Biological stress response terminology: integrating the concepts of adaptive response and preconditioning stress within a hormetic dose–response framework EJ Calabrese, KA Bachmann, AJ Bailer, PM Bolger, J Borak, L Cai, ... Toxicology and applied pharmacology 222 (1), 122-128, 2007 | 789 | 2007 |
Human pregnane X receptor antagonists and agonists define molecular requirements for different binding sites S Ekins, C Chang, S Mani, MD Krasowski, EJ Reschly, M Iyer, ... Molecular pharmacology 72 (3), 592-603, 2007 | 177 | 2007 |
Pharmacology: principles and practice M Hacker, WS Messer, KA Bachmann Academic Press, 2009 | 171 | 2009 |
Predicting inhibitory drug—drug interactions and evaluating drug interaction reports using inhibition constants KA Bachmann, JD Lewis Annals of Pharmacotherapy 39 (6), 1064-1072, 2005 | 131 | 2005 |
Drug–drug interactions with an emphasis on drug metabolism and transport K Bachmann Pharmacology, 303-325, 2009 | 128 | 2009 |
Cyclooxygenase‐2 inhibition by rofecoxib reverses naturally occurring fever in humans JI Schwartz, CC Chan, S Mukhopadhyay, KJ McBride, TM Jones, ... Clinical Pharmacology & Therapeutics 65 (6), 653-660, 1999 | 128 | 1999 |
Dispositional and pharmacodynamic characteristics of brodifacoum in warfarin-sensitive rats KA Bachmann, TJ Sullivan Pharmacology 27 (5), 281-288, 1983 | 124 | 1983 |
Scaling basic toxicokinetic parameters from rat to man. K Bachmann, D Pardoe, D White Environmental health perspectives 104 (4), 400-407, 1996 | 116 | 1996 |
Impact of ciprofloxacin on theophylline clearance and steady-state concentrations in serum J Schwartz, L Jauregui, J Lettieri, K Bachmann Antimicrobial agents and chemotherapy 32 (1), 75-77, 1988 | 104 | 1988 |
PXR and the regulation of apoA1 and HDL-cholesterol in rodents K Bachmann, H Patel, Z Batayneh, J Slama, D White, J Posey, S Ekins, ... Pharmacological Research 50 (3), 237-246, 2004 | 92 | 2004 |
A comprehensive in vitro and in silico analysis of antibiotics that activate pregnane X receptor and induce CYP3A4 in liver and intestine K Yasuda, A Ranade, R Venkataramanan, S Strom, J Chupka, S Ekins, ... Drug metabolism and disposition 36 (8), 1689-1697, 2008 | 91 | 2008 |
Computational discovery of novel low micromolar human pregnane X receptor antagonists S Ekins, V Kholodovych, N Ai, M Sinz, J Gal, L Gera, WJ Welsh, ... Molecular pharmacology 74 (3), 662-672, 2008 | 88 | 2008 |
The use of in vitro methods to predict in vivo pharmacokinetics and drug interactions KA Bachmann, R Ghosh Current drug metabolism 2 (3), 299-314, 2001 | 80 | 2001 |
An investigation of the relationship between estrogen, estrogen metabolites and blood cholesterol levels in ovariectomized rats D Liu, KA Bachmann Journal of Pharmacology and Experimental Therapeutics 286 (1), 561-568, 1998 | 72 | 1998 |
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo KA Bachmann, L Jauregui Xenobiotica 23 (3), 307-315, 1993 | 72 | 1993 |
Inhibition constants, inhibitor concentrations and the prediction of inhibitory drug drug interactions: pitfalls, progress and promise KA Bachmann Current drug metabolism 7 (1), 1-14, 2006 | 67 | 2006 |
Inappropriate prescriptions for the aging population of the United States: an analysis of the National Ambulatory Medical Care Survey, 1997 B Huang, KA Bachmann, X He, R Chen, JS McAllister, T Wang Pharmacoepidemiology and drug safety 11 (2), 127-134, 2002 | 61 | 2002 |
Drug metabolism K Bachmann Pharmacology, 131-173, 2009 | 58 | 2009 |
The influence of anesthetic agents on rat hepatic cytochromes P450 in vivo JM Loch, J Potter, KA Bachmann Pharmacology 50 (3), 146-153, 1995 | 58 | 1995 |
Estimating xenobiotic half-lives in humans from rat data: influence of log P. JG Sarver, D White, P Erhardt, K Bachmann Environmental health perspectives 105 (11), 1204-1209, 1997 | 53 | 1997 |