| Synaptic, transcriptional and chromatin genes disrupted in autism S De Rubeis, X He, AP Goldberg, CS Poultney, K Samocha, AE Cicek, ... Nature 515 (7526), 209-215, 2014 | 2807 | 2014 |
| Insights into autism spectrum disorder genomic architecture and biology from 71 risk loci SJ Sanders, X He, AJ Willsey, AG Ercan-Sencicek, KE Samocha, ... Neuron 87 (6), 1215-1233, 2015 | 1508 | 2015 |
| Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism AJ Willsey, SJ Sanders, M Li, S Dong, AT Tebbenkamp, RA Muhle, ... Cell 155 (5), 997-1007, 2013 | 979 | 2013 |
| Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics J Morrison, N Knoblauch, JH Marcus, M Stephens, X He Nature Genetics, 1-7, 2020 | 400 | 2020 |
| Integrated Model of De Novo and Inherited Genetic Variants Yields Greater Power to Identify Risk Genes X He, SJ Sanders, L Liu, S De Rubeis, ET Lim, JS Sutcliffe, ... PLoS genetics 9 (8), e1003671, 2013 | 298 | 2013 |
| An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder DM Werling, H Brand, JY An, MR Stone, L Zhu, JT Glessner, RL Collins, ... Nat Genet 50 (5), 727-736, 2018 | 273 | 2018 |
| Sherlock: Detecting Gene-Disease Associations by Matching Patterns of Expression QTL and GWAS X He, CK Fuller, Y Song, Q Meng, B Zhang, X Yang, H Li The American Journal of Human Genetics 92 (5), 667-680, 2013 | 265 | 2013 |
| Genes with de novo mutations are shared by four neuropsychiatric disorders discovered from NPdenovo database J Li, T Cai, Y Jiang, H Chen, X He, C Chen, X Li, Q Shao, X Ran, Z Li, ... Molecular psychiatry, 2015 | 228 | 2015 |
| Thermodynamics-based models of transcriptional regulation by enhancers: the roles of synergistic activation, cooperative binding and short-range repression X He, MAH Samee, C Blatti, S Sinha PLoS computational biology 6 (9), e1000935, 2010 | 211 | 2010 |
| DAWN: a framework to identify autism genes and subnetworks using gene expression and genetics L Liu, J Lei, SJ Sanders, AJ Willsey, Y Kou, AE Cicek, L Klei, C Lu, X He, ... Mol Autism 5, 22, 2014 | 146 | 2014 |
| Genetic analyses support the contribution of mRNA N 6-methyladenosine (m 6 A) modification to human disease heritability Z Zhang, K Luo, Z Zou, M Qiu, J Tian, L Sieh, H Shi, Y Zou, G Wang, ... Nature Genetics 52 (9), 939-949, 2020 | 140 | 2020 |
| Synbiotic-driven improvement of metabolic disturbances is associated with changes in the gut microbiome in diet-induced obese mice X Ke, A Walker, SB Haange, I Lagkouvardos, Y Liu, P Schmitt-Kopplin, ... Molecular metabolism, 2019 | 129 | 2019 |
| Targeted sequencing and functional analysis reveal brain-size-related genes and their networks in autism spectrum disorders J Li, L Wang, H Guo, L Shi, K Zhang, M Tang, S Hu, S Dong, Y Liu, ... Molecular psychiatry 22 (9), 1282-1290, 2017 | 98 | 2017 |
| Evolution of regulatory sequences in 12 Drosophila species J Kim, X He, S Sinha PLoS genetics 5 (1), e1000330, 2009 | 98 | 2009 |
| Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders HT Nguyen, J Bryois, A Kim, A Dobbyn, LM Huckins, ... Genome medicine 9 (1), 114, 2017 | 92 | 2017 |
| Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants S Zhang, H Zhang, Y Zhou, M Qiao, S Zhao, A Kozlova, J Shi, AR Sanders, ... Science 369 (6503), 561-565, 2020 | 91 | 2020 |
| PAK2 haploinsufficiency results in synaptic cytoskeleton impairment and autism-related behavior Y Wang, C Zeng, J Li, Z Zhou, X Ju, S Xia, Y Li, A Liu, H Teng, K Zhang, ... Cell reports 24 (8), 2029-2041, 2018 | 89 | 2018 |
| Large-scale analysis of transcriptional cis-regulatory modules reveals both common features and distinct subclasses L Li, Q Zhu, X He, S Sinha, MS Halfon Genome Biol 8 (6), R101, 2007 | 85 | 2007 |
| Identifying conserved gene clusters in the presence of homology families X He, MH Goldwasser Journal of computational biology 12 (6), 638-656, 2005 | 78 | 2005 |
| Evolutionary origins of transcription factor binding site clusters X He, TSPC Duque, S Sinha Molecular biology and evolution 29 (3), 1059-1070, 2012 | 76 | 2012 |
