angewandte Chemie 129 (1), 128-132, 2017 | 106 | 2017 |
Asymmetric conjugate addition of ketones to β‐nitrostyrenes by means of 1, 2‐amino‐alcohol‐derived prolinamides as bifunctional catalysts D Almaşi, DA Alonso, E Gómez‐Bengoa, Y Nagel, C Najera European journal of organic chemistry 2007 (14), 2328-2343, 2007 | 42 | 2007 |
Impact of the Proline Residue on Ligand Binding of Neurotensin Receptor 2 (NTS2)‐Selective Peptide–Peptoid Hybrids C Held, H Hübner, R Kling, YA Nagel, H Wennemers, P Gmeiner ChemMedChem 8 (5), 772-778, 2013 | 26 | 2013 |
Functionalizable oligoprolines as molecular scaffolds YA Nagel, M Kuemin, H Wennemers Chimia 65 (4), 264-264, 2011 | 26 | 2011 |
Stabilized polypeptides and uses thereof GL Verdine, YA Nagel US Patent App. 15/026,473, 2016 | 19 | 2016 |
Reaktionen von Tetrachloroaurat mit verschiedenen Aminen Y Nagel, W Beck Zeitschrift für anorganische und allgemeine Chemie 529 (10), 57-60, 1985 | 19 | 1985 |
Stabilized polypeptide insulin receptor modulators GL Verdine, G Hilinski, RY Liang, YA Nagel, M Zhou US Patent 10,227,390, 2019 | 18 | 2019 |
Metallkomplexe mit biologisch wichtigen Liganden, XLI [1]. Platin (II)-und Cobalt (III)-Komplexe von Monosaccharid-Derivaten mit Metall-Schwefel-und Metall-Kohlenstoff … Y Nagel, W Beck Zeitschrift für Naturforschung B 40 (9), 1181-1187, 1985 | 18 | 1985 |
Effect of γ-substituted proline derivatives on the performance of the peptidic catalyst H-dPro-pro-Glu-NH2 T Schnitzer, H Wennemers Synthesis 50 (22), 4377-4382, 2018 | 16 | 2018 |
Discovery of novel allosteric EGFR L858R inhibitors for the treatment of non-small-cell lung cancer as a single agent or in combination with osimertinib U Obst-Sander, A Ricci, B Kuhn, T Friess, P Koldewey, A Kuglstatter, ... Journal of medicinal chemistry 65 (19), 13052-13073, 2022 | 13 | 2022 |
Metallkomplexe mit biologisch wichtigen Liganden, XLIII Metallkomplexe mit ungeschützten acyclischen Monosaccharid-Derivaten (Amin-, Oxim-, Schiffbase-, Thiazolidin-und 1, 3 … Y Nagel, W Beck Zeitschrift für Naturforschung B 41 (11), 1447-1454, 1986 | 13 | 1986 |
Proteolysis-targeting chimeras enhance T cell bispecific antibody-driven T cell activation and effector function through increased MHC class I antigen presentation in cancer cells V Massafra, S Tundo, A Dietzig, A Ducret, C Jost, C Klein, RE Kontermann, ... The Journal of Immunology 207 (2), 493-504, 2021 | 11 | 2021 |
Bifunctional inhibitors with egfr having a e3 ubiquitin ligase moiety G Jaeschke, B Kuhn, A Ricci, D Rueher, S Steiner, YA Nagel, M Duplessis, ... US Patent App. 16/903,237, 2020 | 6 | 2020 |
From Degraders to Molecular Glues: New Ways of Breaking Down Disease‐Associated Proteins YA Nagel, A Britschgi, A Ricci Successful Drug Discovery, 47-85, 2021 | 5 | 2021 |
Compounds M Duplessis, A Goergler, G Jaeschke, B Kocer, B Kuhn, K Lazarski, ... Publication number: 20210079005, March 18, 2021 | 4 | 2021 |
Bifunctional molecules that degrade egfr M Duplessis, G Jaeschke, B Kuhn, K Lazarski, Y Liang, YA Nagel, A Ricci, ... US Patent App. 16/984,987, 2020 | 4 | 2020 |
Paradigms for the development of transformative medicines—lessons from the EGFR story W Pao, YA Nagel Annals of Oncology 33 (5), 556-560, 2022 | 3 | 2022 |
Cell-penetrating peptides (CPPs) based on an oligoproline scaffold-design, synthesis and biological evaluation and conformational analysis of functionalized proline derivatives YA Nagel University_of_Basel, 2014 | 2 | 2014 |
Metal Complexes with Biologically Important Ligands. Part 43. Metal Complexes with Unprotected Acyclic Derivatives of Monosaccharides (Amine, Oxime, Schiff Base, Thiazolidine … Y Nagel, W Beck ChemInform 18 (13), no-no, 1987 | 2 | 1987 |