Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters P Cimermancic, MH Medema, J Claesen, K Kurita, LCW Brown, ... Cell 158 (2), 412-421, 2014 | 958 | 2014 |
Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 864 | 2015 |
Synthetic biology to access and expand nature's chemical diversity MJ Smanski, H Zhou, J Claesen, B Shen, MA Fischbach, CA Voigt Nature Reviews Microbiology 14 (3), 135-149, 2016 | 532 | 2016 |
Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights Y Goto, B Li, J Claesen, Y Shi, MJ Bibb, WA van der Donk PLoS biology 8 (3), e1000339, 2010 | 270 | 2010 |
Synthetic microbes as drug delivery systems J Claesen, MA Fischbach ACS synthetic biology 4 (4), 358-364, 2015 | 174 | 2015 |
Genome mining and genetic analysis of cypemycin biosynthesis reveal an unusual class of posttranslationally modified peptides J Claesen, M Bibb Proceedings of the National Academy of Sciences 107 (37), 16297-16302, 2010 | 169 | 2010 |
Contextual control of skin immunity and inflammation by Corynebacterium VK Ridaura, N Bouladoux, J Claesen, YE Chen, AL Byrd, ... Journal of Experimental Medicine 215 (3), 785-799, 2018 | 165 | 2018 |
A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles J Claesen, JB Spagnolo, SF Ramos, KL Kurita, AL Byrd, AA Aksenov, ... Science translational medicine 12 (570), eaay5445, 2020 | 113* | 2020 |
Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut A Bell, J Brunt, E Crost, L Vaux, R Nepravishta, CD Owen, D Latousakis, ... Nature microbiology 4 (12), 2393-2404, 2019 | 112 | 2019 |
Propionibacterium-Produced Coproporphyrin III Induces Staphylococcus aureus Aggregation and Biofilm Formation MS Wollenberg, J Claesen, IF Escapa, KL Aldridge, MA Fischbach, ... MBio 5 (4), 10.1128/mbio. 01286-14, 2014 | 107 | 2014 |
Biosynthesis and regulation of grisemycin, a new member of the linaridin family of ribosomally synthesized peptides produced by Streptomyces griseus IFO 13350 J Claesen, MJ Bibb Journal of bacteriology 193 (10), 2510-2516, 2011 | 80 | 2011 |
A Streptomyces coelicolor host for the heterologous expression of Type III polyketide synthase genes A Thanapipatsiri, J Claesen, JP Gomez-Escribano, M Bibb, ... Microbial Cell Factories 14, 1-11, 2015 | 47 | 2015 |
Identification of essential genes for Escherichia coli aryl polyene biosynthesis and function in biofilm formation I Johnston, LJ Osborn, RL Markley, EA McManus, A Kadam, KB Schultz, ... npj Biofilms and Microbiomes 7, 56, 2021 | 39 | 2021 |
Disruption of the gut microbiota confers cisplatin resistance in epithelial ovarian cancer LM Chambers, EL Esakov Rhoades, R Bharti, C Braley, S Tewari, ... Cancer research 82 (24), 4654-4669, 2022 | 37* | 2022 |
Gut symbionts Lactobacillus reuteri R2lc and 2010 encode a polyketide synthase cluster that activates the mammalian aryl hydrocarbon receptor M Özçam, R Tocmo, JH Oh, A Afrazi, JD Mezrich, S Roos, J Claesen, ... Applied and Environmental Microbiology 85 (10), e01661-18, 2019 | 30 | 2019 |
Microbial flavonoid metabolism: a cardiometabolic disease perspective LJ Osborn, J Claesen, JM Brown Annual Review of Nutrition 41, 433-454, 2021 | 20 | 2021 |
A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis LJ Osborn, K Schultz, W Massey, B DeLucia, I Choucair, V Varadharajan, ... Proceedings of the National Academy of Sciences 119 (48), e2202934119, 2022 | 14 | 2022 |
A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation M Özçam, JH Oh, R Tocmo, D Acharya, S Zhang, TJ Astmann, M Heggen, ... Cell Host & Microbe 30 (6), 824-835. e6, 2022 | 12 | 2022 |
A surgical method for continuous intraportal infusion of gut microbial metabolites in mice D Orabi, LJ Osborn, K Fung, W Massey, AJ Horak III, F Aucejo, I Choucair, ... JCI insight 6 (9), 2021 | 9* | 2021 |
Topical antiseptics and the skin microbiota J Claesen Journal Of Investigative Dermatology 138 (10), 2106-2107, 2018 | 9 | 2018 |