GPCR kinase knockout cells reveal the impact of individual GRKs on arrestin binding and GPCR regulation J Drube, RS Haider, ESF Matthees, M Reichel, J Zeiner, S Fritzwanker, ... Nature communications 13 (1), 540, 2022 | 68 | 2022 |
Differential regulation of GPCRs—are GRK expression levels the key? ESF Matthees, RS Haider, C Hoffmann, J Drube Frontiers in Cell and Developmental Biology 9, 687489, 2021 | 42 | 2021 |
β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells RS Haider, ESF Matthees, J Drube, M Reichel, U Zabel, A Inoue, ... Nature Communications 13 (1), 5638, 2022 | 32 | 2022 |
Circulating bile acids in liver failure activate TGR5 and induce monocyte dysfunction J Leonhardt, RS Haider, C Sponholz, S Leonhardt, J Drube, K Spengler, ... Cellular and molecular gastroenterology and hepatology 12 (1), 25-40, 2021 | 31 | 2021 |
To sense or not to sense—new insights from GPCR-based and arrestin-based biosensors RS Haider, A Godbole, C Hoffmann Current Opinion in Cell Biology 57, 16-24, 2019 | 22 | 2019 |
Arrestin-1 engineering facilitates complex stabilization with native rhodopsin RS Haider, F Wilhelm, A Rizk, E Mutt, X Deupi, C Peterhans, J Mühle, ... Scientific reports 9 (1), 439, 2019 | 9 | 2019 |
Conformational flexibility of β‐arrestins–How these scaffolding proteins guide and transform the functionality of GPCRs RS Haider, M Reichel, ESF Matthees, C Hoffmann BioEssays 45 (8), 2300053, 2023 | 6 | 2023 |
Phosphorylation of the D1 Dopamine Receptor by G Protein‐Coupled Receptor Kinases: phosphorylation site identification and linkage to functional effects A Moritz, M Rankin, L Inbody, R Free, R Haider, J Drube, C Hoffmann, ... The FASEB Journal 35, 2021 | 3 | 2021 |
β-arrestin–based biosensors: Tools to explore structural determinants of metabolic functions? ESF Matthees, RS Haider, C Hoffmann Current Opinion in Endocrine and Metabolic Research 16, 66-74, 2021 | 3 | 2021 |
Arrestin‐centred interactions at the membrane and their conformational determinants O Underwood, RS Haider, J Sanchez, M Canals British Journal of Pharmacology, 2024 | 2 | 2024 |
G protein‐coupled receptor kinase 2 can enhance β‐arrestin recruitment to the D2 dopamine receptor in the absence of receptor phosphorylation M Sanchez Soto, C Dasaro, K Schardien, L Inbody, R Free, J Drube, ... The FASEB Journal 35, 2021 | 1 | 2021 |
Regulation of Dopamine Receptor Subtypes by G Protein-Coupled Receptor Kinase Isoforms AE Moritz, NS Madaras, KK Snyder, NM Boldizsar, R Haider, J Drube, ... Journal of Pharmacology and Experimental Therapeutics 389 (S3), 2024 | | 2024 |
S1PR3 agonism and S1P lyase inhibition rescue mice in the severe state of experimental sepsis AC Ziegler, RS Haider, C Hoffmann, MH Gräler Biomedicine & Pharmacotherapy 174, 116575, 2024 | | 2024 |
Microbially conjugated bile salts found in human bile activate the bile salt receptors TGR5 and FXR Ü Ay, M Leníček, RS Haider, A Classen, H van Eijk, KVK Koelfat, ... Hepatology communications 8 (4), e0383, 2024 | | 2024 |
G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of … M Sánchez-Soto, NM Boldizsar, KA Schardien, NS Madaras, BKA Willette, ... Biomolecules 13 (10), 1552, 2023 | | 2023 |
The novel class of microbially conjugated bile salts activate the main host bile salt receptors FXR and TGR5 Ü Ay, M Lenicek, R Haider, A Classen, H van Eijk, C Hoffmann, C Bolm, ... Journal of Hepatology 78, S350-S351, 2023 | | 2023 |
Delineation of the G Protein-Coupled Receptor Kinase Phosphorylation Sites Within the D1 Dopamine Receptor and Their Role in Regulating Receptor Function NS Madaras, ML Rankin, RB Free, R Haider, J Drube, AK Ghosh, ... Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
GRK2 Enhances ß-arrestin Recruitment to the D2 Dopamine Receptor Through a Mechanism that is Independent From Receptor Phosphorylation or G Protein Activation N Boldizsar, M Sanchez-Soto, J Drube, R Haider, RB Free, C Hoffman, ... Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
beta-arrestin2 conformational changes are induced by mu-opioid receptor activation O Underwood, R Haider, JR Lane, S Briddon, C Hoffmann, M Canals BRITISH JOURNAL OF PHARMACOLOGY 180 (4), 484-485, 2023 | | 2023 |
GRK2/3/5/6 knockout cells: New tools to investigate impact of individual GRKs on arrestin binding and GPCR regulation J Drube, RS Haider, ESF Matthees, M Reichel, C Hoffmann NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 395 (SUPPL 1), S44-S44, 2022 | | 2022 |