Trichostatin A Is a Histone Deacetylase Inhibitor with Potent Antitumor Activity against Breast Cancer in Vivo DM Vigushin, S Ali, PE Pace, N Mirsaidi, K Ito, I Adcock, RC Coombes Clinical Cancer Research 7 (4), 971-976, 2001 | 586 | 2001 |
Human estrogen receptor β binds DNA in a manner similar to and dimerizes with estrogen receptor α P Pace, J Taylor, S Suntharalingam, RC Coombes, S Ali Journal of Biological Chemistry 272 (41), 25832-25838, 1997 | 446 | 1997 |
The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair W Niedzwiedz, G Mosedale, M Johnson, CY Ong, P Pace, KJ Patel Molecular cell 15 (4), 607-620, 2004 | 394 | 2004 |
Phosphorylation of human estrogen receptor α by protein kinase A regulates dimerization D Chen, PE Pace, RC Coombes, S Ali Molecular and cellular biology 19 (2), 1002-1015, 1999 | 379 | 1999 |
Activation of estrogen receptor α by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7 D Chen, T Riedl, E Washbrook, PE Pace, RC Coombes, JM Egly, S Ali Molecular cell 6 (1), 127-137, 2000 | 365 | 2000 |
Phosphorylation of human estrogen receptor α at serine 118 by two distinct signal transduction pathways revealed by phosphorylation-specific antisera D Chen, E Washbrook, N Sarwar, GJ Bates, PE Pace, ... Oncogene 21 (32), 4921-4931, 2002 | 307 | 2002 |
Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway P Pace, G Mosedale, MR Hodskinson, IV Rosado, M Sivasubramaniam, ... Science 329 (5988), 219-223, 2010 | 271 | 2010 |
Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI AF Alpi, PE Pace, MM Babu, KJ Patel Molecular cell 32 (6), 767-777, 2008 | 234 | 2008 |
The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway G Mosedale, W Niedzwiedz, A Alpi, F Perrina, JB Pereira-Leal, ... Nature structural & molecular biology 12 (9), 763-771, 2005 | 225 | 2005 |
Deubiquitination of FANCD2 is required for DNA crosslink repair VH Oestergaard, F Langevin, HJ Kuiken, P Pace, W Niedzwiedz, ... Molecular cell 28 (5), 798-809, 2007 | 213 | 2007 |
FANCE: the link between Fanconi anaemia complex assembly and activity P Pace, M Johnson, WM Tan, G Mosedale, C Sng, M Hoatlin, J De Winter, ... The EMBO journal, 2002 | 202 | 2002 |
Hyperoxidation of peroxiredoxins 2 and 3: rate constants for the reactions of the sulfenic acid of the peroxidatic cysteine AV Peskin, N Dickerhof, RA Poynton, LN Paton, PE Pace, MB Hampton, ... Journal of Biological Chemistry 288 (20), 14170-14177, 2013 | 185 | 2013 |
BRCA1-independent ubiquitination of FANCD2 CJ Vandenberg, F Gergely, CY Ong, P Pace, DL Mallery, K Hiom, ... Molecular cell 12 (1), 247-254, 2003 | 179 | 2003 |
An important role for BRCA1 in breast cancer progression is indicated by its loss in a large proportion of non‐familial breast cancers J Taylor, M Lymboura, PE Pace, RP A'hern, AJ Desai, S Shousha, ... International journal of cancer 79 (4), 334-342, 1998 | 147 | 1998 |
Model for the exceptional reactivity of peroxiredoxins 2 and 3 with hydrogen peroxide: a kinetic and computational study P Nagy, A Karton, A Betz, AV Peskin, P Pace, RJ O'Reilly, MB Hampton, ... Journal of Biological Chemistry 286 (20), 18048-18055, 2011 | 140 | 2011 |
Gliotoxin is a dual inhibitor of farnesyltransferase and geranylgeranyltransferase I with antitumor activity against breast cancer in vivo DM Vigushin, N Mirsaidi, G Brooke, C Sun, P Pace, L Inman, CJ Moody, ... Medical oncology 21, 21-30, 2004 | 129 | 2004 |
Glutathionylation of the active site cysteines of peroxiredoxin 2 and recycling by glutaredoxin AV Peskin, PE Pace, JB Behring, LN Paton, M Soethoudt, ... Journal of Biological Chemistry 291 (6), 3053-3062, 2016 | 117 | 2016 |
Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades M Dagnell, Q Cheng, SHM Rizvi, PE Pace, B Boivin, CC Winterbourn, ... Journal of Biological Chemistry 294 (33), 12330-12338, 2019 | 62 | 2019 |
Presence of exon 5-deleted oestrogen receptor in human breast cancer: functional analysis and clinical significance AJ Desai, YA Luqmani, JE Walters, RC Coope, B Dagg, JJ Gomm, ... British journal of cancer 75 (8), 1173-1184, 1997 | 57 | 1997 |
Hyperoxidized peroxiredoxin 2 interacts with the protein disulfide-isomerase ERp46 PE Pace, AV Peskin, MH Han, MB Hampton, CC Winterbourn Biochemical Journal 453 (3), 475-485, 2013 | 56 | 2013 |