YAP/TAZ Inhibition Induces Metabolic and Signaling Rewiring Resulting in Targetable Vulnerabilities in NF2-Deficient Tumor Cells SM White, ML Avantaggiati, I Nemazanyy, C Di Poto, Y Yang, M Pende, ... Developmental cell 49 (3), 425-443, 2019 | 95 | 2019 |
Why senescent cells are resistant to apoptosis: an insight for senolytic development L Hu, H Li, M Zi, W Li, J Liu, Y Yang, D Zhou, QP Kong, Y Zhang, Y He Frontiers in Cell and Developmental Biology 10, 822816, 2022 | 84 | 2022 |
Discovery of IAP-recruiting BCL-XL PROTACs as potent degraders across multiple cancer cell lines X Zhang, Y He, P Zhang, V Budamagunnta, D Lv, D Thummuri, Y Yang, ... Eur J Med Chem 1 (199), 1-28, 2020 | 48 | 2020 |
Senescence-associated hyper-activation to inflammatory stimuli in vitro V Budamagunta, S Manohar-Sindhu, Y Yang, Y He, DO Traktuev, ... Aging (Albany NY) 13 (15), 19088, 2021 | 37 | 2021 |
Effect of peripheral cellular senescence on brain aging and cognitive decline V Budamagunta, A Kumar, A Rani, L Bean, S Manohar‐Sindhu, Y Yang, ... Aging Cell 22 (5), e13817, 2023 | 25 | 2023 |
Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice S Khan, P Kellish, N Connis, D Thummuri, J Wiegand, P Zhang, X Zhang, ... Cell Death Discovery 9 (1), 1, 2023 | 17 | 2023 |
The curcumin analog EF24 is highly active against chemotherapy-resistant melanoma cells Y He, W Li, J Zhang, Y Yang, Y Qian, D Zhou Current Cancer Drug Targets 21 (7), 608-618, 2021 | 8 | 2021 |
Senolytic treatment alleviates doxorubicin‐induced chemobrain V Budamagunta, A Kumar, A Rani, S Manohar Sindhu, Y Yang, D Zhou, ... Aging cell 23 (2), e14037, 2024 | 4 | 2024 |
Revolutionizing diabetic foot ulcer care: the senotherapeutic approach G Zhang, PN Samarawickrama, L Gui, Y Ma, M Cao, H Zhu, W Li, H Yang, ... Aging and Disease, 2024 | 2 | 2024 |
Abstract B009: A liver-tropic BCL-xL PROTAC effectively clears senescent hepatocytes and prevents NASH-driven HCC in mice Y Yang, N Jn-Simon, W Hu, P Zhang, G Zheng, L Pi, Y He, D Zhou Cancer Research 83 (2_Supplement_1), B009-B009, 2023 | 1 | 2023 |
Characterizing cellular senescence response to senolytic compounds using cell culture media analysis E Wang, S Kurzyniec, E Hain, Y Okamura, Y Yang, D Lv Cancer Research 83 (7_Supplement), 4792-4792, 2023 | | 2023 |
Targeting endogenous and therapy-induced dependence on BCL-XL in high grade serous ovarian carcinoma L Johnson, X Qin, C Fraser, E Stover, Y Yang, D Zhou, B Rueda, ... Cancer Research 83 (7_Supplement), 6161-6161, 2023 | | 2023 |
Hippo-YAP Inhibitors Synergize with MEK and ERK Inhibitors in NF2 Deficient Schwannoma Cell Lines CYJF Yang Yang, Shannon M. White, Tracy T. Tang, Leonard Post 2019 NF Conference, 61, 2019 | | 2019 |
1. Novel Aspect EH Wang, S Kurzyniec, Y Okamura, Y Yang, D Lyu | | |