The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR RM Chin, X Fu, MY Pai, L Vergnes, H Hwang, G Deng, S Diep, ... Nature 510 (7505), 397-401, 2014 | 639 | 2014 |
2-Hydroxyglutarate inhibits ATP synthase and mTOR signaling X Fu, RM Chin, L Vergnes, H Hwang, G Deng, Y Xing, MY Pai, S Li, L Ta, ... Cell metabolism 22 (3), 508-515, 2015 | 249 | 2015 |
Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses EJ Gillespie, CLC Ho, K Balaji, DL Clemens, G Deng, YE Wang, ... Proceedings of the National Academy of Sciences 110 (50), E4904-E4912, 2013 | 105 | 2013 |
Synthesis of α-diketones from alkylaryl-and diarylalkynes using mercuric salts ME Jung, G Deng Organic letters 16 (8), 2142-2145, 2014 | 62 | 2014 |
Antiestrogens in combination with immune checkpoint inhibitors in breast cancer immunotherapy DC Márquez-Garbán, G Deng, B Comin-Anduix, AJ Garcia, Y Xing, ... The Journal of steroid biochemistry and molecular biology 193, 105415, 2019 | 54 | 2019 |
Synthesis and biological evaluation of novel triptolide analogues for anticancer activity B Zhou, Z Miao, G Deng, J Ding, Y Yang, H Feng, Y Li Bioorganic & medicinal chemistry letters 20 (21), 6217-6221, 2010 | 32 | 2010 |
Synthesis and biological evaluation of C-2 halogenated analogs of salvinorin A DYW Lee, L Yang, W Xu, G Deng, L Guo, LY Liu-Chen Bioorganic & medicinal chemistry letters 20 (19), 5749-5752, 2010 | 23 | 2010 |
Partial amelioration of peripheral and central symptoms of Huntington’s disease via modulation of lipid metabolism JY Chen, C Tran, L Hwang, G Deng, ME Jung, KF Faull, MS Levine, ... Journal of Huntington's disease 5 (1), 65-81, 2016 | 19 | 2016 |
Synthesis of the 1-monoester of 2-ketoalkanedioic acids, for example, octyl α-ketoglutarate ME Jung, G Deng The Journal of organic chemistry 77 (23), 11002-11005, 2012 | 18 | 2012 |
Thermal degradation products derived from the smoke of Salvia divinorum leaves Z Ma, G Deng, R Dai, W Xu, LY Liu-Chen, DYW Lee Tetrahedron Letters 51 (41), 5480-5482, 2010 | 17 | 2010 |
A new route to stereoselective construction of 6β, 7β-methylene unit from androst-5-en-7-one G Deng, Z Li, SY Peng, L Fang, YC Li Tetrahedron 63 (22), 4630-4635, 2007 | 13 | 2007 |
Synthesis and biological evaluation of 2-alkyl-2-methoxymethyl-salvinorin ethers as selective κ-opioid receptor agonists DYW Lee, G Deng, Z Ma, W Xu, L Yang, J Liu, R Dai, LY Liu-Chen Bioorganic & medicinal chemistry letters 25 (20), 4689-4692, 2015 | 12 | 2015 |
Novel neoclerodane diterpene derivatives from the smoke of salvinorin A Z Ma, G Deng, DYW Lee Tetrahedron letters 51 (39), 5207-5209, 2010 | 11 | 2010 |
Stereospecific synthesis of drospirenone G Deng, Z Huang, X Zhao, Z Li, Y Li, B Jiang Chinese Journal of Chemistry 31 (1), 15-17, 2013 | 9 | 2013 |
Compositions and methods for treating aging and age-related diseases and symptoms J Huang, R Chin, S Diep, MY Pai, BE Lomenick, X Fu, K Reue, L Vergnes, ... US Patent App. 15/114,014, 2016 | 4 | 2016 |
Compounds and methods of treating cancer RJ Pietras, ME Jung, DC Marquez-Garban, G Deng US Patent 9,862,693, 2018 | 2 | 2018 |
Compositions and methods for treating cancer RJ Pietras, ME Jung, DC Marquez-Garban, G Deng US Patent 9,266,901, 2016 | 2 | 2016 |
Abstract PD03-04: Discovery of metformin derivatives with potent antitumor activity in triple-negative breast cancer DC Marquez-Garban, G Deng, N Anderson, L Aivazyan, N Kazmi, ... Cancer Research 72 (24_Supplement), PD03-04-PD03-04, 2012 | 2 | 2012 |
Novel metformin analogues for treatment of pancreatic cancer LP Burton, G Deng, CD Yanes, JV Vadgama, ME Jung, RJ Pietras, ... Journal of the Endocrine Society 5 (Supplement_1), A1027-A1028, 2021 | 1 | 2021 |
Estrogen receptor modulators RJ Pietras, ME Jung, DC Marquez-Garban, G Deng US Patent 10,400,006, 2019 | 1 | 2019 |