Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia L Noetzli, RW Lo, AB Lee-Sherick, M Callaghan, P Noris, A Savoia, ... Nature genetics 47 (5), 535-538, 2015 | 353 | 2015 |
Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease WHA Kahr, FG Pluthero, A Elkadri, N Warner, M Drobac, CH Chen, RW Lo, ... Nature communications 8 (1), 14816, 2017 | 208 | 2017 |
Abnormal megakaryocyte development and platelet function in Nbeal2−/− mice WHA Kahr, RW Lo, L Li, FG Pluthero, H Christensen, R Ni, N Vaezzadeh, ... Blood, The Journal of the American Society of Hematology 122 (19), 3349-3358, 2013 | 133 | 2013 |
Intracellular trafficking, localization, and mobilization of platelet-borne thiol isomerases M Crescente, FG Pluthero, L Li, RW Lo, TG Walsh, MP Schenk, ... Arteriosclerosis, thrombosis, and vascular biology 36 (6), 1164-1173, 2016 | 71 | 2016 |
FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets AJ Begonja, FG Pluthero, W Suphamungmee, S Giannini, H Christensen, ... Blood, The Journal of the American Society of Hematology 126 (1), 80-88, 2015 | 66 | 2015 |
α-granule biogenesis: from disease to discovery CH Chen, RW Lo, D Urban, FG Pluthero, WHA Kahr Platelets 28 (2), 147-154, 2017 | 61 | 2017 |
NBEAL2 (Neurobeachin-Like 2) is required for retention of cargo proteins by α-granules during their production by megakaryocytes RW Lo, L Li, R Leung, FG Pluthero, WHA Kahr Arteriosclerosis, Thrombosis, and Vascular Biology 38 (10), 2435-2447, 2018 | 47 | 2018 |
The endoplasmic reticulum protein SEC22B interacts with NBEAL2 and is required for megakaryocyte α-granule biogenesis RW Lo, L Li, FG Pluthero, R Leung, K Eto, WHA Kahr Blood, The Journal of the American Society of Hematology 136 (6), 715-725, 2020 | 20 | 2020 |
Investigating the functional roles of NBEAL2 in megakaryocytes and platelets RWC Lo University of Toronto (Canada), 2019 | | 2019 |
NBEAL2 is required for retention of endocytosed and megakaryocyte synthesized alpha-granule cargo proteins RW Lo, L Li, R Leung, FG Pluthero, WH Kahr MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |
Dynamin 2 (DNM2) and PACSIN2 Regulate Megakaryocyte Demarcation Membrane System Formation and Platelet Production in Concert S Giannini, M Bender, FG Pluthero, H Christensen, R Leung, RW Lo, ... Blood, The Journal of the American Society of Hematology 126 (23), 419-419, 2015 | | 2015 |
Functional analysis of NBEAL2 in human megakaryocytes via colocalization with subcellular compartments RW Lo, FG Pluthero, L Li, WH Kahr JOURNAL OF THROMBOSIS AND HAEMOSTASIS 13, 889-889, 2015 | | 2015 |
Biogenesis, subcellular localization and mobilization of two abundant platelet thiol isomerases M Crescente, FG Pluthero, MP Schenk, L Li, RW Lo, MS Ali, S Vaiyapuri, ... Journal Of Thrombosis And Haemostasis 13, 445-445, 2015 | | 2015 |
Receptor-mediated endocytosis is required for normal megakaryocyte demarcation membrane system formation and platelet production S Giannini, FG Pluthero, H Christensen, R Leung, RW Lo, J Kormann, ... J. Thromb. Haemost. 13, 185-186, 2015 | | 2015 |
Abnormal megakaryocyte development and platelet function in WHA Kahr, RW Lo, L Li, FG Pluthero, H Christensen, R Ni, N Vaezzadeh, ... | | 2013 |